Affinity DataIC50: 0.130nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of biotinylated vitronectin from recombinant human integrin alphaVbeta3 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of PDGFRbeta (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of biotinylated vitronectin from human integrin alphaVbeta3 measured after 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Displacement of biotinylated vitronectin from recombinant human integrin alphaVbeta3 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Displacement of biotinylated vitronectin from recombinant human integrin alphaVbeta3 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.64nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10nMAssay Description:Displacement of biotinylated vitronectin from human integrin alphaVbeta3 measured after 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I] echistatin from alphaVbeta3 integrin isolated from human placenta after 3 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human PDGFRbeta expressed in insect cells using Ulight-Poly GAT[EAY(1:1:1)]n as substrate measured after 30 mins by LANCE m...More data for this Ligand-Target Pair
Affinity DataIC50: 15.1nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 18.9nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta5 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of biotinylated fibronectin from recombinant human integrin alpha5beta1 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32.6nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Displacement of [125I] echistatin from alphaVbeta3 integrin isolated from human placenta after 3 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGFR2 (unknown origin) phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Displacement of biotinylated fibronectin from recombinant human integrin alpha5beta1 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 101nMAssay Description:Displacement of biotinylated fibronectin from recombinant human integrin alpha5beta1 dark incubated for 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of alpha5beta1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Displacement of [125I]echistatin from integrin alphaVbeta3 receptor in human placenta by microplate scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 315nMAssay Description:Displacement of biotinylated vitronectin from human integrin alphaVbeta5 measured after 3 hrs by solid-phase receptor binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant human VEGFR2 expressed in Sf9 cells using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: 1.78E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...More data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of BACE1 (unknown origin) pre-incubated for 10 mins before addition of fluorescent substrate HiLyte FluorTM 488-Glu-Val-Asn-Leu-Asp-Ala-Gl...More data for this Ligand-Target Pair
Affinity DataIC50: 3.47E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: 4.38E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: 4.96E+3nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of vitronectin binding to alphaVbeta3 in human EPC in presence of MnCl2 measured after 30 mins by crystal violet staining based cell adhes...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta3More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]echistatin from human integrin alphaVbeta5More data for this Ligand-Target Pair