Compile Data Set for Download or QSAR
maximum 50k data
Found 45 with Last Name = 'xiao' and Initial = 'wl'
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.860nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of ZAP70 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of SRC (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of PKCdelta (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of ALK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465346(CHEMBL4286991)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of BRAF (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PDK1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465342(CHEMBL4293812)
Affinity DataIC50:  11nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FAK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  12nMAssay Description:Inhibition of AKT1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein ENL(Homo sapiens)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50529556(CHEMBL4552313)
Affinity DataIC50:  18nMAssay Description:Inhibition of His6-tagged ENL YEATS domain (unknown origin) expressed in Escherichia coli BL21 DE3 and biotinylated H3K27ac peptide interaction using...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465348(CHEMBL4292650)
Affinity DataIC50:  22nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50:  23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)
Affinity DataIC50:  23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of GSK3b (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50:  28nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465345(18-Oxoferruginol | acs.jmedchem.1c00409_ST.768)
Affinity DataIC50:  34nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465347(CHEBI:52486 | POMIFERIN A)
Affinity DataIC50:  46nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465338(15-Hydroxydehydroabietic Acid | CHEMBL598566)
Affinity DataIC50:  49nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  58nMAssay Description:Inhibition of PIM1 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465343(CHEMBL4279751)
Affinity DataIC50:  85nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465338(15-Hydroxydehydroabietic Acid | CHEMBL598566)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465339(CHEMBL4285076)
Affinity DataIC50: >100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465339(CHEMBL4285076)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465348(CHEMBL4292650)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465344(CHEMBL4294902)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465340(CHEMBL4278579)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465346(CHEMBL4286991)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465341(CHEMBL4289234)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50143600(CHEBI:29571 | Dehydroabietic Acid)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465342(CHEMBL4293812)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465344(CHEMBL4294902)
Affinity DataIC50: >100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465341(CHEMBL4289234)
Affinity DataIC50: >100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465340(CHEMBL4278579)
Affinity DataIC50: >100nMAssay Description:Inhibition of SYK (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465343(CHEMBL4279751)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50465345(18-Oxoferruginol | acs.jmedchem.1c00409_ST.768)
Affinity DataIC50: >100nMAssay Description:Inhibition of JAK3 (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50595789(CHEMBL5200746)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in LDH release pretreated for 0.5 hrs f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
Yunnan Research & Development Center For Natural Products

Curated by ChEMBL
LigandPNGBDBM50595789(CHEMBL5200746)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS/nigericin-treated mouse J774A.1 cells assessed as decrease in IL-1beta level pretreated for 0.5 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein ENL(Homo sapiens)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50596391(CHEMBL5171384)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of His6-tagged ENL YEATS domain (unknown origin) expressed in Escherichia coli BL21 DE3 and biotinylated H3K27ac peptide interaction using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50593608(CHEMBL5196901)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50593607(CHEMBL5186663)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50593606(CHEMBL5189793)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of SARS-CoV-2 MPro incubated for 5 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein ENL(Homo sapiens)
Yunnan University

Curated by ChEMBL
LigandPNGBDBM50596391(CHEMBL5171384)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to His6-tagged ENL YEATS domain (unknown origin) expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by surface...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed