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Found 37 with Last Name = 'quirion' and Initial = 'r'
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50453179(CHEMBL2369463)
Affinity DataIC50:  0.5nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50453179(CHEMBL2369463)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000750(CHEMBL2369459 | [Val-Ala-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000750(CHEMBL2369459 | [Val-Ala-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50453179(CHEMBL2369463)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000743(CHEMBL525571 | [Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Se...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000750(CHEMBL2369459 | [Val-Ala-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  2.40nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000747(CHEMBL2369454 | [Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-S...)
Affinity DataIC50:  3nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000749(CHEMBL2369458 | [Val-Thr-His-Arg-Ala-Ala-Gly-Leu-L...)
Affinity DataIC50:  8nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027791(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataIC50:  8nMAssay Description:Ability to induce 50% of maximal effect in mouse vas deferens expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000749(CHEMBL2369458 | [Val-Thr-His-Arg-Ala-Ala-Gly-Leu-L...)
Affinity DataIC50:  8nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000749(CHEMBL2369458 | [Val-Thr-His-Arg-Ala-Ala-Gly-Leu-L...)
Affinity DataIC50:  8nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataIC50:  8.40nMAssay Description:Ability to displace 50% of (+/-) ethylketocyclazocine (2.8) in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50027790(3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  8.60nMAssay Description:Ability to induce 50% of maximal effect in mouse vas deferens expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000742(CHEMBL2369452 | [His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-A...)
Affinity DataIC50:  9nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000742(CHEMBL2369452 | [His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-A...)
Affinity DataIC50:  9nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000742(CHEMBL2369452 | [His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-A...)
Affinity DataIC50:  9nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
TBA

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataIC50:  9.40nMAssay Description:Ability to induce 50% of maximal effect in mouse vas deferens expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50027791(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataIC50:  9.80nMAssay Description:Ability to induce 50% of maximal effect in guinea pig ileum expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000747(CHEMBL2369454 | [Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-S...)
Affinity DataIC50:  11nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000746(CHEMBL2369457 | [Val-Thr-His-Ala-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  11nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000747(CHEMBL2369454 | [Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-S...)
Affinity DataIC50:  12nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50027790(3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  12nMAssay Description:Ability to induce 50% of maximal effect in guinea pig ileum expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000746(CHEMBL2369457 | [Val-Thr-His-Ala-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  14.5nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000746(CHEMBL2369457 | [Val-Thr-His-Ala-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  15nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000744(CHEMBL2369464 | [Val-Thr-Ala-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  20nMAssay Description:Binding affinity of the compound against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig vas deferens membrane prep...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000744(CHEMBL2369464 | [Val-Thr-Ala-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  20.2nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000744(CHEMBL2369464 | [Val-Thr-Ala-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  20.2nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rattus norvegicus)
Université

Curated by ChEMBL
LigandPNGBDBM50000745(CHEMBL2369465 | [Val-Thr-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  21.9nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type alpha receptor binding sites in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000745(CHEMBL2369465 | [Val-Thr-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  22nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50000745(CHEMBL2369465 | [Val-Thr-His-Arg-Leu-Ala-Gly-Leu-L...)
Affinity DataIC50:  25nMAssay Description:Binding affinity against [125I]-hCalcitonin gene-related peptide type receptor binding sites in guinea pig atrium membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataIC50:  47nMAssay Description:Ability to induce 50% of maximal effect in rabbit vas deferens expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  77nMAssay Description:Ability to induce 50% of maximal effect in guinea pig ileum expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027791(6,11-Dimethyl-3-phenethyl-1,2,3,4,5,6-hexahydro-2,...)
Affinity DataIC50:  121nMAssay Description:Ability to induce 50% of maximal effect in rabbit vas deferens expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50027790(3,5-Dibromo-2-hydroxy-N-(3-trifluoromethyl-phenyl)...)
Affinity DataIC50:  157nMAssay Description:Ability to induce 50% of maximal effect in rabbit vas deferens expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed