BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254931(US9499542, 14 | US9675594, 14)

Ki: 0.100nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214466(CHEMBL398149 | N-(3-(8-cyano-4-(cyclopropylamino)p...)

Ki: 0.260nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214473(CHEMBL230354 | N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZO...)

Ki: 0.350nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254929(US9499542, 12 | US9675594, 12)

Ki: 0.5nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374656(CHEMBL401544)

Ki: 0.800nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374653(CHEMBL271020)

Ki: 1.30nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374654(CHEMBL271645)

Ki: 1.40nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374662(CHEMBL256401)

Ki: 1.40nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM50364234(CHEMBL1952279)

Ki: 1.5nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136934(3',4'-Dichloro-biphenyl-3-sulfonic acid (3-chloro-...)

Ki: 1.60nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Sodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL

BDBM50191330(4,5,6,7,8,9,10,11,13,17a,18,19,20,21,22,22a-hexade...)

Ki: 1.90nMAssay Description:Displacement of [3H]paroxetine from human 5HTTMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214454(CHEMBL230462 | N-(3-(8-cyano-4-(cyclobutylamino)py...)

Ki: 1.90nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374658(CHEMBL401614)

Ki: 2nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254929(US9499542, 12 | US9675594, 12)

Ki: 2nMAssay Description:Inhibition of human wild type LRRK2 phosphorylation at ser935 transfected in HEK293 cells after 48 hrs by in-cell Western assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374651(CHEMBL257219)

Ki: 2.20nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374655(CHEMBL401945)

Ki: 2.40nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50118185((3S,8R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[...)

Ki: 2.58nMAssay Description:Tested for the binding affinity towards Serotonin transporter in rat midbrain tissue by displacing [3H]paroxetine radioligandMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254928(US9499542, 11 | US9675594, 11)

Ki: 3nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374657(CHEMBL257736)

Ki: 3.40nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136916(3'-Chloro-4'-fluoro-biphenyl-3-sulfonic acid (3-ch...)

Ki: 3.40nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374660(CHEMBL256189)

Ki: 3.60nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136914(4'-Chloro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)

Ki: 3.90nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254919(US9499542, 2 | US9675594, 2)

Ki: 4nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374659(CHEMBL402246)

Ki: 4nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214444(2-(p-toluidino)-4-(phenylamino)pyrazolo[1,5-a][1,3...)

Ki: 5nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214465(2-(4-chlorobenzylamino)-4-(phenylamino)pyrazolo[1,...)

Ki: 5nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374661(CHEMBL402306)

Ki: 5.20nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254918(US9499542, 1 | US9675594, 1)

Ki: 6nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254918(US9499542, 1 | US9675594, 1)

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar

Cannabinoid receptor 1(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM50296485((R)-{3-[(4-Chlorophenyl)-(2-chloropyridin-3-yl)met...)

Ki: 7nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214477(4-(phenylamino)-2-(4-(pyridin-2-yl)piperazin-1-yl)...)

Ki: 7nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Casein kinase II subunit alpha(Zea mays (Maize))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50374652(CHEMBL271848)

Ki: 7.40nMAssay Description:Inhibition of corn CK2More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214474(CHEMBL230353 | N-(3-(8-cyano-4-(phenethylamino)pyr...)

Ki: 8nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214460(2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[...)

Ki: 8nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

CHEMBL DrugBank MMDB PC cid PC sid PDB Similars

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136919(3',4'-Difluoro-biphenyl-3-sulfonic acid (3-chloro-...)

Ki: 8.10nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214448(2-(3,4-dimethoxyphenylamino)-4-(phenylamino)pyrazo...)

Ki: 9nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136913(CHEMBL156794 | N-(3-Chloro-7-isobutylamino-1H-inda...)

Ki: 10.8nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214464(CHEMBL230568 | N-(3-(8-methyl-4-(phenylamino)pyraz...)

Ki: 11nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214450(2-(3,4-dihydroisoquinolin-2(1H)-yl)-4-(phenylamino...)

Ki: 11nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136936(3'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)

Ki: 11nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254928(US9499542, 11 | US9675594, 11)

Ki: 12nMAssay Description:Inhibition of recombinant human GST-tagged LRRK2 G2019S mutant (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrat...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214457(2-(2,3-dihydro-1H-inden-2-ylamino)-4-(phenylamino)...)

Ki: 12nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136942(4'-Chloro-biphenyl-3-sulfonic acid (3-chloro-7-iso...)

Ki: 12.5nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM50250336(CHEMBL4068861)

Ki: 13nMAssay Description:Inhibition of wild type recombinant human GST-tagged LRRK2 (970 to 2527 residues) expressed in baculovirus using fluorescein-LRRKtide as substrate af...More data for this Ligand-Target Pair

PC cid PC sid PDB Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Vernalis (R&D)

Curated by ChEMBL

BDBM254919(US9499542, 2 | US9675594, 2)

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136911(4'-Trifluoromethyl-biphenyl-3-sulfonic acid (3-chl...)

Ki: 13nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214453(2-(isopentylamino)-4-(phenylamino)pyrazolo[1,5-a][...)

Ki: 13nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Casein kinase II subunit alpha(Homo sapiens (Human))
Polaris Pharmaceuticals

Curated by ChEMBL

BDBM50214468(4-(phenylamino)-2-(pyrrolidin-1-yl)pyrazolo[1,5-a]...)

Ki: 14nMAssay Description:Inhibition of human CK2 alphaMore data for this Ligand-Target Pair

PDB MMDB KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Quorex Pharmaceuticals

Curated by ChEMBL

BDBM50136918(4'-Fluoro-3'-methyl-biphenyl-3-sulfonic acid (3-ch...)

Ki: 14.6nMAssay Description:Inhibition of Escherichia coli S-adenosyl homocysteine/methylthioadenosine nucleosidase (MTA/SAH nucleosidase)More data for this Ligand-Target Pair