Compile Data Set for Download or QSAR
maximum 50k data
Found 82 with Last Name = 'norbeck' and Initial = 'dw'
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099843((S)-N-[(S)-4-[2-(2,6-Dimethyl-phenoxy)-acetylamino...)
Affinity DataKi:  0.00100nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM578((2S)-N-[(2S,4S,5S)-5-[2-(2,6-dimethylphenoxy)aceta...)
Affinity DataKi:  0.00100nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099842((S)-N-[(S)-4-[2-(2,6-Dimethyl-phenoxy)-acetylamino...)
Affinity DataKi:  0.00100nMAssay Description:Inhibitory activity against HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM200((2S)-N-[(2S,3R,5S)-3-hydroxy-5-[(2S)-3-methyl-2-{[...)
Affinity DataKi:  0.00400nM ΔG°:  -66.1kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM194((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxy-...)
Affinity DataKi:  0.00500nM ΔG°:  -65.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM198((2S)-N-[(2S,3S,4S,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.0110nM ΔG°:  -63.6kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM199((2S)-N-[(2S,3R,4S,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.0120nM ΔG°:  -63.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM520(1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...)
Affinity DataKi:  0.0150nMAssay Description:Inhibition constant of ritonavir towards HIV protease was determinedMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM520(1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[...)
Affinity DataKi:  0.0200nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM195((5R,6R)-1,5-dibenzyl-2-(cyclopropylmethyl)-6-hydro...)
Affinity DataKi:  0.0620nM ΔG°:  -59.2kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM192((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(4-hydroxyp...)
Affinity DataKi:  0.0700nM ΔG°:  -58.9kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM197((2S)-N-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi:  0.112nM ΔG°:  -57.7kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM189((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis({[4-(hydrox...)
Affinity DataKi:  0.220nM ΔG°:  -56.0kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM193((5R,6R)-1,5-dibenzyl-6-hydroxy-2,4-bis[(3-methoxyp...)
Affinity DataKi:  0.220nM ΔG°:  -56.0kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM190((5R,6R)-2,4-Bis[4-(hydroxymethyl)benzyl]-1-(3-fura...)
Affinity DataKi:  0.490nM ΔG°:  -54.0kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM191((5R,6R)-1,2,4,5-tetrabenzyl-6-hydroxy-1,2,4-triaze...)
Affinity DataKi:  2nM ΔG°:  -50.5kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Nci-Fcrdc

LigandPNGBDBM196(A-74704 | CHEMBL307193 | benzyl N-[(1S)-1-{[(2S,4S...)
Affinity DataKi:  4.5nM ΔG°:  -48.4kJ/molepH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay using the internally quenched fluorogenic substrate DABCYL-GABA-Ser-Gln-Tyr-P...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014145(CHEMBL314298 | {1-[1-Benzyl-4-(2-benzyloxycarbonyl...)
Affinity DataIC50:  0.220nMAssay Description:Inhibitory activity against recombinant HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014144(CHEMBL83462 | {(S)-1-[(1S,2R,3R,4S)-1-Benzyl-4-((R...)
Affinity DataIC50:  0.220nMAssay Description:Inhibitory activity against recombinant HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014149(CHEMBL314758 | {1-[1-Benzyl-4-(2-benzyloxycarbonyl...)
Affinity DataIC50:  0.380nMAssay Description:Inhibitory activity against recombinant HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50063071(((1S,2S,4S)-1-Benzyl-2-hydroxy-4-{3-[3-(2-isopropy...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174973((5R,6R)-2,4-bis(4-hydroxy-3-methoxybenzyl)-5-benzy...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062997(((1S,2S,4S)-1-Benzyl-2-hydroxy-4-{2-[3-(2-isopropy...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062946(((1S,3S,4S)-1-Benzyl-3-hydroxy-4-{3-[3-(2-isopropy...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285916(CHEMBL90751 | [(1S,2S,4S)-1-Benzyl-4-(2-chloro-4-h...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285903(CHEMBL93589 | [(1S,3S,4S)-1-Benzyl-4-(2-chloro-4-h...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062994(((1S,3S,4S)-1-Benzyl-3-hydroxy-4-{2-[3-(2-isopropy...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285910(CHEMBL93718 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(3-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062954(((1S,2S,4S)-1-Benzyl-2-hydroxy-4-{2-[3-isobutyl-3-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062941(((1S,3S,4S)-1-Benzyl-4-{2-[3-cyclopropyl-3-(2-isop...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062969(CHEMBL346943 | {(1S,3S,4S)-1-Benzyl-3-hydroxy-4-[2...)
Affinity DataIC50:  1.90nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174993((5R,6R)-2,4-bis(4-hydroxy-3-methoxybenzyl)-5-benzy...)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory activity against HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062939(CHEMBL347824 | [(1S,2S,4S)-1-Benzyl-4-(2-{3-ethyl-...)
Affinity DataIC50:  2.30nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285911(CHEMBL90090 | [(1S,3S,4S)-4-(3-Amino-2-methyl-benz...)
Affinity DataIC50:  2.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014147(A-74704 | CHEMBL430891 | {(S)-1-[(1S,3S)-1-Benzyl-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285890(CHEMBL93566 | [(1S,3S,4S)-4-(5-Amino-2-chloro-benz...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285913(CHEMBL327611 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(4...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285905(CHEMBL93540 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(4-...)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285897(CHEMBL273562 | [(1S,3S,4S)-1-Benzyl-3-hydroxy-4-(3...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285900(CHEMBL93481 | [(1S,3S,4S)-4-(4-Amino-2-chloro-benz...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174986((5R,6R)-2,4-bis(4-hydroxy-3-methoxybenzyl)-5-benzy...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory activity against HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062925(CHEMBL157673 | [(1S,2S,4S)-1-Benzyl-2-hydroxy-4-(2...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory concentration against purified recombinant HIV-1 protease using fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285906(CHEMBL328531 | [(1S,3S,4S)-1-Benzyl-4-(3,4-dihydro...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285899(((1S,3S,4S)-4-Benzoylamino-1-benzyl-3-hydroxy-5-ph...)
Affinity DataIC50:  4.5nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014146(CHEMBL90174 | {1-[1-Benzyl-3-(2-benzyloxycarbonyla...)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against recombinant HIV-1 ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285889(((1S,3S,4S)-1-Benzyl-4-tert-butoxycarbonylamino-3-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285907(CHEMBL93323 | [(1S,3S,4S)-4-(3-Amino-2-chloro-benz...)
Affinity DataIC50:  5.30nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285892(((1S,3S,4S)-1-Benzyl-4-benzyloxycarbonylamino-3-hy...)
Affinity DataIC50:  5.60nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50174969((5R,6R)-2,4-bis(4-hydroxy-3-methoxybenzyl)-5-benzy...)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory activity against HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285915(CHEMBL91657 | [(1S,2S,4S)-4-(4-Amino-2-chloro-benz...)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory activity against purified HIV proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
Displayed 1 to 50 (of 82 total ) | Next | Last >>
Jump to: