BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50216347((1R,4R)-2-(3-pyridinyl)-2,5-diazabicyclo[2.2.1]hep...)

Ki: 0.300nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210335(CHEMBL3898434)

Ki: 0.300nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210334(CHEMBL3948977)

Ki: 0.300nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532486(CHEMBL4564992)

Ki: 0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532486(CHEMBL4564992)

Ki: 0.300nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50166908(5,8,14-triazatetracyclo[10.3.1.02,11.04,9]hexadeca...)

Ki: 0.400nMAssay Description:Binding affinity to alpha4beta2 nAChRMore data for this Ligand-Target Pair

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3D Structure (crystal)

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532508(CHEMBL4471576)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532518(CHEMBL4440420)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532506(CHEMBL4536431)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210335(CHEMBL3898434)

Ki: 0.5nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532508(CHEMBL4471576)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532518(CHEMBL4440420)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532506(CHEMBL4536431)

Ki: 0.5nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532502(CHEMBL4538923)

Ki: 0.700nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532502(CHEMBL4538923)

Ki: 0.700nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210334(CHEMBL3948977)

Ki: 0.700nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532512(CHEMBL4539105)

Ki: 0.800nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210337(CHEMBL3970672)

Ki: 0.800nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210337(CHEMBL3970672)

Ki: 0.800nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532512(CHEMBL4539105)

Ki: 0.800nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532507(CHEMBL4593797)

Ki: 0.900nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532507(CHEMBL4593797)

Ki: 0.900nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50216347((1R,4R)-2-(3-pyridinyl)-2,5-diazabicyclo[2.2.1]hep...)

Ki: 1nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532489(CHEMBL4434692)

Ki: 1.10nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50088438(1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1...)

Ki: 1.10nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

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Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532489(CHEMBL4434692)

Ki: 1.10nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532503(CHEMBL4458060)

Ki: 1.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532521(CHEMBL4524740)

Ki: 1.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532521(CHEMBL4524740)

Ki: 1.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532503(CHEMBL4458060)

Ki: 1.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532505(CHEMBL4535404)

Ki: 1.80nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532505(CHEMBL4535404)

Ki: 1.80nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50400743(CHEMBL2203549)

Ki: 2.10nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL

BDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)

Ki: 2.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells measured after 30 minsMore data for this Ligand-Target Pair

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Details Article PubMed DrugBank

Sodium-dependent noradrenaline transporter(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL

BDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)

Ki: 2.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells measured after 30 minsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532516(CHEMBL4460187)

Ki: 2.60nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532516(CHEMBL4460187)

Ki: 2.60nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532493(CHEMBL4533250)

Ki: 2.70nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532493(CHEMBL4533250)

Ki: 2.70nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50216347((1R,4R)-2-(3-pyridinyl)-2,5-diazabicyclo[2.2.1]hep...)

Ki: 3.10nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50210338(CHEMBL3926480)

Ki: 3.10nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)

Ki: 3.10nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532515(CHEMBL4470605)

Ki: 3.20nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532515(CHEMBL4470605)

Ki: 3.20nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532513(CHEMBL4579980)

Ki: 3.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532513(CHEMBL4579980)

Ki: 3.40nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL

BDBM50088438(1-(pyridin-3-yl)-1,4-diazepane | 1-Pyridin-3-yl-[1...)

Ki: 3.40nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair

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PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

BDBM50064957(CHEMBL76806 | N-(1-Benzyl-piperidin-4-yl)-2-(2-flu...)

Ki: 3.60nMAssay Description:Binding affinity to sigma 1 receptorMore data for this Ligand-Target Pair

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Sigma non-opioid intracellular receptor 1(RAT)
East China Normal University

Curated by ChEMBL

BDBM50532501(CHEMBL4452090)

Ki: 3.70nMAssay Description:Displacement of [3H]-pentazocine from rat brain sigma1 receptor by PDSP assayMore data for this Ligand-Target Pair