TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataKi: 279nMAssay Description:Inhibition of AChE in rat cortex using acetylthiocholine iodide as substrate by double Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 430nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+4nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataKi: 2.07E+5nMAssay Description:Inhibition of Carboxypeptidase A assessed as amount of Cl-CPL consumed by UV spectrometerMore data for this Ligand-Target Pair
Affinity DataIC50: 2.89nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 3.38nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 3.42nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 4.98nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 8.42nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.98nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using PI(3,4)P2 as substrate after 3 hrs incubation by competitive fluorescence polarization kin...More data for this Ligand-Target Pair
Affinity DataIC50: 16.5nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of autophosphorylation of recombinant his-tagged EGFR (amino acid 645-1186) (unknown origin) expressed in Sf-9 cells after 10 mins by time...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21.8nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant PI3Kalpha (unknown origin) using PI(3,4)P2 as substrate after 3 hrs incubation by competitive fluorescence polarization kin...More data for this Ligand-Target Pair
Affinity DataIC50: 32.6nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 34.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
School Of Traditional Chinese Pharmacy
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using diC8-PI(4,5)P2 as substrate incubated for 3 hrs in presence of ATP by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 47.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 47.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 49.8nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 52.2nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 54.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 54.4nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 55.7nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of C-terminal His-tagged microtubule-stimulated KSP motor domain (1 to 369) ATPase activity (unknown origin) preincubated for 30 mins foll...More data for this Ligand-Target Pair
Affinity DataIC50: 59.3nMpH: 7.2 T: 2°CAssay Description:VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...More data for this Ligand-Target Pair