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Found 44 with Last Name = 'wilkinson' and Initial = 'tj'
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249413(5-amino-4-(bicyclo[2.2.1]heptan-2-ylamino)-6-morph...)
Affinity DataIC50:  2nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  6nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249448(4-(4-acetylpiperazin-1-yl)-5-amino-6-(isobutylamin...)
Affinity DataIC50:  9nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249380(5-amino-4-(cyclopentylamino)-6-morpholinopyrimidin...)
Affinity DataIC50:  13nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249449(5-Amino-4-(1,1-dioxo-tetrahydro-1lambda*6*-thiophe...)
Affinity DataIC50:  14nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50:  18nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249445(5-amino-4-morpholino-6-(piperidin-1-yl)pyrimidine-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249381(5-amino-4-(cyclohexylamino)-6-morpholinopyrimidine...)
Affinity DataIC50:  23nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249447(5-amino-4-(isobutylamino)-6-(2-methoxyethylamino)p...)
Affinity DataIC50:  24nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249450(5-amino-4-(3-hydroxyazetidin-1-yl)-6-(isobutylamin...)
Affinity DataIC50:  32nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249415(5-amino-4-morpholino-6-(pyrrolidin-1-yl)pyrimidine...)
Affinity DataIC50:  60nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249451(4-((1H-tetrazol-5-yl)methylamino)-5-amino-6-(isobu...)
Affinity DataIC50:  62nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249378(5-amino-4-morpholino-6-(phenylamino)pyrimidine-2-c...)
Affinity DataIC50:  110nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249412(5-amino-4-(sec-butylamino)-6-morpholinopyrimidine-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249414(5-amino-4-morpholino-6-(tetrahydrofuran-3-ylamino)...)
Affinity DataIC50:  340nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249379(5-amino-4-(isopropylamino)-6-morpholinopyrimidine-...)
Affinity DataIC50:  560nMAssay Description:Inhibition of cathepsin K (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50:  560nMAssay Description:Inhibition of cathepsin S (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  890nMAssay Description:Inhibition of cathepsin S (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50:  910nMAssay Description:Inhibition of cathepsin S (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of cathepsin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of cathepsin L (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249446(5-amino-4-(isobutylamino)-6-(piperazin-1-yl)pyrimi...)
Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249411(5-amino-4-morpholino-6-(neopentylamino)pyrimidine-...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50249410(5-amino-4-(isobutylamino)-6-morpholinopyrimidine-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed