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Found 32 with Last Name = 'sugiyama' and Initial = 'm'
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50216728(CHEMBL359360)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50:  29nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50:  38nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50:  62nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50057477(4-(3-{3-[(4-Isobutyl-benzyl)-(4-isobutyl-phenyl)-a...)
Affinity DataIC50:  118nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069236(4-{2-[5-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50:  155nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069237(4-{2-[6-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50216727(CHEMBL422865)
Affinity DataIC50:  279nMAssay Description:In vitro inhibitory activity against rat testosterone 5 alpha reductase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069236(4-{2-[5-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 1 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069235(4-[2-(6-{[Bis-(4-fluoro-phenyl)-methyl]-carbamoyl}...)
Affinity DataIC50:  340nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069239(4-[2-(6-{[Bis-(4-methoxy-phenyl)-methyl]-carbamoyl...)
Affinity DataIC50:  930nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Homo sapiens (Human))
Sankyo

Curated by ChEMBL
LigandPNGBDBM50069236(4-{2-[5-(Benzhydryl-carbamoyl)-benzofuran-2-yl]-ph...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against human Steroid 5-alpha-reductase type 2 in COS-1 cells was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587449(CHEMBL5081145)
Affinity DataEC50:  8.90E+3nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50031414(1-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-...)
Affinity DataEC50:  3.00E+3nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587448(CHEMBL5087962)
Affinity DataEC50:  9.90E+4nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230986(Carperitide | SUN-4936)
Affinity DataEC50:  1nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230989(CHEMBL4092093)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230988(CHEMBL4089697)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230984(CHEMBL4099832)
Affinity DataEC50:  23nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Rattus norvegicus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230988(CHEMBL4089697)
Affinity DataEC50:  76nMAssay Description:Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230987(CHEMBL4071293)
Affinity DataEC50:  6.40E+4nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230986(Carperitide | SUN-4936)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230984(CHEMBL4099832)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230983(CHEMBL4061575)
Affinity DataEC50:  5.80nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230982(CHEMBL4097422)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM50587450(CHEMBL5088108)
Affinity DataEC50:  5.00E+4nMAssay Description:Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAtrial natriuretic peptide receptor 1(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50230981(CHEMBL4070239)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed