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Found 27 with Last Name = 'siciliano' and Initial = 'r'
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.530nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089073(({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  720nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089075(2-({1-[2-({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  1.44E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089071(({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataKi:  1.62E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089072(2-({1-[2-({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataKi:  7.54E+3nMAssay Description:Compound was evaluated for the binding affinity of Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50035696(1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...)
Affinity DataIC50:  6nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  53nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192468(CHEMBL3923282)
Affinity DataIC50:  64nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192651(CHEMBL3980379)
Affinity DataIC50:  131nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192646(CHEMBL3916038)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089073(({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089075(2-({1-[2-({1-[3-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089071(({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of 12G5 anti-CXCR4 antibody binding to CXCR4 in human HT29 cells preincubated for 30 mins followed by antibody addition by FACS Canto II c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192650(CHEMBL3981298)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192645(CHEMBL3952526)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192652(CHEMBL3901189)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192647(CHEMBL3977069)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192643(CHEMBL3951019)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192642(CHEMBL3924369)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192648(CHEMBL3942287)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192644(CHEMBL3914285)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192641(CHEMBL3933305)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192640(CHEMBL3927148)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192649(CHEMBL3896351)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Second University Of Naples

Curated by ChEMBL
LigandPNGBDBM50192653(CHEMBL3906404)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PE-conjugated-12G5 anti-CXCR4 antibody binding to CXCR4 in human CEM-CCRF cells preincubated for 30 mins followed by antibody addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50089072(2-({1-[2-({1-[2-({1-[2-Amino-3-(4-hydroxy-phenyl)-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory concentration against [3H]DAMGO binding to Opioid receptor mu 1 in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed