Compile Data Set for Download or QSAR
maximum 50k data
Found 389 with Last Name = 'rankine' and Initial = 'n'
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414644(CHEMBL555122)
Affinity DataIC50:  1.26nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414643(CHEMBL557455)
Affinity DataIC50:  2nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414641(CHEMBL554065)
Affinity DataIC50:  2nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414636(CHEMBL559880)
Affinity DataIC50:  2.51nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414640(CHEMBL562844)
Affinity DataIC50:  3.16nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414641(CHEMBL554065)
Affinity DataIC50:  3.98nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414638(CHEMBL549378)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414639(CHEMBL550872)
Affinity DataIC50:  5.01nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414642(CHEMBL549791)
Affinity DataIC50:  6.31nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414639(CHEMBL550872)
Affinity DataIC50:  6.31nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414638(CHEMBL549378)
Affinity DataIC50:  6.31nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414642(CHEMBL549791)
Affinity DataIC50:  7.94nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50:  7.94nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296598((R)-2-(2,4-dichlorophenylsulfonamido)-3-(thiophene...)
Affinity DataIC50:  8nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296610((R)-3-(1-methyl-1H-pyrazole-5-carboxamido)-2-(2,4,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM31992(Dipeptidyl nitrile inhibitor, 25)
Affinity DataIC50:  12.6nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50:  12.6nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31993(Dipeptidyl nitrile inhibitor, 26)
Affinity DataIC50:  13nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31992(Dipeptidyl nitrile inhibitor, 25)
Affinity DataIC50:  13nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003386(2-Ethyl-5-methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  13nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414637(CHEMBL562915)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414638(CHEMBL549378)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414629(CHEMBL563471)
Affinity DataIC50:  15.8nMAssay Description:Inhibition of cathepsin L assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003392(2-Methyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296635((R)-2-(2,3-dichlorophenylsulfonamido)-3-(thiophene...)
Affinity DataIC50:  19nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414635(CHEMBL564626)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414637(CHEMBL562915)
Affinity DataIC50:  19.9nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31984(Dipeptidyl nitrile inhibitor, 17)
Affinity DataIC50:  20nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003400(2-Ethyl-6-methoxy-4-[2'-(1H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296597((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trichloro...)
Affinity DataIC50:  24nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296603((R)-3-benzamido-2-(2-iodophenylsulfonamido)propano...)
Affinity DataIC50:  25nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414636(CHEMBL559880)
Affinity DataIC50:  25.1nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003377(2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003403(2-Ethyl-6-isopropoxy-4-[2'-(1H-tetrazol-5-yl)-biph...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003387(2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296611((R)-3-(furan-3-carboxamido)-2-(2,4,6-trimethylphen...)
Affinity DataIC50:  32nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414643(CHEMBL557455)
Affinity DataIC50:  39.8nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003394(2-Methyl-4-{1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296609((R)-3-(2-methyloxazole-4-carboxamido)-2-(2,4,6-tri...)
Affinity DataIC50:  41nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296612((R)-3-(thiophene-3-carboxamido)-2-(2,4,6-trimethyl...)
Affinity DataIC50:  44nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31980(Dipeptidyl nitrile inhibitor, 13)
Affinity DataIC50:  50nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(Cavia porcellus)
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50003376(2-Ethyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmeth...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296600((R)-3-benzamido-2-(2,3-dichlorophenylsulfonamido)p...)
Affinity DataIC50:  62nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L [114-333,T223A](Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM31990(Dipeptidyl nitrile inhibitor, 23)
Affinity DataIC50:  63nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50296607((R)-3-(pyrimidine-5-carboxamido)-2-(2,4,6-trimethy...)
Affinity DataIC50:  63nMAssay Description:Inhibition of fibrinogen binding to alphavbeta3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414642(CHEMBL549791)
Affinity DataIC50:  63.1nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414644(CHEMBL555122)
Affinity DataIC50:  63.1nMAssay Description:Inhibition of cathepsin S assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414633(CHEMBL556436)
Affinity DataIC50:  63.1nMAssay Description:Inhibition of cathepsin L2 assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50414639(CHEMBL550872)
Affinity DataIC50:  63.1nMAssay Description:Inhibition of cathepsin K assessed as inhibition of fluorogenic substrate cleavageMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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