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Found 149 with Last Name = 'pang' and Initial = 'r'
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50388903(CHEMBL2063253)
Affinity DataKi:  250nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50388398(CHEMBL561057 | SQ-109)
Affinity DataKi:  360nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50388906(CHEMBL2063256)
Affinity DataKi:  450nMAssay Description:Inhibition of Staphylococcus aureus His6-tagged CrtM expressed in Escherichia coli BL21(DE3) using Farnesyl pyrophosphate as substrate incubated for ...More data for this Ligand-Target Pair
TargetSqualene synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50388398(CHEMBL561057 | SQ-109)
Affinity DataKi:  740nMAssay Description:Inhibition of human squalene synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene synthase(Staphylococcus aureus)
TBA

Curated by ChEMBL
LigandPNGBDBM50388397(CHEMBL39581)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Staphylococcus aureus ATCC 27659 dehydrosqualene synthase expressed in Escherichia coli BL21(DE3) after 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University

Curated by ChEMBL
LigandPNGBDBM2198((3-(2-tert-Butyl-5-methyl-phenylsulfanyl)-4-hydrox...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50158830(CHEMBL3785583)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM195608(CPI-455)
Affinity DataIC50:  10nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University

Curated by ChEMBL
LigandPNGBDBM50168218(4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-m-tolyl...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50153092(CHEMBL3775894)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50540061(CHEMBL4637168)
Affinity DataIC50:  20nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428292(CHEMBL2338356)
Affinity DataIC50:  30nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428292(CHEMBL2338356)
Affinity DataIC50:  30nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428291(CHEMBL2338355)
Affinity DataIC50:  34nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Peking University

Curated by ChEMBL
LigandPNGBDBM50054619(4-Hydroxy-6-phenethyl-3-(1-phenyl-propyl)-6-propyl...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration against human immunodeficiency virus 1 protease in MT-4 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428296(CHEMBL2338360)
Affinity DataIC50:  36nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428295(CHEMBL2338359)
Affinity DataIC50:  40nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428312(CHEMBL2338376)
Affinity DataIC50:  40nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428313(CHEMBL2338377)
Affinity DataIC50:  43nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428311(CHEMBL2338375)
Affinity DataIC50:  44nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428294(CHEMBL2338358)
Affinity DataIC50:  44nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428290(CHEMBL2338354)
Affinity DataIC50:  49nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428293(CHEMBL2338357)
Affinity DataIC50:  49nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428310(CHEMBL2338374)
Affinity DataIC50:  58nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428307(CHEMBL2338371)
Affinity DataIC50:  66nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428308(CHEMBL2338372)
Affinity DataIC50:  79nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428306(CHEMBL2338370)
Affinity DataIC50:  80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428289(CHEMBL2338353)
Affinity DataIC50:  80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428297(CHEMBL2338361)
Affinity DataIC50:  80nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  100nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428313(CHEMBL2338377)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428296(CHEMBL2338360)
Affinity DataIC50:  100nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428314(CHEMBL2338378)
Affinity DataIC50:  100nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428309(CHEMBL2338373)
Affinity DataIC50:  110nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428314(CHEMBL2338378)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428295(CHEMBL2338359)
Affinity DataIC50:  110nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428297(CHEMBL2338361)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428293(CHEMBL2338357)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428290(CHEMBL2338354)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428294(CHEMBL2338358)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428298(CHEMBL2338362)
Affinity DataIC50:  120nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50267744(4-(3-(4-Chlorophenyl)thioureido)-N-(thiazol-2-yl)b...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human cyclophilin A at 6 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataIC50:  130nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428308(CHEMBL2338372)
Affinity DataIC50:  130nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428304(CHEMBL2338368)
Affinity DataIC50:  140nMAssay Description:Inhibition of His6-tagged human truncated FPPS (6-353) expressed in Escherichia coli BL21(DE3) cells using geranyl diphosphate and isopentenyl diphos...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428315(CHEMBL2338379)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428307(CHEMBL2338371)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428289(CHEMBL2338353)
Affinity DataIC50:  150nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Prenylx Research Institute

Curated by ChEMBL
LigandPNGBDBM50428312(CHEMBL2338376)
Affinity DataIC50:  160nMAssay Description:Binding affinity to human FPPS at 1 mM by X-ray crystallographic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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