Compile Data Set for Download or QSAR
maximum 50k data
Found 87 with Last Name = 'parratt' and Initial = 'mj'
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17149(2-imino-thiazolidin-4-one analog, 11 | 4-(5-{[(5Z)...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11439(4-({5-[(4-aminocyclohexyl)amino]-3-bromopyrazolo[1...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11429(4-({5-[(4-aminocyclohexyl)amino]-3-cyclopentylpyra...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11430(4-({5-[(4-aminocyclohexyl)amino]-3-cyanopyrazolo[1...)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11431(4-({5-[(4-aminocyclohexyl)amino]-3-chloropyrazolo[...)
Affinity DataIC50:  8nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11432(4-({5-[(4-aminocyclohexyl)amino]-3-bromopyrazolo[1...)
Affinity DataIC50:  10nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11440(5-N-(4-aminocyclohexyl)-3-chloro-7-N-[4-(thiophene...)
Affinity DataIC50:  11nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17150(2-chloro-4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11441(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11435(4-({5-[(4-aminocyclohexyl)oxy]-3-(propan-2-yl)pyra...)
Affinity DataIC50:  17nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17151(2-imino-thiazolidin-4-one analog, 13 | 4-(5-{1-[(5...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11428(4-({5-[(4-aminocyclohexyl)amino]-3-(propan-2-yl)py...)
Affinity DataIC50:  59nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11433(4-[(5-{[4-(ethylamino)cyclohexyl]amino}-3-(propan-...)
Affinity DataIC50:  61nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17144(2-imino-thiazolidin-4-one analog, 6 | 4-(5-{[(5Z)-...)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11434(4-[(5-{[4-(diethylamino)cyclohexyl]amino}-3-(propa...)
Affinity DataIC50:  92nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17144(2-imino-thiazolidin-4-one analog, 6 | 4-(5-{[(5Z)-...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11453(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
Affinity DataIC50:  120nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11448(4-{[5-(cyclohexyloxy)-[1,2,4]triazolo[1,5-a]pyrimi...)
Affinity DataIC50:  140nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17141(2-imino-thiazolidin-4-one analog, 1 | 4-(5-{[(5Z)-...)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM11448(4-{[5-(cyclohexyloxy)-[1,2,4]triazolo[1,5-a]pyrimi...)
Affinity DataIC50:  190nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11443(5-chloro-N-(4-methanesulfonylphenyl)-3-(propan-2-y...)
Affinity DataIC50:  230nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17141(2-imino-thiazolidin-4-one analog, 1 | 4-(5-{[(5Z)-...)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11454(5-N-(4-aminocyclohexyl)-7-N-(4-methanesulfonylphen...)
Affinity DataIC50:  250nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11455(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)
Affinity DataIC50:  260nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11452(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
Affinity DataIC50:  270nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11448(4-{[5-(cyclohexyloxy)-[1,2,4]triazolo[1,5-a]pyrimi...)
Affinity DataIC50:  350nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11451(4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50:  400nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17151(2-imino-thiazolidin-4-one analog, 13 | 4-(5-{1-[(5...)
Affinity DataIC50:  430nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM17145(2-imino-thiazolidin-4-one analog, 7 | N-[2-(dimeth...)
Affinity DataIC50:  510nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17145(2-imino-thiazolidin-4-one analog, 7 | N-[2-(dimeth...)
Affinity DataIC50:  570nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17150(2-chloro-4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin...)
Affinity DataIC50:  570nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17149(2-imino-thiazolidin-4-one analog, 11 | 4-(5-{[(5Z)...)
Affinity DataIC50:  610nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11449(4-{[5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50:  730nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17153(4-(5-{[(4Z)-3-oxo-5-thia-2,7-diazatricyclo[6.4.0.0...)
Affinity DataIC50:  760nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM11452(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
Affinity DataIC50:  780nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Rattus norvegicus (rat))
Vernalis (R&D)

LigandPNGBDBM11449(4-{[5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a]pyri...)
Affinity DataIC50:  970nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified GSK-3 beta was incubated at room temperature with substrate, and test compounds in the presence of 10 uM ATP/ [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11438(N-(4-methanesulfonylphenyl)-5-(2-methylpropoxy)-3-...)
Affinity DataIC50:  1.20E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11437(N,N-dimethyl-4-{[5-(2-methylpropoxy)-3-(propan-2-y...)
Affinity DataIC50:  1.20E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA

Curated by ChEMBL
LigandPNGBDBM50288088(5,8-Dichloro-2-ethoxy-benzo[d][1,3]oxazin-4-one | ...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).More data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11444(5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1...)
Affinity DataIC50:  1.80E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11444(5-(3-bromophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1...)
Affinity DataIC50:  1.80E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11442(5-chloro-N-(4-methanesulfonylphenyl)pyrazolo[1,5-a...)
Affinity DataIC50:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11436(4-({5-[(3-aminocyclohexyl)amino]-3-(propan-2-yl)py...)
Affinity DataIC50:  2.10E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA

Curated by ChEMBL
LigandPNGBDBM50288091(2-(4-Methoxy-phenoxy)-benzo[d][1,3]oxazin-4-one | ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).More data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM17146((5Z)-2-imino-5-({5-[4-(piperazine-1-sulfonyl)pheny...)
Affinity DataIC50:  2.90E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11451(4-{[5-(diethylamino)-[1,2,4]triazolo[1,5-a]pyrimid...)
Affinity DataIC50:  3.40E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11455(5-N-(4-aminocyclohexyl)-7-N-[4-(benzenesulfonyl)ph...)
Affinity DataIC50:  4.30E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA

Curated by ChEMBL
LigandPNGBDBM50288097(CHEMBL81237 | [1-(2-Isopropylamino-4-oxo-4H-benzo[...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).More data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Vernalis (R&D)

LigandPNGBDBM11453(4-({5-[(4-aminocyclohexyl)amino]-[1,2,4]triazolo[1...)
Affinity DataIC50:  5.60E+3nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified CDK enzyme was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
TBA

Curated by ChEMBL
LigandPNGBDBM50288096(5-Chloro-2-ethoxy-benzo[d][1,3]oxazin-4-one | CHEM...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against herpes simplex type 1 protease (HSV-1 pr).More data for this Ligand-Target Pair
In DepthDetails Article
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