Affinity DataKi: 0.0320nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly
Curated by PDSP Ki Database
Eli Lilly
Curated by PDSP Ki Database
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Binding affinity imidazole glycerol phosphate dehydratase (IGPD) obtained from Cryptococcus neoformansMore data for this Ligand-Target Pair
Affinity DataKi: 0.690nMAssay Description:Displacement of [3H]CP-55940 from human cloned CB2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.860nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity to human wild type adenosine A2B receptor expressed in Expi293F cells assessed as inhibition constant by surface plasmon resonance a...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.15nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nM ΔG°: -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.40nM ΔG°: -54.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.5nM ΔG°: -54.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.60nM ΔG°: -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 1.60nM ΔG°: -54.4kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 1.89nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.99nMAssay Description:Displacement of [3H]paroxetine from 5HT reuptake siteMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2nM ΔG°: -53.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2.5nM ΔG°: -53.2kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2.70nM ΔG°: -53.0kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 2.76nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Binding affinity to CB2 receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2.90nM ΔG°: -52.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 2.90nM ΔG°: -52.8kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3nM ΔG°: -52.7kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 3.09nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Bristol-Myers Squibb Research And Development
Curated by ChEMBL
Affinity DataKi: 3.10nM ΔG°: -52.6kJ/moleT: 2°CAssay Description:To perform the competition binding assay, thawed membrane homogenate was
added to each well of a 96-well plate (20 ug/well). The experimental
compo...More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]succinamide from gamma secretase in THP1 cell membranesMore data for this Ligand-Target Pair