Compile Data Set for Download or QSAR
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Found 474 with Last Name = 'wen' and Initial = 'q'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546397(CHEMBL4776352)
Affinity DataIC50:  0.0770nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50546402(CHEMBL4762995)
Affinity DataIC50:  0.0980nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640879(US20230399327, Example 93)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640886(US20230399327, Example 100)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640887(US20230399327, Example 101)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640888(US20230399327, Example 102)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640890(US20230399327, Example 104)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640891(US20230399327, Example 105)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640893(US20230399327, Example 107)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640894(US20230399327, Example 108)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640895(US20230399327, Example 109)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640896(US20230399327, Example 110)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640897(US20230399327, Example 111)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640898((R)-2-((2-((6-methoxy-2-methyl-1,2,3,4 tetrahydroi...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50528415(CHEMBL4457064)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of Akt3 (unknown origin) by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640799(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640800(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640801(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640802(8-(2-fluorophenyl)-N-(2-methoxy-6-methyl-5,6,7,8-t...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640803(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640804(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640811(3-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-n...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640815(1-(4-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640816(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640817(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640818(8-(2-fluoro-6-methoxyphenyl)-N-(2-methoxy-6-methyl...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640820(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640821(1-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-n...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640833(N8-isobutyl-N2-(2-methoxy-6-methyl-5,6,7,8-tetrahy...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640834(8-(6-chloropyridin-2-yl)-N-(2-methoxy-6-methyl-5,6...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640835(N2-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-naph...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640836((S)?N8-(3,3-dimethylbut-2-yl)-N2-(2-methoxy-6-meth...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640838(N-(2-ethoxy-6-methyl-5,6,7,8-tetrahydro-1,6-naphth...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640839(8-(2-methoxyphenyl)-N-(6-methyl-5,6,7,8-tetrahydro...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640844(N2-(2-ethoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640845(8-(1,5-dimethyl-1H-pyrazol-4-yl)-N-(2-methoxy-6-me...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640849((R)?N8-(3,3-dimethylbut-2-yl)-N2-(2-ethoxy-6-methy...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640850(8-benzyl-N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640851(3-((8-(1,5-dimethyl-1H-pyrazol-4-yl)quinazolin-2-y...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640854(6-methyl-3-((8-(neopentylamino)pyrido[3,4-d]pyrimi...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640863(3-((8-(cyclohex-1-en-1-yl)pyrido[3,4-d]pyrimidin-2...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640864((R)-6-methyl-3-((8-(2-methylpiperidin-1-yl)pyrido[...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640865(6-methyl-3-((8-(((1-methylcyclopropyl)methyl)amino...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640866(3-((8-(4,4-difluoropiperidin-1-yl)piperido[3,4-d]p...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640869(3-((8-(4,4-difluoropiperidin-1-yl)pyrido[3,4-d]pyr...)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640875(US20230399327, Example 89)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Adlai Nortye Biopharma Co.

US Patent
LigandPNGBDBM640876(US20230399327, Example 90)
Affinity DataIC50: <0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50528409(CHEMBL4441825)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of Akt3 (unknown origin) by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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