Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 138nMAssay Description:Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 159nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 6.65E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: >1.25E+4nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.22E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.89E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.14E+3nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 174nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.81E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.42E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 440nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 273nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 214nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 684nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 474nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 216nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.43E+3nMAssay Description:Activity against human GLUR2 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 489nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 333nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 97nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+3nMAssay Description:Activity against human GLUR4 flop expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 559nMAssay Description:Activity against human GLUR2 flip expressed in HEK293 cells assesed as glutamate-stimulated calcium influx by FLIPR assayMore data for this Ligand-Target Pair