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Found 27 with Last Name = 'murthy' and Initial = 'kh'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037121(2-[(1R,3S,4S)-1-BENZYL-4-[N-(BENZYLOXYCARBONYL)-L-...)
Affinity DataKi:  0.600nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037124((R)-2-{(R)-2-[(S)-4-((S)-2-Benzyloxycarbonylamino-...)
Affinity DataKi:  0.700nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037122(CHEMBL108016 | [(1S,2S,4R)-1-Benzyl-2-hydroxy-4-(5...)
Affinity DataKi:  83nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037126(CHEMBL80098 | [(1S,2S,4R)-1-Benzyl-2-hydroxy-5-phe...)
Affinity DataKi:  92nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037125(CHEMBL107849 | {(S)-1-Benzyl-4-[(S)-1-(carbamoylme...)
Affinity DataKi:  120nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037128(CHEMBL419921 | [(1S,2S,4R)-1-Benzyl-4-(5-butyryl-1...)
Affinity DataKi:  150nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037123(CHEMBL108226 | {(1S,2S,4R)-1-Benzyl-4-[5-(2,2-dime...)
Affinity DataKi:  270nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037127(CHEMBL104285 | [(1S,2S,4R)-4-(5-Acetyl-1H-imidazol...)
Affinity DataKi:  370nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037120(CHEMBL104523 | {(1S,2S,4R)-1-Benzyl-2-hydroxy-4-[5...)
Affinity DataKi:  2.70E+3nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33265(guanidine, 5)
Affinity DataKi:  3.20E+3nM ΔG°:  -31.2kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037129(CHEMBL106776 | [(1S,2S,4R)-1-Benzyl-4-(5-formyl-1H...)
Affinity DataKi:  3.50E+3nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.6kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Alabama At Birmingham

LigandPNGBDBM33265(guanidine, 5)
Affinity DataKi:  1.30E+4nM ΔG°:  -27.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037119(CHEMBL448480 | {(1S,2S,4R)-1-Benzyl-2-hydroxy-4-[5...)
Affinity DataKi:  1.33E+4nMAssay Description:Apparent inhibition constant against recombinant HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University Of Alabama At Birmingham

LigandPNGBDBM33265(guanidine, 5)
Affinity DataKi:  1.40E+4nM ΔG°:  -27.5kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  1.60E+4nM ΔG°:  -27.2kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University Of Alabama At Birmingham

LigandPNGBDBM33264(guanidine, 4)
Affinity DataKi:  2.30E+4nM ΔG°:  -26.3kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Alabama At Birmingham

LigandPNGBDBM33261(biguanidine, 1)
Affinity DataKi:  3.50E+4nM ΔG°:  -25.3kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University Of Alabama At Birmingham

LigandPNGBDBM33261(biguanidine, 1)
Affinity DataKi:  4.40E+4nM ΔG°:  -24.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33262(biguanidine, 3)
Affinity DataKi:  5.10E+4nM ΔG°:  -24.3kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33261(biguanidine, 1)
Affinity DataKi:  8.70E+4nM ΔG°:  -23.0kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33260(biguanidine, 2)
Affinity DataKi:  1.55E+5nM ΔG°:  -21.6kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Alabama At Birmingham

LigandPNGBDBM33260(biguanidine, 2)
Affinity DataKi:  3.37E+5nM ΔG°:  -19.7kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University Of Alabama At Birmingham

LigandPNGBDBM33260(biguanidine, 2)
Affinity DataKi:  4.23E+5nM ΔG°:  -19.1kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1424-1463]/[1502-1685](West Nile virus (WNV))
University Of Alabama At Birmingham

LigandPNGBDBM33262(biguanidine, 3)
Affinity DataKi:  1.09E+6nM ΔG°:  -16.8kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen A(Bos taurus (bovine))
University Of Alabama At Birmingham

LigandPNGBDBM33260(biguanidine, 2)
Affinity DataKi:  1.35E+6nM ΔG°:  -16.3kJ/molepH: 7.6 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E](Dengue virus 2 (strain TSV01))
University Of Alabama At Birmingham

LigandPNGBDBM33262(biguanidine, 3)
Affinity DataKi:  1.78E+6nM ΔG°:  -15.6kJ/molepH: 8.5 T: 2°CAssay Description:All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed