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Found 524 with Last Name = 'stanton' and Initial = 'jl'
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036427(CHEMBL350265 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)
Affinity DataIC50:  0.100nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036401(CHEMBL163221 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.100nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18865(3-{3,5-dibromo-4-[4-hydroxy-3-(propan-2-yl)phenoxy...)
Affinity DataIC50:  0.110nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036399(Axitirome | CHEMBL159682 | N-(4-{3-[(4-Fluoro-phen...)
Affinity DataIC50:  0.140nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18862(2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]ac...)
Affinity DataIC50:  0.150nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036402(CHEMBL46882 | N-[3,5-dimethyl-4-(4'-hydroxy-3'-iso...)
Affinity DataIC50:  0.190nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036418(CHEMBL350049 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.230nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036423(CHEMBL164421 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.260nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036411(CHEMBL163324 | N-{3,5-Dichloro-4-[3-(4-chloro-benz...)
Affinity DataIC50:  0.270nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036410(CHEMBL159976 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataIC50:  0.310nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036424(CHEMBL159334 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.370nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  0.400nMAssay Description:In vitro inhibition of Human kideny reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036408(CHEMBL161828 | N-{4-[3-(4-Chloro-benzyl)-4-hydroxy...)
Affinity DataIC50:  0.430nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036417(CHEMBL423977 | N-{3,5-Dichloro-4-[3-(4-fluoro-benz...)
Affinity DataIC50:  0.680nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036404(CHEMBL159595 | N-(4-{3-[(4-Fluoro-phenyl)-hydroxy-...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036395(CHEMBL350199 | N-[4-(4-Hydroxy-3-isopropyl-phenoxy...)
Affinity DataIC50:  0.950nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036420(CHEMBL161535 | N-[4-(3-Isopropyl-4-methoxy-phenoxy...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of marmoset plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036406(CHEMBL163380 | [3,5-Dichloro-4-(4-hydroxy-3-isopro...)
Affinity DataIC50:  1.10nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036397(CHEMBL348983 | N-[3,5-Dichloro-4-(4-hydroxy-3-isop...)
Affinity DataIC50:  1.10nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036398(CHEMBL162692 | [3,5-Dibromo-4-(4-hydroxy-3-isoprop...)
Affinity DataIC50:  1.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036405(CHEMBL434476 | N-(3,5-Dichloro-4-{3-[(4-chloro-phe...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50034851(3-[(S)-3-Biphenyl-4-yl-2-(phosphonomethyl-amino)-p...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP 24.11) from rat kidney cortex membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021135(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021153(1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbo...)
Affinity DataIC50:  1.70nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021127(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021127(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021127(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  2nMAssay Description:Tested in vitro for the inhibition against neutral endopeptidase (NEP) from rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of Human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022586(5-[2-[2-Benzyl-3-(2-methyl-propane-2-sulfinyl)-pro...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:In vitro inhibition of porcine plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  2nMpH: 7.2Assay Description:In vitro inhibition of marmoset plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036426(CHEMBL159610 | N-{4-[3-(4-Fluoro-benzoyl)-4-hydrox...)
Affinity DataIC50:  2.5nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021790((S,S)1-(3-Mercapto-2-methyl-propionyl)-2,3-dihydro...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of dihydrofolate reductase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021783(1-(3-Mercapto-propionyl)-2,3-dihydro-1H-indole-2-c...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021184(1-(4-Benzyloxycarbonylamino-4-carboxy-butyryl)-oct...)
Affinity DataIC50:  2.70nMAssay Description:In vitro inhibition of angiotensin I converting enzyme from rabbit lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50021127(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021148(3-Benzylsulfanyl-2-(1-carboxymethyl-2-oxo-2,3,4,5-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50405179(CHEMBL2114418)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of Angiotensin I converting enzyme in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036415(CHEMBL163268 | N-[3,5-Dibromo-4-(4-hydroxy-3-isopr...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022582(CHEMBL53139 | Diastereomer-5-[2-[2-Benzyl-3-(2-met...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Rattus norvegicus)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50472804(CHEMBL83273)
Affinity DataIC50:  3.30nMAssay Description:Inhibitory activity tested against Pyruvate Dehydrogenase Kinase (PDHK) receptor from rats.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036414(CHEMBL346112 | N-{4-[3-(4-Chloro-benzoyl)-4-hydrox...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036430(CHEMBL347713 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataIC50:  3.5nMAssay Description:Ability to inhibit the bound [125I]L-T3 rat liver Nuclear L-triiodothyronine receptor is determined in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(RAT)
Ciba Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036422(CHEMBL163020 | N-[3,5-Difluoro-4-(4-hydroxy-3-isop...)
Affinity DataIC50:  3.60nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021151(6-tert-Butoxycarbonylamino-2-(1-carboxymethyl-2-ox...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022588(CHEMBL291787 | {2-[1-(4-Butylcarbamoyl-1-cyclohexy...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50022587(5-[2-(2-tert-Butylsulfanylmethyl-3-phenyl-propiony...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of purified Human kidney renin (250 pg/mL) incubated with angiotensinogen at pH 7.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50021138(2-(1-Carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-ben...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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