Compile Data Set for Download or QSAR
maximum 50k data
Found 506 with Last Name = 'toma' and Initial = 'l'
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176988(8-Chloro-1-(2,4-dichloro-phenyl)-1,3a,4,5,6,10b-he...)
Affinity DataKi:  0.000350nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176980(8-chloro-1-(2',4'-dichlorophenyl)-N-homopiperidin-...)
Affinity DataKi:  0.00100nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176989(8-chloro-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...)
Affinity DataKi:  0.00400nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176979(8-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.00520nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176986(8-bromo-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-...)
Affinity DataKi:  0.00800nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176990(8-chloro-1-(2',4'-dichlorophenyl)-N-p-methoxylphen...)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50216315((1R,4R)-2-(6-chloro-3-pyridinyl)-2,5-diazabicyclo[...)
Affinity DataKi:  0.0180nMAssay Description:Displacement of [3H]cytosine form alpha4beta2 nAChR in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50275878(3-(6-chloropyridin-3-yl)-3,6-diazabicyclo[3.1.1]he...)
Affinity DataKi:  0.0230nMAssay Description:Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50275880(3-(6-bromopyridin-3-yl)-3,6-diazabicyclo[3.1.1]hep...)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463758(CHEMBL4250302)
Affinity DataKi:  0.0560nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50275879(3-(pyridin-3-yl)-3,6-diazabicyclo[3.1.1]heptane | ...)
Affinity DataKi:  0.0560nMAssay Description:Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463741(CHEMBL4239232)
Affinity DataKi:  0.0570nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463759(CHEMBL4237636)
Affinity DataKi:  0.0630nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)
Affinity DataKi:  0.0750nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463736(CHEMBL4251203)
Affinity DataKi:  0.0970nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176987(8-methyl-1-(2',4'-dichlorophenyl)-N-pyrrolidin-1-y...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463756(CHEMBL4246561)
Affinity DataKi:  0.150nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50275932(3-(6-chloropyridazin-3-yl)-3,6-diazabicyclo[3.1.1]...)
Affinity DataKi:  0.168nMAssay Description:Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463750(CHEMBL4241807)
Affinity DataKi:  0.230nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463752(CHEMBL4247370)
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463743(CHEMBL4241370)
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463753(CHEMBL4250739)
Affinity DataKi:  0.270nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463754(CHEMBL4240635)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.280nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1B adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.290nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1D adrenergic receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463740(CHEMBL4251365)
Affinity DataKi:  0.290nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606735(CHEMBL5219718 | US11731973, Example 3)
Affinity DataKi:  0.300nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50176976(8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]CP55940 from CB1 receptor in CD1 mouse brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Università

Curated by ChEMBL
LigandPNGBDBM50176977(1,4-dihydroindeno[1,2-c]-pyrazole | 6-chloro-1-(2'...)
Affinity DataKi:  0.340nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463739(CHEMBL4237803)
Affinity DataKi:  0.340nMAssay Description:Inhibition of human recombinant HDAC1 using fluorogenic HDAC substrate after 15 mins by fluorimetrc methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463763(CHEMBL4248374)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606737(CHEMBL5218727 | US11731973, Example 5)
Affinity DataKi:  0.400nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Università

Curated by ChEMBL
LigandPNGBDBM50275933(3-(6-chloropyridin-3-yl)-6-methyl-3,6-diazabicyclo...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]epibatidine form alpha4beta2 nAChR in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(MOUSE)
Università

Curated by ChEMBL
LigandPNGBDBM50176979(8-methyl-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl...)
Affinity DataKi:  0.460nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataKi:  0.480nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463751(CHEMBL4244350)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606738(CHEMBL5218590 | US11731973, Example 6)
Affinity DataKi:  0.5nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463757(CHEMBL4249385)
Affinity DataKi:  0.510nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi:  0.540nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463764(CHEMBL4245007)
Affinity DataKi:  0.560nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463742(CHEMBL4242292)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606740(CHEMBL5220536 | US11731973, Example 30)
Affinity DataKi:  0.580nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  0.580nMAssay Description:The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1A adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606739(CHEMBL5220152 | US11731973, Example 7)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606742(CHEMBL5220948 | US11731973, Example 9)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM613740(3-(2-aminobenzoxazol-5-yl)-1-(2,2- dimethylbutyl)-...)
Affinity DataKi:  0.600nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(MOUSE)
Università

Curated by ChEMBL
LigandPNGBDBM50176976(8-chloro-1-(2',4'-dichlorophenyl)-N-cyclohexyl-1,4...)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]CP55940 from CB2 receptor in CD1 mouse spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Nestle Skin Health R&D

Curated by ChEMBL
LigandPNGBDBM50463767(CHEMBL4246919)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human recombinant HDAC1 using Fluor de Lys as substrate after 2 hrs by fluorescence methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50606736(CHEMBL5218916 | US11731973, Example 10)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM613743(1-(2,2-dimethylpropyl)-3-(2- ethylaminobenzoxazol-...)
Affinity DataKi:  0.800nMAssay Description:The model for screening the inhibitory activity of the molecules on mTOR was developed with the LANTHASCREEN™ technology (Lifetechnologies). The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 506 total ) | Next | Last >>
Jump to: