Compile Data Set for Download or QSAR
maximum 50k data
Found 735 with Last Name = 'rong' and Initial = 'h'
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  670nM ΔG°:  -35.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  690nM ΔG°:  -35.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  700nM ΔG°:  -35.7kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  1.10E+3nM ΔG°:  -34.6kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))
Affinity DataKi:  1.24E+3nM ΔG°:  -34.3kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM22231((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...)
Affinity DataKi:  1.26E+3nM ΔG°:  -34.2kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM50269531((9Z)-hexadec-9-enoic acid | (Z)-9-hexadecenoic aci...)
Affinity DataKi:  1.36E+3nM ΔG°:  -34.0kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50269531((9Z)-hexadec-9-enoic acid | (Z)-9-hexadecenoic aci...)
Affinity DataKi:  1.64E+3nM ΔG°:  -33.6kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50269531((9Z)-hexadec-9-enoic acid | (Z)-9-hexadecenoic aci...)
Affinity DataKi:  1.78E+3nM ΔG°:  -33.4kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM22231((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...)
Affinity DataKi:  2.17E+3nM ΔG°:  -32.9kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Emory University

LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataKi:  2.59E+3nM ΔG°:  -32.4kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM50152850(1-HEXYLDECANOIC ACID | CHEMBL82293 | Hexadecanoic ...)
Affinity DataKi:  3.06E+3nM ΔG°:  -32.0kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM22231((9Z,12Z)-octadeca-9,12-dienoic acid | CHEMBL267476...)
Affinity DataKi:  3.47E+3nM ΔG°:  -31.7kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
TargetFatty acid-binding protein 5 [M35A,L60A](Homo sapiens (Human))
Emory University

LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataKi:  5.01E+3nM ΔG°:  -30.8kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5 [K24A,R33A,K34A](Homo sapiens (Human))
Emory University

LigandPNGBDBM22319((5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | ...)
Affinity DataKi:  9.37E+3nM ΔG°:  -29.2kJ/molepH: 8.2 T: 2°CAssay Description:In brief, both wild-type and mutant hFABP5 were expressed and purified to homogeneity as described above and dialyzed in PBS (pH 8.2). Binding affini...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232534(5-((2-fluorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232526(5-((2,4-difluorophenoxy)methyl)quinazoline-2,4-dia...)
Affinity DataIC50:  0.0200nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237216(CHEMBL4080254)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232538(5-((1-(2-fluorobenzyl)piperidin-4-yl)methoxy)quina...)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237201(CHEMBL4082618)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50232589(5-((3-chlorophenoxy)methyl)quinazoline-2,4-diamine...)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237200(CHEMBL4072132)
Affinity DataIC50:  0.0690nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM36530(D157493)
Affinity DataIC50:  0.0800nMAssay Description:Binding affinity towards 5-HT3 receptor in rat was evaluatedMore data for this Ligand-Target Pair
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237199(CHEMBL4077061)
Affinity DataIC50:  0.110nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237203(CHEMBL250072)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237205(CHEMBL398675)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237209(CHEMBL4062544)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237211(CHEMBL4061457)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50237210(CHEMBL399673)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359073(CHEMBL1922653)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50205166(CHEMBL231636 | N-((2S,3S)-4-(4-chlorophenyl)-3-(3-...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Targetm7GpppX diphosphatase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM36534(D156095)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of human DcpS assessed as increase in SMN2 promoter activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359075(CHEMBL1922655)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359076(CHEMBL1922656)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359077(CHEMBL1922657)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359083(CHEMBL1922663)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50015453(CHEMBL3265037)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of full length Syk (unknown origin) using biotinylated peptide substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359062(CHEMBL1922642)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297385(3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359082(CHEMBL1922662)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359085(CHEMBL1922665)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029559(2-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qui...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359079(CHEMBL1922659)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359078(CHEMBL1922658)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359061(CHEMBL1922532)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359086(CHEMBL1922666)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [3H]-3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzylindol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359063(CHEMBL1922643)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359088(CHEMBL1229205)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359081(CHEMBL1922661)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 10 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 735 total ) | Next | Last >>
Jump to: