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Found 78 with Last Name = 'pierra' and Initial = 'c'
TargetAdenosine deaminase(Bos taurus (bovine))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50004352(CHEMBL14925 | [(2R,5S)-5-(6-Amino-purin-9-yl)-tetr...)
Affinity DataKi:  1.20E+5nMAssay Description:inhibitory activity against Adenosine deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534627(CHEMBL4527971)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534648(CHEMBL4463284)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534659(CHEMBL4464159)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534649(CHEMBL4451988)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534627(CHEMBL4527971)
Affinity DataIC50:  9nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534646(CHEMBL4567705)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  14nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534647(CHEMBL4522572)
Affinity DataIC50:  16nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  18nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  18.5nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534635(CHEMBL4464724)
Affinity DataIC50:  21nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  24nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534652(CHEMBL4471005)
Affinity DataIC50:  25nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534655(CHEMBL4441399)
Affinity DataIC50:  26nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534651(CHEMBL4548240)
Affinity DataIC50:  34nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM35554(thiophene scaffold, 21)
Affinity DataIC50:  35nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534645(CHEMBL4563132)
Affinity DataIC50:  46nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  52nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534632(CHEMBL4578396)
Affinity DataIC50:  59nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  75nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534637(CHEMBL4459000)
Affinity DataIC50:  81nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534658(CHEMBL4575406)
Affinity DataIC50:  118nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  119nMAssay Description:Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534642(CHEMBL4584994)
Affinity DataIC50:  135nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534639(CHEMBL4567123)
Affinity DataIC50:  147nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534657(CHEMBL4434914)
Affinity DataIC50:  154nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  160nMAssay Description:Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534631(CHEMBL4463960)
Affinity DataIC50:  170nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  181nMAssay Description:Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534656(CHEMBL4448379)
Affinity DataIC50:  189nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534652(CHEMBL4471005)
Affinity DataIC50:  197nMAssay Description:Inhibition of HCV genotype 4a1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534640(CHEMBL4529821)
Affinity DataIC50:  223nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426319(US10513534, Compound 407)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426317(US10513534, Compound 405)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426312(US10513534, Compound 401)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426315(US10513534, Compound 403)
Affinity DataIC50: <250nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C Virus (Virus))
Idenix Pharmaceuticals

US Patent
LigandPNGBDBM426318(US10513534, Compound 406)
Affinity DataIC50: <250nMAssay Description:Test compounds in the form of nucleoside triphosphates were examined for inhibitory activity against purified HCV polymerase in a standard assay. Bac...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534628(CHEMBL4441238)
Affinity DataIC50:  254nMAssay Description:Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534629(CHEMBL4444480)
Affinity DataIC50:  272nMAssay Description:Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534641(CHEMBL4465164)
Affinity DataIC50:  298nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534636(CHEMBL4474860)
Affinity DataIC50:  298nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534643(CHEMBL4454342)
Affinity DataIC50:  314nMAssay Description:Inhibition of HCV genotype 1b J4 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  335nMAssay Description:Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534630(CHEMBL4545438)
Affinity DataIC50:  335nMAssay Description:Inhibition of HCV genotype 3a NZL1 NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Idenix Sarl, An Msd

Curated by ChEMBL
LigandPNGBDBM50534650(CHEMBL4593826)
Affinity DataIC50:  337nMAssay Description:Inhibition of HCV genotype 2a JFH NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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