Affinity DataKi: 1.5nMAssay Description:Inhibition of human recombinant S-adenosyl-L-homocysteine hydrolase assessed as AdoHcy hydrolysis activity by Lineweaver-Burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of radiolabeled 4-(azetidin-1-yl)-3-[5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1-(tritritiomethyl)pyrazolo[3,4-d]pyrimidine from PD...More data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.40nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibitory concentration against human Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 48nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 151nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 269nMAssay Description:Binding affinity to muscarinic acetylcholine receptor M2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 275nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of human dUTPaseMore data for this Ligand-Target Pair
Affinity DataKi: 407nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Inhibitory concentration against human TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 871nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 871nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 912nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Reversible inhibition of rat liver S-adenosyl-L-homocysteine hydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.12E+3nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 1.38E+3nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.55E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 1.62E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+3nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.95E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 2.24E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 3.63E+3nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.08E+3nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
TargetSerine protease 1/Trypsin-2(Homo sapiens (Human))
Central Pharmaceutical Research Institute
Curated by ChEMBL
Central Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1.36E+4nMAssay Description:Inhibitory concentration against human TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.41E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 1.45E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical
Curated by ChEMBL
Taiho Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 1.80E+4nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: >2.09E+4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.19E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Mean inhibitory concentration against plasmin; n=3More data for this Ligand-Target Pair
Affinity DataKi: 2.30E+4nMAssay Description:Inhibitory concentration against human PlasminMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a expressed in tetracycline inducible HEK293 cells after 8 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >2.57E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair
Affinity DataKi: >2.75E+4nMAssay Description:Displacement of N-methyl [3H]-scopolamine from recombinant human muscarinic acetylcholine receptor M2 expressed in CHO cells after 2 hrs by liquid sc...More data for this Ligand-Target Pair