Compile Data Set for Download or QSAR
maximum 50k data
Found 548 with Last Name = 'sengupta' and Initial = 'd'
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374104(CHEMBL255962)
Affinity DataKi:  0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374100(CHEMBL270011)
Affinity DataKi:  0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50232355((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374110(CHEMBL401954)
Affinity DataKi:  0.0800nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50232355((3aR,6aR)-2-(cyclopropylmethyl)-6-(4-(2-(pyrrolidi...)
Affinity DataKi:  0.100nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374102(CHEMBL402297)
Affinity DataKi:  0.160nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374109(CHEMBL255840)
Affinity DataKi:  0.290nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374095(CHEMBL255752)
Affinity DataKi:  0.300nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374101(CHEMBL410623)
Affinity DataKi:  0.400nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374098(CHEMBL256225)
Affinity DataKi:  0.400nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374103(CHEMBL255961)
Affinity DataKi:  0.510nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374111(CHEMBL409899)
Affinity DataKi:  0.75nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374107(CHEMBL270440)
Affinity DataKi:  0.900nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374097(CHEMBL255166)
Affinity DataKi:  1.70nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374105(CHEMBL429418)
Affinity DataKi:  2nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374108(CHEMBL273202)
Affinity DataKi:  2.30nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374099(CHEMBL256648)
Affinity DataKi:  2.40nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374094(CHEMBL402296)
Affinity DataKi:  2.80nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374112(CHEMBL258302)
Affinity DataKi:  7nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374113(CHEMBL255847)
Affinity DataKi:  36nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374096(CHEMBL404753)
Affinity DataKi:  58nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM27193((1R,2S,5S,6S,9R,12S,13R,16S)-N,N,6,7,13-pentamethy...)
Affinity DataKi:  66nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374106(CHEMBL270439)
Affinity DataKi:  67nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374092(CHEMBL437404)
Affinity DataKi:  256nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50374093(CHEMBL270241)
Affinity DataKi:  310nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50041691(CHEMBL3358920 | US11149292, Compound (R)-2-(7-(4-c...)
Affinity DataIC50:  1.90nMAssay Description:Induction of internalization of HA-tagged human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302559(CHEMBL578049 | N-(cis-4-{[4-(Dimethylamino)-5-meth...)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302561(CHEMBL568208 | N-((cis)-4-(4-(dimethylamino)-5,6-d...)
Affinity DataIC50:  2.30nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302552(CHEMBL578166 | N-((cis)-4-(4-(dimethylamino)-6-met...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302555(CHEMBL567993 | N-((cis)-4-(4-(dimethylamino)-5-met...)
Affinity DataIC50:  2.90nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302569(3,5-dichloro-N-(((cis)-4-(4-(dimethylamino)-5-meth...)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302553(3,4-dichloro-N-((cis)-4-(4-(dimethylamino)-6-methy...)
Affinity DataIC50:  4.80nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302568(CHEMBL566075 | N-[(cis-4-{[4-(Dimethylamino)-5-met...)
Affinity DataIC50:  5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50150715(4''-Fluoro-biphenyl-4-carboxylic acid (6-dimethyla...)
Affinity DataIC50:  5.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302557(CHEMBL565551 | N-((cis)-4-(4-(dimethylamino)-5-met...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302548(3-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyr...)
Affinity DataIC50:  6.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(CHEMBL182150 | N-((cis)-4-(4-(dimethylamino)quinaz...)
Affinity DataIC50:  7.20nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302551(CHEMBL567950 | N-((cis)-4-(4-(dimethylamino)-6-met...)
Affinity DataIC50:  7.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302554(CHEMBL583014 | N-((cis)-4-(4-(dimethylamino)-6-met...)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302546(CHEMBL568162 | N-((cis)-4-(4-(dimethylamino)-6-met...)
Affinity DataIC50:  9.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(CHEMBL182150 | N-((cis)-4-(4-(dimethylamino)quinaz...)
Affinity DataIC50:  9.66nMAssay Description:Displacement of [125I]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302558(4-chloro-N-((cis)-4-(4-(dimethylamino)-5-methylpyr...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302556(CHEMBL578170 | N-((cis)-4-(4-(dimethylamino)-5-met...)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302547(4-chloro-N-((cis)-4-(4-(dimethylamino)-6-methylpyr...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170191(CHEMBL182150 | N-((cis)-4-(4-(dimethylamino)quinaz...)
Affinity DataIC50:  16.9nMAssay Description:Inhibition of human 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302549(CHEMBL568664 | N-((cis)-4-(4-(dimethylamino)-6-met...)
Affinity DataIC50:  25nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302565(CHEMBL577913 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302555(CHEMBL567993 | N-((cis)-4-(4-(dimethylamino)-5-met...)
Affinity DataIC50:  31nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302570(CHEMBL568649 | N-((cis)-4-(4-(ethyl(methyl)amino)-...)
Affinity DataIC50:  46nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302562(CHEMBL568209 | N-((cis)-4-(4,6-bis(dimethylamino)p...)
Affinity DataIC50:  58nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 548 total ) | Next | Last >>
Jump to: