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Found 96 with Last Name = 'rubins' and Initial = 'k'
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50073630(2,3-Bis-[(E)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]...)
Affinity DataIC50:  130nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50073630(2,3-Bis-[(E)-3-(3,4-dihydroxy-phenyl)-acryloyloxy]...)
Affinity DataIC50:  150nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50056908((1R,3R,4S,5R)-3,4-Bis-[(E)-3-(3,4-dihydroxy-phenyl...)
Affinity DataIC50:  250nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50056908((1R,3R,4S,5R)-3,4-Bis-[(E)-3-(3,4-dihydroxy-phenyl...)
Affinity DataIC50:  250nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088352(4-Dimethylamino-3,6,12-trihydroxy-6,10-dimethyl-1,...)
Affinity DataIC50:  300nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088252(3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-4,4',7,7...)
Affinity DataIC50:  350nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50056908((1R,3R,4S,5R)-3,4-Bis-[(E)-3-(3,4-dihydroxy-phenyl...)
Affinity DataIC50:  460nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50056908((1R,3R,4S,5R)-3,4-Bis-[(E)-3-(3,4-dihydroxy-phenyl...)
Affinity DataIC50:  460nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088358(4-Dimethylamino-3,6,12-trihydroxy-6,10-dimethyl-1,...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  600nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  600nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088359(3,5-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4...)
Affinity DataIC50:  640nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088359(3,5-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-1,4...)
Affinity DataIC50:  660nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088356(1,3-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-4,5...)
Affinity DataIC50:  680nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088352(4-Dimethylamino-3,6,12-trihydroxy-6,10-dimethyl-1,...)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  900nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088349(2',3,3',4,4'-pentahydroxychalcone | 3-(3,4-Dihydro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50077360(3,10-Dihydroxy-13-(3-hydroxy-4-methoxy-phenyl)-2,1...)
Affinity DataIC50:  1.00E+3nMAssay Description:The compound was tested in vitro for inhibition of HIV-1 replicationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088353(5-(3,4-Dihydroxy-phenyl)-3-hydroxy-pentanoic acid ...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088356(1,3-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-4,5...)
Affinity DataIC50:  1.08E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088358(4-Dimethylamino-3,6,12-trihydroxy-6,10-dimethyl-1,...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088350(CHEMBL430786 | Sodium; 1-[N'-(4-dimethylamino-3,6,...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM23408(2-(3,4-dihydroxyphenyl)-3,5,6,7-tetrahydroxy-4H-ch...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088252(3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-4,4',7,7...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088353(5-(3,4-Dihydroxy-phenyl)-3-hydroxy-pentanoic acid ...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088349(2',3,3',4,4'-pentahydroxychalcone | 3-(3,4-Dihydro...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088251(4,4',7,7'-tetrabromo-3,3,3',3'-tetramethyl-1,1'-sp...)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088250(3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088360(2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one | 2,...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088355(10-(4-Amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  2.40E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088250(3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM5149((2E)-2-cyano-N-{3-[(2E)-2-cyano-3-(3,4-dihydroxyph...)
Affinity DataIC50:  3.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088249(5,5'-diiodo-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3...)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088251(4,4',7,7'-tetrabromo-3,3,3',3'-tetramethyl-1,1'-sp...)
Affinity DataIC50:  3.14E+3nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088350(CHEMBL430786 | Sodium; 1-[N'-(4-dimethylamino-3,6,...)
Affinity DataIC50:  3.60E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088252(3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-4,4',7,7...)
Affinity DataIC50:  4.00E+3nMAssay Description:Tested in vitro against strand -transfer (ST) activity in the presence of Mg2+ as the cationic cofactorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50041419(1,2,5,8-tetrahydroxy-9,10-anthracenedione | 1,2,5,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088355(10-(4-Amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088255(3,3,3',3'-tetramethyl-1,1'-spirobi[2,3-dihydro-1H-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088357(CHEMBL68073 | Tetramethyl-silane)
Affinity DataIC50:  5.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088256(6,6'-dihydroxy-3,3,3',3'-tetramethyl-1,1'-spirobi[...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of strand -transfer (ST) activity in the presence of Mn2+More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088249(5,5'-diiodo-3,3,3',3'-tetramethyl-1,1'-spirobi[2,3...)
Affinity DataIC50:  6.28E+3nMAssay Description:Inhibition of 3'-processing (TC) in the presence of Mn2+ in vitro More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088347(1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5...)
Affinity DataIC50:  7.80E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM67690(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)
Affinity DataIC50:  8.00E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50077357(14-(3-hydroxy-4-methoxyphenyl)-2,11,12-trimethoxy-...)
Affinity DataIC50:  8.00E+3nMAssay Description:The compound was tested in vitro for inhibition of HIV-1 replicationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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