Compile Data Set for Download or QSAR
maximum 50k data
Found 326 with Last Name = 'zimmerli' and Initial = 'd'
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188855(1-phenyl-8-(1-phenyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188855(1-phenyl-8-(1-phenyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataIC50:  15nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175903(1-Phenyl-8-((cis,1S,2S)-2-phenyl-cyclohexyl)-1,3,8...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188374(1-phenyl-8-(2-phenyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataIC50:  150nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50265098(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)ben...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322424(3-Fluoro-4-[4-(2-isobutoxy-5-methanesulfonyl-benzo...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188806((S)-4-(4-fluoro-phenyl)-8-[(1R,2R)-2-(4-fluoro-phe...)
Affinity DataIC50:  1.09E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322428(CHEMBL1171498 | rac-4-{4-[5-Methanesulfonyl-2-(2,2...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188849(4-(4-fluoro-phenyl)-8-[1-(4-fluoro-phenyl)-cyclohe...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188803((S)-4-phenyl-8-((1R,2R)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188813((S)-4-(4-fluoro-phenyl)-8-[(1S,2S)-2-(4-fluoro-phe...)
Affinity DataIC50:  1.55E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188364(8-[2-(4-fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phe...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of hERG potassium channel expressed in CHO cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322426(3-Fluoro-4-{4-[5-methanesulfonyl-2-(2,2,2-trifluor...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188376(8-(2-hydroxy-2-phenyl-cyclohexyl)-1-phenyl-1,3,8-t...)
Affinity DataIC50:  2.70E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4...)
Affinity DataIC50:  2.73E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4...)
Affinity DataIC50:  2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188843(8-(1-phenyl-cyclohexyl)-4-propyl-2,8-diaza-spiro[4...)
Affinity DataIC50:  2.76E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322427(CHEMBL1172999 | rac-Fluoro-4-{4-[5-methanesulfonyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188879(CHEMBL214057 | rac-8-[1-(4-fluoro-phenyl)-cyclohex...)
Affinity DataIC50:  3.03E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322425(3-Fluoro-4-[4-(2-isopropoxy-5-methanesulfonyl-benz...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188810((R)-4-phenyl-8-((1S,2S)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  3.49E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188859(CHEMBL378665 | rac-4-(4-fluoro-phenyl)-8-(1-o-toly...)
Affinity DataIC50:  3.85E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188803((S)-4-phenyl-8-((1R,2R)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  3.92E+3nMAssay Description:Displacement of [3H]naloxone from human mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188361(4-phenyl-8-(2-phenyl-cyclohexyl)-2,8-diaza-spiro[4...)
Affinity DataIC50:  3.92E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188805((R)-4-phenyl-8-((1R,2R)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  5.48E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188374(1-phenyl-8-(2-phenyl-cyclohexyl)-1,3,8-triaza-spir...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50175903(1-Phenyl-8-((cis,1S,2S)-2-phenyl-cyclohexyl)-1,3,8...)
Affinity DataIC50:  6.00E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188844(4-phenyl-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4...)
Affinity DataIC50:  6.15E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188844(4-phenyl-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4...)
Affinity DataIC50:  6.15E+3nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188804((R)-4-(4-fluoro-phenyl)-8-[(1R,2R)-2-(4-fluoro-phe...)
Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322430(CHEMBL1172199 | rac-[4-(2-Fluoro-4-trifluoromethyl...)
Affinity DataIC50:  6.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188863(CHEMBL436752 | rac-4-(4-fluoro-phenyl)-8-[1-(3-flu...)
Affinity DataIC50:  7.18E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188844(4-phenyl-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4...)
Affinity DataIC50:  7.64E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188844(4-phenyl-8-(1-phenyl-cyclohexyl)-2,8-diaza-spiro[4...)
Affinity DataIC50:  7.64E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188849(4-(4-fluoro-phenyl)-8-[1-(4-fluoro-phenyl)-cyclohe...)
Affinity DataIC50:  7.80E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188845(4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  7.83E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188845(4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-d...)
Affinity DataIC50:  7.83E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188857(8-[1-(3-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Affinity DataIC50:  8.04E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188857(8-[1-(3-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Affinity DataIC50:  8.04E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188861(4-phenyl-8-(1-p-tolyl-cyclohexyl)-2,8-diaza-spiro[...)
Affinity DataIC50:  9.12E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188861(4-phenyl-8-(1-p-tolyl-cyclohexyl)-2,8-diaza-spiro[...)
Affinity DataIC50:  9.12E+3nMAssay Description:Displacement of [3H]naloxone from mu opioid receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188861(4-phenyl-8-(1-p-tolyl-cyclohexyl)-2,8-diaza-spiro[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322429(CHEMBL1171499 | rac-[5-Methanesulfonyl-2-(2,2,2-tr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50322435(CHEMBL1169701 | rac-[4-(3-Chloro-5-trifluoromethyl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188803((S)-4-phenyl-8-((1R,2R)-2-phenyl-cyclohexyl)-2,8-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188364(8-[2-(4-fluoro-phenyl)-2-hydroxy-cyclohexyl]-4-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188856(8-[1-(4-chloro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188845(4-(4-fluoro-phenyl)-8-(1-m-tolyl-cyclohexyl)-2,8-d...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188857(8-[1-(3-fluoro-phenyl)-cyclohexyl]-4-phenyl-2,8-di...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188861(4-phenyl-8-(1-p-tolyl-cyclohexyl)-2,8-diaza-spiro[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]NOP from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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