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Found 270 with Last Name = 'niimi' and Initial = 't'
TargetAndrogen receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  4.60nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  6.20nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
Astellas Pharma

LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataKi:  14nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Astellas Pharma

LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataKi:  19nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
TargetProgesterone receptor(Rattus norvegicus)
Astellas Pharma

LigandPNGBDBM18656((2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-...)
Affinity DataKi:  3.30E+3nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Rattus norvegicus)
Astellas Pharma

LigandPNGBDBM18525(Bicalutamide | CHEMBL409 | N-[4-cyano-3-(trifluoro...)
Affinity DataKi:  7.20E+3nMAssay Description:The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd] where [L] is the concentration of labeled ligand a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196658(US10202399, Example 15 | US9212147, 15)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196658(US10202399, Example 15 | US9212147, 15)
Affinity DataIC50:  1.20nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431067(CHEMBL2338797 | US10202399, Example 18 | US1046366...)
Affinity DataIC50:  1.40nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50260725(4H-thieno[3,2-b]pyrrole-5-carboxylic acid | CHEMBL...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431067(CHEMBL2338797 | US10202399, Example 18 | US1046366...)
Affinity DataIC50:  1.40nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431067(CHEMBL2338797 | US10202399, Example 18 | US1046366...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431083(CHEMBL2338803 | US10202399, Example 24 | US1046366...)
Affinity DataIC50:  1.5nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431083(CHEMBL2338803 | US10202399, Example 24 | US1046366...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431083(CHEMBL2338803 | US10202399, Example 24 | US1046366...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431067(CHEMBL2338797 | US10202399, Example 18 | US1046366...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431074(CHEMBL2338790 | US10463663, Example 27 | US1112982...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431069(CHEMBL2338795 | US10202399, Example 27 | US1046366...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431069(CHEMBL2338795 | US10202399, Example 27 | US1046366...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431069(CHEMBL2338795 | US10202399, Example 27 | US1046366...)
Affinity DataIC50:  2nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196659(US9212147, 16)
Affinity DataIC50:  2.10nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431065(CHEMBL2338799 | US10202399, Example 16)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431065(CHEMBL2338799 | US10202399, Example 16)
Affinity DataIC50:  2.10nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196661(US10202399, Example 21 | US10463663, Example 17 | ...)
Affinity DataIC50:  2.20nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431070(CHEMBL2338794)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431066(CHEMBL2338798 | US10202399, Example 17 | US1046366...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431086(CHEMBL2338800 | US10202399, Example 212 | US104636...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196675(US10202399, Example 237 | US9212147, 237)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196675(US10202399, Example 237 | US9212147, 237)
Affinity DataIC50:  2.20nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196671(US10202399, Example 56 | US9212147, 56)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196674(US10202399, Example 232 | US9212147, 232)
Affinity DataIC50:  2.30nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431066(CHEMBL2338798 | US10202399, Example 17 | US1046366...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196671(US10202399, Example 56 | US9212147, 56)
Affinity DataIC50:  2.30nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196674(US10202399, Example 232 | US9212147, 232)
Affinity DataIC50:  2.30nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431066(CHEMBL2338798 | US10202399, Example 17 | US1046366...)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431078(CHEMBL2338786 | US10463663, Example 1 | US11129828...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431066(CHEMBL2338798 | US10202399, Example 17 | US1046366...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196654(US9212147, 1)
Affinity DataIC50:  2.40nMpH: 7.5 T: 2°CAssay Description:This test was performed by partially modifying the method of Philip et. al. (J. Biomol. Screen. Vol. 11, pp 481-487, 2006). HEK293 cells that stably ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431066(CHEMBL2338798 | US10202399, Example 17 | US1046366...)
Affinity DataIC50:  2.40nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431074(CHEMBL2338790 | US10463663, Example 27 | US1112982...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Mus musculus)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431086(CHEMBL2338800 | US10202399, Example 212 | US104636...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of mouse full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196660(US10202399, Example 20 | US9212147, 20)
Affinity DataIC50:  2.5nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196660(US10202399, Example 20 | US9212147, 20)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196670(US10202399, Example 52 | US9212147, 52)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM196670(US10202399, Example 52 | US9212147, 52)
Affinity DataIC50:  2.5nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Rattus norvegicus (rat))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50431067(CHEMBL2338797 | US10202399, Example 18 | US1046366...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of rat full length DAAO overexpressed in HEK293 cells after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM347109(US10202399, Example 254)
Affinity DataIC50:  2.70nMAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431074(CHEMBL2338790 | US10463663, Example 27 | US1112982...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of human recombinant DAAO after 30 mins by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM50431074(CHEMBL2338790 | US10463663, Example 27 | US1112982...)
Affinity DataIC50:  2.70nMpH: 7.5 T: 2°CAssay Description:The DAAO inhibitory activity was measured by assaying the amount of hydrogen peroxide (H2O2) produced by reacting DAAO protein with flavin adenine di...More data for this Ligand-Target Pair
In DepthDetails US Patent
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