Affinity DataKi: 0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 66nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 67nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 256nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Displacement of N-[3H]methylhistamine from histamine H3 receptor in rat cortexMore data for this Ligand-Target Pair
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Induction of internalization of HA-tagged human S1P1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 9.66nMAssay Description:Displacement of [125I]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 16.9nMAssay Description:Inhibition of human 5HT1AMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]rauwolsine from human 5HT2B receptorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by ChEMBL
Arena Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...More data for this Ligand-Target Pair