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Found 548 with Last Name = 'wright' and Initial = 'jl'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.5nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  0.520nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.690nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.86nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289457((R)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-...)
Affinity DataKi:  2nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  2.20nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-NPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048302(4-[(R)-5-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmeth...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289448(1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-2-ol...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080809(7-(4-Phenyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-chr...)
Affinity DataKi:  4.40nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048301(4-[1-((R)-3-Phenyl-cyclohex-3-enylmethyl)-1,2,3,6-...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080797(7-[(2-Phenylamino-ethylamino)-methyl]-chromen-2-on...)
Affinity DataKi:  5.80nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080796(7-[4-(3-Chloro-4-methyl-phenyl)-piperazin-1-ylmeth...)
Affinity DataKi:  6.90nMAssay Description:Binding affinity using [3H]spiperone displacement from cloned human Dopamine receptor D4.2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  7.80nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071960(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  8nMAssay Description:Compound was evaluated for stimulation of mitogenesis in Dopamine receptor D3 transfected CHO p-5 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-N-0437More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080794(7-[(2-p-Tolylamino-ethylamino)-methyl]-chromen-2-o...)
Affinity DataKi:  10nMAssay Description:Binding affinity using [3H]spiperone displacement from cloned human Dopamine receptor D4.2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048300(4-(1-[methyl cyclohex-3-en-3-yl phenol]-1,2,3,6-te...)
Affinity DataKi:  10.3nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080787(6-(4-p-Tolyl-piperazin-1-ylmethyl)-chromen-2-one |...)
Affinity DataKi:  11nMAssay Description:Binding affinity using [3H]spiperone displacement from cloned human Dopamine receptor D4.2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289452((S)-1-Phenoxy-3-(4-phenoxy-piperidin-1-yl)-propan-...)
Affinity DataKi:  12nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080810(7-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-c...)
Affinity DataKi:  14nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080798(7-{[2-(4-Chloro-phenylamino)-ethylamino]-methyl}-c...)
Affinity DataKi:  14nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080800(7-{[2-(3-Chloro-4-methyl-phenylamino)-ethylamino]-...)
Affinity DataKi:  16nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080788(7-(4-o-Tolyl-piperazin-1-ylmethyl)-chromen-2-one |...)
Affinity DataKi:  16nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  16.6nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D3 evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGalanin receptor type 3(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50187923(1,3-dihydro-1-phenyl-3-[[3-(trilfluoromethyl)pheny...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]galanin from human GAL3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080790(7-(4-p-Tolyl-piperazin-1-ylmethyl)-chromen-2-one |...)
Affinity DataKi:  17nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289451(1-(Naphthalen-1-yloxy)-3-(4-phenoxy-piperidin-1-yl...)
Affinity DataKi:  18nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289460(1-(4-Benzyl-piperidin-1-yl)-3-(4-chloro-phenoxy)-p...)
Affinity DataKi:  18nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080786(7-(4-Phenyl-piperidin-1-ylmethyl)-chromen-2-one | ...)
Affinity DataKi:  19nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080806(7-{[2-(3,4-Dimethyl-phenylamino)-ethylamino]-methy...)
Affinity DataKi:  21nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50287161(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid [2...)
Affinity DataKi:  24nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50287178(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  24nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  25.5nMAssay Description:Binding affinity of the compound towards human Dopamine receptor D2L evaluated using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,...)
Affinity DataKi:  26nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289447(1-(4-Benzyl-piperidin-1-yl)-3-(naphthalen-1-yloxy)...)
Affinity DataKi:  26nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080808(7-(4-Phenyl-piperazin-1-ylmethyl)-chromen-2-one | ...)
Affinity DataKi:  27nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)
Affinity DataKi:  28nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080801(6-(4-Phenyl-piperazin-1-ylmethyl)-chromen-2-one | ...)
Affinity DataKi:  30nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080805(7-[(3-Phenylamino-propylamino)-methyl]-chromen-2-o...)
Affinity DataKi:  31nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289456(1-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-3-(naphthal...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289450(1-(Naphthalen-1-yloxy)-3-(4-phenylsulfanyl-piperid...)
Affinity DataKi:  32nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50080795(7-(4-m-Tolyl-piperazin-1-ylmethyl)-chromen-2-one |...)
Affinity DataKi:  32nMAssay Description:Compound was tested for the inhibition of [3H]thymidine uptake in CHO p-5 cells transfected with human Dopamine receptor D4.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289463(1-(4-Benzyl-piperidin-1-yl)-3-phenoxy-propan-2-ol ...)
Affinity DataKi:  34nMAssay Description:Binding affinity against human cloned D4 receptor transfected in CHO-K1 cells by [3H]- spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50287176(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  39nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails Article
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