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Found 51 with Last Name = 'rodriguez' and Initial = 'de'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162556(6,7-Dichloro-2-isopropyl-5-[3-(pyridin-4-ylsulfany...)
Affinity DataEC50:  839nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170327(1-(2,2-Dimethyl-propyl)-4-propyl-5-{5-[4-(1H-tetra...)
Affinity DataEC50:  1.01E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162557((+/-)-4-(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo...)
Affinity DataEC50:  892nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162559(6,7-Dimethyl-2-propyl-5-[3-(pyridin-4-ylsulfanylme...)
Affinity DataEC50:  291nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162560(CHEMBL369526 | N-[4-(6,7-Dichloro-2-cyclopentyl-2-...)
Affinity DataEC50:  515nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162561(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(2H-tetra...)
Affinity DataEC50:  5.00E+3nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162562(6,7-Dichloro-2-methyl-2-phenyl-5-[4-(2H-tetrazol-5...)
Affinity DataEC50:  629nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162563(6,7-Dichloro-2-cyclopentyl-2-methyl-5-{3-[4-(2H-te...)
Affinity DataEC50:  270nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162564(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[4-(2H-tetra...)
Affinity DataEC50:  589nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162565(6,7-Dichloro-2-propyl-5-[3-(pyridin-4-ylsulfanylme...)
Affinity DataEC50:  186nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162567(6,7-Dichloro-2-cyclopentyl-2-methyl-5-{2-[4-(2H-te...)
Affinity DataEC50:  1.16E+3nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162566(6,7-Dichloro-2-propyl-5-[4-(2H-tetrazol-5-yl)-benz...)
Affinity DataEC50:  282nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162568(6,7-Dichloro-2-cyclopentyl-5-[4-(2H-tetrazol-5-yl)...)
Affinity DataEC50:  122nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162570(2-(6,7-Dichloro-2-cyclopentyl-2-methyl-1-oxo-indan...)
Affinity DataEC50:  600nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162569(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[4-(2H-tetra...)
Affinity DataEC50:  223nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162573(6,7-Dichloro-2-isopropyl-5-[4-(2H-tetrazol-5-yl)-b...)
Affinity DataEC50:  195nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162571(CHEMBL180455 | N-Acetyl-4-(6,7-dichloro-2-cyclopen...)
Affinity DataEC50:  442nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162572(6,7-Dichloro-2-cyclopentyl-5-[3-(pyridin-4-ylsulfa...)
Affinity DataEC50:  165nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162577(6,7-Dichloro-2-cyclopentyl-2-methyl-5-{2-[4-(2H-te...)
Affinity DataEC50:  276nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162575(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(pyridin-...)
Affinity DataEC50:  562nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162576(2-Butyl-6,7-dichloro-2-cyclopentyl-5-[4-(2H-tetraz...)
Affinity DataEC50:  1.09E+3nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162574(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[3-(2H-tetra...)
Affinity DataEC50:  371nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162579(2-Cyclopentyl-6,7-dimethyl-5-[3-(pyridin-4-ylsulfa...)
Affinity DataEC50:  596nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162578(6,7-Dichloro-2,2-dimethyl-5-[4-(2H-tetrazol-5-yl)-...)
Affinity DataEC50:  782nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50162580(6,7-Dichloro-2-cyclopentyl-2-methyl-5-[5-(2H-tetra...)
Affinity DataEC50:  761nMAssay Description:Binding affinity against metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170306(1-(2,2-Dimethyl-propyl)-4-propyl-5-[4'-(1H-tetrazo...)
Affinity DataEC50:  318nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170307(3-(2,2-Dimethyl-propyl)-7-propyl-6-{4-[4-(1H-tetra...)
Affinity DataEC50:  788nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170308(1-(2,2-Dimethyl-propyl)-5-{4-[4-(1H-tetrazol-5-yl)...)
Affinity DataEC50:  3.59E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170309(1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...)
Affinity DataEC50:  134nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170310(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  984nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170312(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  936nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 expressed in HEK293 cells done for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170311(1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-b...)
Affinity DataEC50:  652nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170313(4-Bromo-1-(2,2-dimethyl-propyl)-5-{4-[4-(1H-tetraz...)
Affinity DataEC50:  2.26E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170314(1-(2,2-Dimethyl-propyl)-4-methyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  1.07E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170315(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  1.17E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170317(1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...)
Affinity DataEC50:  451nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170316(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  879nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170319(1-Pentyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-pheno...)
Affinity DataEC50:  598nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170318(1-(2,2-Dimethyl-propyl)-2-methyl-4-propyl-5-{4-[4-...)
Affinity DataEC50:  559nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170320(1-Isopropyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-ph...)
Affinity DataEC50:  1.13E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170321(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  779nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153757(1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...)
Affinity DataEC50:  348nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170322(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  6.37E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170323(1-(2,2-Dimethyl-propyl)-4-propyl-5-{2-[4-(1H-tetra...)
Affinity DataEC50:  1.36E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170312(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  188nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170325(1-Cyclopropylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-...)
Affinity DataEC50:  755nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170324(1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5...)
Affinity DataEC50:  228nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170328(1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...)
Affinity DataEC50:  3.54E+3nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170329(1-Isobutyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phe...)
Affinity DataEC50:  765nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50170326(1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...)
Affinity DataEC50:  559nMAssay Description:Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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