Affinity DataKi: 0.0100nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of NAALADase activity in human LNCaP cell membranes assessed as inhibition of [3H]NAG conversion to [3H]glutamate after 30 mins by liquid ...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.09nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [125I]ET1 from endothelin B receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.26nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Inhibition of NAALADase activity in human LNCaP cell membranes assessed as inhibition of [3H]NAG conversion to [3H]glutamate after 30 mins by liquid ...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 1.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.43nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Inhibition of NAALADase activity in human LNCaP cell membranes assessed as inhibition of [3H]NAG conversion to [3H]glutamate after 30 mins by liquid ...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Inhibition of NAALADase activity in human LNCaP cell membranes assessed as inhibition of [3H]NAG conversion to [3H]glutamate after 30 mins by liquid ...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 7.30nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.90nMAssay Description:Displacement of [125I]ET1 from ETA receptor in CD1 Nu/Nu mouse myocardial ventricles membranes after 2 hrs by gamma countingMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 8.30nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 8.60nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 9.80nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 12.6nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of human recombinant caspase-3 assessed as Ac-DEVD-AMC conversion to 7-amino-4-methylcoumarin incubated for 10 mins prior to substrate add...More data for this Ligand-Target Pair
Affinity DataKi: 16.1nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
Affinity DataKi: 16.2nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 17.9nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Inhibition of NAALADase activity in human LNCaP cell membranes assessed as inhibition of [3H]NAG conversion to [3H]glutamate after 30 mins by liquid ...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
Affinity DataKi: 23nMAssay Description:Binding affinity to NAALADaseMore data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
University Hospital Of The WestfäLische Wilhelms-UniversitäT
Curated by ChEMBL
Affinity DataKi: 23.5nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I]ET1 from endothelin A receptor in DBA mouse microsomesMore data for this Ligand-Target Pair