Affinity DataKi: 1.30nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Binding affinity to insulin receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-LY459477 from human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Binding affinity to IGF1R by liquid scintillation countingMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 7.40nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 7.70nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 8.90nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 9.40nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 166nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of [3H]-LY459477 from human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing human EAAT1 after 90 mins by liquid sc...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 238nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 251nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 268nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 369nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 614nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 728nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Centro De Investigaci£N Lilly S.A. Avda. De La Industria
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in hamster AV12 cell membranes co-expressing rat EAAT1 incubated for 90...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Eli Lilly
Curated by ChEMBL
Eli Lilly
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-Astemizole from human ERG by membrane binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GST-tagged IGF1R (957-1367) (unknown origin) expressed in baculovirus by time-resolved fluorescence assayMore data for this Ligand-Target Pair