Affinity DataKi: 250nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
Affinity DataKi: 360nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetSqualene synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
University Of Illinois At Urbana-Champaign
Curated by ChEMBL
Affinity DataKi: 740nMAssay Description:Inhibition of human squalene synthaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human cyclophilin A at 6 degCMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute
Curated by ChEMBL
Prenylx Research Institute
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair