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Found 290 with Last Name = 'parang' and Initial = 'k'
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370722(CHEMBL1791358)
Affinity DataKi:  210nMAssay Description:Inhibition of SRC in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50200200((S)-2-amino-N-hydroxy-3-(4-hydroxyphenyl)propanami...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50187738(Ac-Cys-Ile-cyclo[Phe-Lys]-Tyr-Tyr | CHEMBL428631)
Affinity DataIC50:  280nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of c-Src after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-tagged c-Src preincubated for 30 mins measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  500nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  500nMAssay Description:Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370722(CHEMBL1791358)
Affinity DataIC50:  530nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Affinity DataIC50:  600nMAssay Description:Inhibition of His6-tagged c-Src kinase domain using AEEEIYGEFEAKKKK as substrate pre-incubated for 10 mins before substrate addition measured after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  600nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370720(CHEMBL1791362)
Affinity DataIC50:  780nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50433806(CHEMBL2382016)
Affinity DataIC50:  800nMAssay Description:Inhibition of GST-fused Csk (unknown origin) expressed in Escherichia coli using polyE4Y as substrate after 20 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370725(CHEMBL1791373)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370343(CHEMBL1790802)
Affinity DataIC50:  1.10E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370348(CHEMBL1790811)
Affinity DataIC50:  1.20E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370729(CHEMBL1791361)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370341(CHEMBL1790810)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370735(CHEMBL1791374)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50187732(Ac-Cys-Ile-cyclo[Phe-Lys]-Tyr-Tyr | CHEMBL209045)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370724(CHEMBL1791376)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200197((S)-2-amino-N-hydroxy-3-(4-hydroxyphenyl)propaneth...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of GST-tagged c-Src preincubated for 30 mins measured after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50142887(1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo[...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of c-Src after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50433806(CHEMBL2382016)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of GST-fused Abl (unknown origin) expressed in Escherichia coli using CrkL as substrate after 20 mins by scintillation counting analysis i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200187((S)-2-amino-N-hydroxy-3-(4-iodophenyl)propanamide ...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200208((S)-2-amino-N-hydroxy-3-(4-isopropylphenyl)propana...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370351(CHEMBL1790806)
Affinity DataIC50:  3.30E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200198((S)-2-amino-N-hydroxy-3-(4-hydroxy-3,5-diiodopheny...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370730(CHEMBL1791372)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200190((S)-2-amino-N-hydroxy-3-(2-iodophenyl)propanamide ...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200189((S)-2-amino-N-hydroxy-3-[4-(nitrophenyl)phenyl]pro...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370728(CHEMBL1791375)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200196((S)-2-amino-3-(4-bromophenyl)-N-hydroxypropionamid...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50337691(1-(2-(4-Hexyl-1H-1,2,3-triazol-1-yl)ethyl)-3-pheny...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370352(CHEMBL1790807)
Affinity DataIC50:  5.90E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370731(CHEMBL1791368)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200201((S)-2-amino-N-hydroxy-3-[3-(nitrophenyl)phenyl]pro...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50337693(1-(2-Azidoethyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimi...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200188((S)-2-amino-3-(4-chlorophenyl)-N-hydroxypropanamid...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50187729(CHEMBL429525 | Cyclo[Ac-Cys-Ile-Tyr-Lys-Tyr-Tyr])
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50101077((1S,4S)-2-((S)-2-{(S)-2-[2-Amino-3-(4-phosphonooxy...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibitory concentration against Src protein tryrosine kinase SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50074242((2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Acetylamino-3-(4-ph...)
Affinity DataIC50:  6.50E+3nMAssay Description:Concentration of compoound required for inhibiting the binding of the fluorescent probe to the c-Src tyrosine kinase SH2 domain by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200206((S)-2-amino-N-hydroxy-3-(4-nitrophenyl)propanamide...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370737(CHEMBL1791356)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50337678(3-(4-((4-Amino-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of GST-fussed c-SRC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200200((S)-2-amino-N-hydroxy-3-(4-hydroxyphenyl)propanami...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM50200203((S)-2-amino-N-hydroxy-3-p-tolylpropionamide | CHEM...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of CSK measured as poly-E4Y phosphorylation by acid precipitation assay in presence of 0.2 mM CoCl2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Rhode Island

Curated by ChEMBL
LigandPNGBDBM50370718(CHEMBL1791371)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of SRC using polyE4Y as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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