Compile Data Set for Download or QSAR
maximum 50k data
Found 38 with Last Name = 'vile' and Initial = 'j'
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102438(US8536158, B)
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102440(US8536158, D)
Affinity DataKi:  1nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102435(US8536158, 1)
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102436(US8536158, 2)
Affinity DataKi:  2nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102437(US8536158, 3)
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM50397646(CHEMBL2181804 | US8536158, A)
Affinity DataKi:  7nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102441(US8536158, E)
Affinity DataKi:  258nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Atopix Therapeutics

US Patent
LigandPNGBDBM102439(US8536158, C)
Affinity DataKi:  979nMAssay Description:Radioligand binding assay using CRTH2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165496(1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50:  3.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165488(1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50:  4.10nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165497(3-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165486(1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165498(1-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50:  6.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165492(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50:  9.5nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165479(1-[2-Fluoro-5-(4-oxo-3,4-dihydro-phthalazin-1-ylme...)
Affinity DataIC50:  9.80nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165499(1-(4-Methoxy-phenyl)-3-methyl-1H-pyrazole-4-carbox...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165478(1-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phe...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165487(1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165485(2,2,2-Trifluoro-N-[3-(4-oxo-3,4-dihydro-phthalazin...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165472(1-(2-chloro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)m...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165477(CHEMBL371425 | N-(3-((4-oxo-3,4-dihydrophthalazin-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165480(4-Methyl-2-phenyl-thiazole-5-carboxylic acid [3-(4...)
Affinity DataIC50:  27nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165484(1-(2-methoxy-5-((4-oxo-3,4-dihydrophthalazin-1-yl)...)
Affinity DataIC50:  33nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165474(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)phenyl...)
Affinity DataIC50:  36nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165495(CHEMBL193903 | N-[3-(4-Oxo-3,4-dihydro-phthalazin-...)
Affinity DataIC50:  47nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165483(CHEMBL381208 | N-Ethyl-3-(4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165471(CHEMBL196507 | Cyclopropanecarboxylic acid [3-(4-o...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50240980(CHEMBL372450 | N-(3-((4-oxo-3,4-dihydrophthalazin-...)
Affinity DataIC50:  56nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165481(CHEMBL425560 | N-(3-((4-oxo-3,4-dihydrophthalazin-...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165494(CHEMBL381652 | N-(3-((4-oxo-3,4-dihydrophthalazin-...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165493(CHEMBL193638 | [3-(4-Oxo-3,4-dihydro-phthalazin-1-...)
Affinity DataIC50:  116nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165489(4-(3-(2-oxopyrrolidin-1-yl)benzyl)phthalazin-1(2H)...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165482(2-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50:  180nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165490(4-[3-(3-Methyl-[1,2,4]oxadiazol-5-yl)-benzyl]-2H-p...)
Affinity DataIC50:  189nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165491(CHEMBL193917 | Ethanesulfonic acid [3-(4-oxo-3,4-d...)
Affinity DataIC50:  290nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165473(CHEMBL193512 | N-[3-(4-Oxo-3,4-dihydro-phthalazin-...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM50165475(1-[3-(4-Oxo-3,4-dihydro-phthalazin-1-ylmethyl)-phe...)
Affinity DataIC50:  540nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Kudos Horsham

Curated by ChEMBL
LigandPNGBDBM27660(4-Benzyl-2H-phthalazin-1-one | 4-benzyl-1,2-dihydr...)
Affinity DataIC50:  770nMAssay Description:Inhibitory concentration against human poly (ADP-ribose) polymerase 1 (PARP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed