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Found 136 with Last Name = 'rogers' and Initial = 'mj'
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373094(CHEMBL408608)
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098390((3-methylpyridin-2-ylamino)methylenediphosphonic a...)
Affinity DataKi:  1.09nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373098(CHEMBL259729)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115104((pyridin-2-ylamino)methylenediphosphonic acid | 2-...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373097(CHEMBL406820)
Affinity DataKi:  3.28nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792(2-(2-aminophenyl)-1-hydroxyethane-1,1-diyldiphosph...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12577(Bisphosphonate 2 | CHEMBL997 | JMC515594 Compound ...)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119489(1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic a...)
Affinity DataKi:  4nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119488(CHEMBL143628 | X1-(4-Chloro-phenyl)-1H-pyrazole-3,...)
Affinity DataKi:  4nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373096(CHEMBL99369 | Piridronic acid)
Affinity DataKi:  4.45nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119481(1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic a...)
Affinity DataKi:  6nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)
Affinity DataKi:  7.40nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119483(1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic a...)
Affinity DataKi:  8nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115115((Cyclohexylamino-phosphono-methyl)-phosphonic acid...)
Affinity DataKi:  10nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373093(CHEMBL100154)
Affinity DataKi:  11.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119485(1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...)
Affinity DataKi:  12nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098390((3-methylpyridin-2-ylamino)methylenediphosphonic a...)
Affinity DataKi:  12.1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119490(1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...)
Affinity DataKi:  26nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115104((pyridin-2-ylamino)methylenediphosphonic acid | 2-...)
Affinity DataKi:  29.1nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119492(1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic a...)
Affinity DataKi:  32nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50138725((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...)
Affinity DataKi:  34.8nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115106(2-(pyridin-2-ylamino)ethane-1,1-diyldiphosphonic a...)
Affinity DataKi:  36.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373096(CHEMBL99369 | Piridronic acid)
Affinity DataKi:  39.0nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM25313((4-amino-1-hydroxy-1-phosphonobutyl)phosphonic aci...)
Affinity DataKi:  44.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataKi:  48.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12581((3-amino-1-hydroxy-1-phosphonopropyl)phosphonic ac...)
Affinity DataKi:  55.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098378((1-Hydroxy-1-phosphono-2-pyridin-2-yl-ethyl)-phosp...)
Affinity DataKi:  59.3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50115115((Cyclohexylamino-phosphono-methyl)-phosphonic acid...)
Affinity DataKi:  62.4nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098383((6-amino-1-hydroxy-1-phosphono-hexyl)-phosphonic a...)
Affinity DataKi:  63.5nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50173792(2-(2-aminophenyl)-1-hydroxyethane-1,1-diyldiphosph...)
Affinity DataKi:  64.6nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098382((1-Hydroxy-1-phosphono-3-pyridin-3-yl-propyl)-phos...)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12576(Bisphosphonate 1 | CHEMBL923 | JMC515594 Compound ...)
Affinity DataKi:  82.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)
Affinity DataKi:  85.9nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373094(CHEMBL408608)
Affinity DataKi:  86.3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119487(1-(4-Chloro-phenyl)-1H-pyrazole-3,5-dicarboxylic a...)
Affinity DataKi:  91nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373097(CHEMBL406820)
Affinity DataKi:  112nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373098(CHEMBL259729)
Affinity DataKi:  137nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50119491(1-(4-Methoxy-phenyl)-1H-pyrazole-3,5-dicarboxylic ...)
Affinity DataKi:  138nMAssay Description:Inhibition of dihydroorotate dehydrogenase (DHODase) of Helicobacter pyloriMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373095(CHEMBL98719)
Affinity DataKi:  155nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373099(CHEMBL99553 | NE-10575)
Affinity DataKi:  177nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataKi:  194nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12577(Bisphosphonate 2 | CHEMBL997 | JMC515594 Compound ...)
Affinity DataKi:  195nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373095(CHEMBL98719)
Affinity DataKi:  196nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM12579((1-hydroxy-2-phenyl-1-phosphonoethyl)phosphonic ac...)
Affinity DataKi:  303nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50373093(CHEMBL100154)
Affinity DataKi:  320nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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