Compile Data Set for Download or QSAR
maximum 50k data
Found 191 with Last Name = 'pagliuca' and Initial = 'c'
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM29080(CHEMBL280065 | N-oleoylethanolamine | Oleamide MEA...)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of acid ceramidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367209(2-oxo-4-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  0.800nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367226(4-fluoro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  1nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367194(5-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  3nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367195(6-nitro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  3nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431244(CHEMBL2333064)
Affinity DataIC50:  4nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431246(CHEMBL2333062 | US9428465, 32)
Affinity DataIC50:  7nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431255(CHEMBL2333053)
Affinity DataIC50:  7nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151154(CHEMBL3770896)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431246(CHEMBL2333062 | US9428465, 32)
Affinity DataIC50:  7nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367187(5-chloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  9nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367186(6-fluoro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  10nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50:  10nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367198(5-cyano-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  11nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367196(2-oxo-N-(4-phenylbutyl)-5- (trifluoromethyl)-1,3- ...)
Affinity DataIC50:  11nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431254(CHEMBL2333054)
Affinity DataIC50:  12nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151242(CHEMBL3770525)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431260(CHEMBL2333048)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM241946(US9428465, 24)
Affinity DataIC50:  14nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367214(6-(4-chlorobenzoyl)-2-oxo-N- (4-phenylbutyl)-1,3- ...)
Affinity DataIC50:  14nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50577403(CHEMBL4878464)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431253(CHEMBL2333055)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367212(2-oxo-N-(4-phenylbutyl)-6- propanoyl-1,3-benzoxazo...)
Affinity DataIC50:  16nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50577404(CHEMBL4864438)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367199(5,6-dichloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxa...)
Affinity DataIC50:  18nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431258(CHEMBL2333050)
Affinity DataIC50:  18nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367201(7-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  18nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367217(2-oxo-N-[(4- propylphenyl)methyl]-1,3- benzoxazole...)
Affinity DataIC50:  19nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50577396(CHEMBL4863119)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431252(CHEMBL2333056)
Affinity DataIC50:  20nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367197(2-oxo-N-(4-phenylbutyl)-6- (trifluoromethyl)-1,3- ...)
Affinity DataIC50:  20nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431256(CHEMBL2333052)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367189(5-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  22nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151055(CHEMBL3771111)
Affinity DataIC50:  22nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367202(2-oxo-5-phenyl-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  22nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50577394(CHEMBL4848541)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367200(7-methyl-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  23nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151154(CHEMBL3770896)
Affinity DataIC50:  23nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells after 30 mins by UPLC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367223(2-oxo-N-[4-(p-tolyl)butyl]- 1,3-benzoxazole-3- car...)
Affinity DataIC50:  28nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431275(CARMOFUR | Carm-ofur | Mifurol | med.21724, Compou...)
Affinity DataIC50:  29nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367213(6-benzoyl-2-oxo-N-(4-phenyl- butyl)-1,3-benzoxazol...)
Affinity DataIC50:  29nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151155(CHEMBL3769844)
Affinity DataIC50:  33nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367188(6-chloro-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole...)
Affinity DataIC50:  33nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367190(6-bromo-2-oxo-N-(4- phenylbutyl)-1,3- benzoxazole-...)
Affinity DataIC50:  33nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM367218(N-octyl-2-oxo-1,3- benzoxazole-3-carboxamide | US1...)
Affinity DataIC50:  34nMAssay Description:The assay was performed in Optiplate 96-wells black plates, with each reaction well containing a mixture of 25 mM sodium acetate buffer pH 4.5 and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAcid ceramidase(Homo sapiens (Human))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50431262(CHEMBL2333042 | US9428465, 5)
Affinity DataIC50:  35nMpH: 4.5Assay Description:A hAC protein preparation (10 μg) was preincubated with inhibitors (final DMSO concentration 1%) in assay buffer (100 mM sodium phosphate, 0.1% ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50577388(CHEMBL4871884)
Affinity DataIC50:  36nMAssay Description:Inhibition of recombinant human NAAA expressed in HEK293 cells using PAMCA as fluorogenic substrate preincubated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Italian Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50151240(CHEMBL3770558)
Affinity DataIC50:  37nMAssay Description:Inhibition of human NAAA expressed in HEK293 cells preincubated for 10 mins followed by N-(4-methyl-2-oxo-chromen-7-yl)-hexadecanamide substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 191 total ) | Next | Last >>
Jump to: