Compile Data Set for Download or QSAR
maximum 50k data
Found 51 with Last Name = 'nicholls' and Initial = 'pj'
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataKi:  680nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025155(3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione ...)
Affinity DataKi:  800nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025151(3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione ...)
Affinity DataKi:  1.75E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025153(3-(4-Amino-phenyl)-1,3-dimethyl-pyrrolidine-2,5-di...)
Affinity DataKi:  1.75E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079818(1-[(2,3-Dihydro-benzofuran-2-yl)-(4-fluoro-phenyl)...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079814(1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079820(1-[(2,3-Dihydro-benzofuran-2-yl)-p-tolyl-methyl]-1...)
Affinity DataIC50:  590nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079816(1-[(2,4-Dichloro-phenyl)-(2,3-dihydro-benzofuran-2...)
Affinity DataIC50:  880nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079817(1-[(2,3-Dihydro-benzofuran-2-yl)-(4-fluoro-phenyl)...)
Affinity DataIC50:  2.17E+3nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85469(Diphenyl-p-benzoquinone, 6)
Affinity DataIC50:  2.70E+3nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079815(1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM24781(2-phenyl-1,4-benzoquinone, 10 | 2-phenylcyclohexa-...)
Affinity DataIC50:  5.70E+3nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  6.13E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50:  9.00E+3nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85468(17Beta-HSD Inhibitor, 3)
Affinity DataIC50:  9.15E+3nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50009001(5,6,7-Trihydroxyflavone | 5,6,7-trihydroxy-2-pheny...)
Affinity DataIC50:  9.30E+3nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025151(3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025155(3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione ...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85568(7-Hydroxy-flavone, 5c)
Affinity DataIC50:  1.01E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025154(3-(4-Amino-phenyl)-pyrrolidine-2,5-dione | CHEMBL1...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM9461(5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.08E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025155(3-(4-Amino-phenyl)-3-methyl-pyrrolidine-2,5-dione ...)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85567(7-Hydroxy-flavone, 5b)
Affinity DataIC50:  1.35E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025152(3-(4-Amino-phenyl)-3-ethyl-pyrrolidine-2,5-dione |...)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM34125(2-Phenylhydroquinone, 7 | hydroquinone derivative,...)
Affinity DataIC50:  1.48E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025153(3-(4-Amino-phenyl)-1,3-dimethyl-pyrrolidine-2,5-di...)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 uM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025153(3-(4-Amino-phenyl)-1,3-dimethyl-pyrrolidine-2,5-di...)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  1.64E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50081950(6-Hydroxy-2-phenyl-chromen-4-one | 6-Hydroxyflavon...)
Affinity DataIC50:  1.64E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025151(3-(4-Amino-phenyl)-1-methyl-pyrrolidine-2,5-dione ...)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against testosterone at 1.5 microM (Km=0.13 uM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)
Affinity DataIC50:  1.72E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50025154(3-(4-Amino-phenyl)-pyrrolidine-2,5-dione | CHEMBL1...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 against Androstenedione at 0.25 uM (Km=55 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85570(7-Hydroxy-flavone, 5e)
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011438(2-(4-Amino-phenyl)-7-hydroxy-chromen-4-one | 2-(4-...)
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  2.13E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  3.03E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM7457(2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  3.24E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50079819(1-[(2,4-Dichloro-phenyl)-(2,3-dihydro-benzofuran-2...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM71545(2-[4-[(Z)-2-chloranyl-1,2-diphenyl-ethenyl]phenoxy...)
Affinity DataIC50:  7.62E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85467(Tamoxifen, 1)
Affinity DataIC50:  9.81E+4nMpH: 7.45 T: 2°CAssay Description:Inhibition assay of human testes mcrosomal 17 beta-hydroxysteroid dehydrogenase for the reduction of androstenedione.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85571(7-Hydroxy-flavone, 5f)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85575(7-Hydroxy-flavone, 8)
Affinity DataIC50:  1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85574(7-Hydroxy-flavone, 7)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85572(7-Hydroxy-flavone, 5g)
Affinity DataIC50: >1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85573(7-Hydroxy-flavone, 5h)
Affinity DataIC50:  1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM85569(7-Hydroxy-flavone, 5d)
Affinity DataIC50:  1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 51 total ) | Next | Last >>
Jump to: