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Found 117 with Last Name = 'park' and Initial = 'sb'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM167444(US9073906, 156)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537919(CHEMBL4633146)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537918(CHEMBL3951168)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537922(CHEMBL4645319)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537919(CHEMBL4633146)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537918(CHEMBL3951168)
Affinity DataIC50:  1nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537922(CHEMBL4645319)
Affinity DataIC50:  1nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537921(CHEMBL4649416)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM167444(US9073906, 156)
Affinity DataIC50:  2nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537917(CHEMBL4648389)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50:  4nMAssay Description:Inhibition of HER4 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537917(CHEMBL4648389)
Affinity DataIC50:  14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537920(CHEMBL4632806)
Affinity DataIC50:  17nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)
Affinity DataIC50:  22.4nMAssay Description:Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  36nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  36.3nMAssay Description:Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537916(CHEMBL4646414)
Affinity DataIC50:  49nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  52nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)
Affinity DataIC50:  52.2nMAssay Description:Inhibition of wild-type EGFR preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537916(CHEMBL4646414)
Affinity DataIC50:  68nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chungnam University

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataIC50:  97nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Abl1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Her4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50: <100nMAssay Description:Inhibition of Her4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chungnam University

Curated by ChEMBL
LigandPNGBDBM50511072(METHYL 7-DESHYDROXYPYROGALLIN-4-CARBOXYLATE)
Affinity DataIC50:  161nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537915(CHEMBL4638272)
Affinity DataIC50:  174nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537915(CHEMBL4638272)
Affinity DataIC50:  231nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Affinity DataIC50:  243nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chungnam University

Curated by ChEMBL
LigandPNGBDBM50511066(CHEMBL4467577)
Affinity DataIC50:  277nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Abl1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537923(CHEMBL4638268)
Affinity DataIC50:  529nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300027((S)-1-Acryloyl-N-[4-(3-chloro-2,4-difluorophenylam...)
Affinity DataIC50:  600nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537923(CHEMBL4638268)
Affinity DataIC50:  695nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  700nMAssay Description:Inhibition of RetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM50300026((S)-1-Acryloyl-N-[4-(3-chloro-2-fluorophenylamino)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537921(CHEMBL4649416)
Affinity DataIC50:  940nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chungnam University

Curated by ChEMBL
LigandPNGBDBM50511068(CHEMBL4459515)
Affinity DataIC50:  949nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Korea Research Institute Of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50537924(CHEMBL4647977)
Affinity DataIC50:  981nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHOK1 cells using XL665-labeled cortisol as substrate measured after 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Chungnam University

Curated by ChEMBL
LigandPNGBDBM50511075(CHEMBL4447485)
Affinity DataIC50:  985nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using 2P-IRS1 peptide as substrate after 1 hr by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Her1 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hanmi Research Center

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Her2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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