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Found 496 with Last Name = 'schamberger' and Initial = 'j'
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189812(US9174997, 10)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189921(US9174997, 141)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189908(US9174997, 128)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189924(US9174997, 144)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189813(US9174997, 12)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189814(US9174997, 14)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189815(US9174997, 18)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189818(US9174997, 27)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189819(US9174997, 32)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189820(US9174997, 33)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189821(US9174997, 36)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189822(US9174997, 41)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189823(US9174997, 43 (Diastereomer 1))
Affinity DataIC50:  0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189831(US9174997, 51)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189835(US9174997, 55)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189860(US9174997, 80)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189865(US9174997, 85)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189871(US9174997, 91)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189876(US9174997, 96)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189883(US9174997, 103)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189896(US9174997, 116)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189900(US9174997, 120)
Affinity DataIC50: <0.300nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189817(US9174997, 22)
Affinity DataIC50:  0.450nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189811(US9174997, 6)
Affinity DataIC50:  0.5nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189849(US9174997, 69)
Affinity DataIC50:  0.900nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256099(US9481672, 281)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255968(US9481672, 146)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256036(US9481672, 217)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256064(US9481672, 246)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256065(US9481672, 247)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255962(US9481672, 140)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255964(US9481672, 142)
Affinity DataIC50:  1nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189912(US9174997, 132)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189830(US9174997, 50)
Affinity DataIC50:  1.60nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM88376(US9695131, 13)
Affinity DataIC50:  1.80nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM189816(US9174997, 20)
Affinity DataIC50:  1.90nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255973(US9481672, 151)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255971(US9481672, 149)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256116(US9481672, 300)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256111(US9481672, 294)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255969(US9481672, 147)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256088(BDBM256092 | BDBM256093 | US9481672, 270)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM256095(US9481672, 277)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255967(US9481672, 145)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255966(US9481672, 144)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255965(US9481672, 143)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255963(US9481672, 141)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255961(US9481672, 139)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255958(US9481672, 136)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Targetchymase(Mesocricetus auratus (Golden hamster))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM255956(US9481672, 134)
Affinity DataIC50:  2nMpH: 7.5Assay Description:The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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