BindingDB logo
myBDB logout

11 similar compounds to monomer 50428400

Compile data set for download or QSAR
Wt: 368.4
BDBM10899
Purchase
Wt: 297.3
BDBM45795
Purchase
Wt: 275.3
BDBM46877
Purchase
Wt: 290.3
BDBM50465
Purchase
Wt: 622.7
BDBM91709
Wt: 233.2
BDBM50078825
Purchase
Wt: 276.3
BDBM50193473
Wt: 436.9
BDBM50268206
Purchase
Wt: 401.6
BDBM50338963
Wt: 275.3
BDBM50394322
Wt: 263.3
BDBM50027958
Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 10899,45795,46877,50465,91709,50078825,50193473,50268206,50338963,50394322,50027958   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (human))
BDBM50193473
PNG
(CHEMBL434365 | N-(4-(2-aminoethyl)phenyl)benzenesu...)
Show SMILES NCCc1ccc(NS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C14H16N2O2S/c15-11-10-12-6-8-13(9-7-12)16-19(17,18)14-4-2-1-3-5-14/h1-9,16H,10-11,15H2
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assay


J Med Chem 49: 5217-25 (2006)


Article DOI: 10.1021/jm060469q
BindingDB Entry DOI: 10.7270/Q2416WQN
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (human))
BDBM91709
PNG
(Sulfonamide, 11)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
59n/an/an/an/an/an/an/an/a



Egyptian Petroleum Research Institute



Assay Description
Inhibition assay using carbonic anhydrases.


J Enzyme Inhib Med Chem 24: 499-505 (2009)


Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC
More data for this
Ligand-Target Pair
Carbonic Anhydrase (hpCA)


(Helicobacter pylori J99)
BDBM10899
PNG
(1-N-(4-tert-butylbenzene)benzene-1,4-disulfonamide...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C16H20N2O4S2/c1-16(2,3)12-4-8-15(9-5-12)24(21,22)18-13-6-10-14(11-7-13)23(17,19)20/h4-11,18H,1-3H3,(H2,17,19,20)
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
60n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2117-26 (2006)


Article DOI: 10.1021/jm0512600
BindingDB Entry DOI: 10.7270/Q2ZS2TQB
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM91709
PNG
(Sulfonamide, 11)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
64n/an/an/an/an/an/an/an/a



Egyptian Petroleum Research Institute



Assay Description
Inhibition assay using carbonic anhydrases.


J Enzyme Inhib Med Chem 24: 499-505 (2009)


Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM10899
PNG
(1-N-(4-tert-butylbenzene)benzene-1,4-disulfonamide...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C16H20N2O4S2/c1-16(2,3)12-4-8-15(9-5-12)24(21,22)18-13-6-10-14(11-7-13)23(17,19)20/h4-11,18H,1-3H3,(H2,17,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
119n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2117-26 (2006)


Article DOI: 10.1021/jm0512600
BindingDB Entry DOI: 10.7270/Q2ZS2TQB
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Carbonic anhydrase 12


(Homo sapiens (human))
BDBM91709
PNG
(Sulfonamide, 11)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
145n/an/an/an/an/an/an/an/a



Egyptian Petroleum Research Institute



Assay Description
Inhibition assay using carbonic anhydrases.


J Enzyme Inhib Med Chem 24: 499-505 (2009)


Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (human))
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
181 -9.19n/an/an/an/an/a7.525



Ataturk University



Assay Description
An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...


J Enzyme Inhib Med Chem 28: 294-8 (2013)


Article DOI: 10.3109/14756366.2012.658788
BindingDB Entry DOI: 10.7270/Q2TH8KKX
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
485 -8.61n/an/an/an/an/a7.525



Ataturk University



Assay Description
An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...


J Enzyme Inhib Med Chem 28: 294-8 (2013)


Article DOI: 10.3109/14756366.2012.658788
BindingDB Entry DOI: 10.7270/Q2TH8KKX
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (human))
BDBM91709
PNG
(Sulfonamide, 11)
Show SMILES NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)S(=O)(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
Show InChI InChI=1S/C24H22N4O8S4/c25-37(29,30)21-13-5-19(6-14-21)27-39(33,34)23-9-1-17(2-10-23)18-3-11-24(12-4-18)40(35,36)28-20-7-15-22(16-8-20)38(26,31)32/h1-16,27-28H,(H2,25,29,30)(H2,26,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
675n/an/an/an/an/an/an/an/a



Egyptian Petroleum Research Institute



Assay Description
Inhibition assay using carbonic anhydrases.


J Enzyme Inhib Med Chem 24: 499-505 (2009)


Article DOI: 10.1080/14756360802218441
BindingDB Entry DOI: 10.7270/Q24748GC
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (human))
BDBM10899
PNG
(1-N-(4-tert-butylbenzene)benzene-1,4-disulfonamide...)
Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O
Show InChI InChI=1S/C16H20N2O4S2/c1-16(2,3)12-4-8-15(9-5-12)24(21,22)18-13-6-10-14(11-7-13)23(17,19)20/h4-11,18H,1-3H3,(H2,17,19,20)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
1.30E+4n/an/an/an/an/an/an/an/a



Kochi Medical School



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


J Med Chem 49: 2117-26 (2006)


Article DOI: 10.1021/jm0512600
BindingDB Entry DOI: 10.7270/Q2ZS2TQB
More data for this
Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase


(Mus musculus)
BDBM50338963
PNG
(CHEMBL1685062 | para-Dodecyl-N-phenylbenzenesulfon...)
Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C24H35NO2S/c1-2-3-4-5-6-7-8-9-10-12-15-22-18-20-24(21-19-22)28(26,27)25-23-16-13-11-14-17-23/h11,13-14,16-21,25H,2-10,12,15H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



The University of Arizona

Curated by ChEMBL


Assay Description
Displacement of biotinylated phosphatidylinositol-3,4,5-phosphate from mouse AKT1 PH domain by surface plasmon resonance competitive binding assay


Bioorg Med Chem 19: 2046-54 (2011)


Article DOI: 10.1016/j.bmc.2011.01.049
BindingDB Entry DOI: 10.7270/Q2TQ61TR
More data for this
Ligand-Target Pair
Transmembrane protease serine 6


(Homo sapiens)
BDBM50394322
PNG
(CHEMBL2159365)
Show SMILES NC(=N)c1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C13H13N3O2S/c14-13(15)10-6-8-12(9-7-10)19(17,18)16-11-4-2-1-3-5-11/h1-9,16H,(H3,14,15)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
8.80E+4n/an/an/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...


Bioorg Med Chem 20: 6489-505 (2012)


Article DOI: 10.1016/j.bmc.2012.08.042
BindingDB Entry DOI: 10.7270/Q2SB46VD
More data for this
Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT)


(Homo sapiens (Human))
BDBM50268206
PNG
(4-chloro-N-(4-(4-methylphenylsulfonamido)phenyl)be...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C19H17ClN2O4S2/c1-14-2-10-18(11-3-14)27(23,24)21-16-6-8-17(9-7-16)22-28(25,26)19-12-4-15(20)5-13-19/h2-13,21-22H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



St. Jude Children's Research Hospital

Curated by ChEMBL


Assay Description
Inhibition of human liver CE1-mediated O-nitrophenyl acetate hydrolysis by spectrophotometry


J Med Chem 52: 3742-52 (2009)


Article DOI: 10.1021/jm9001296
BindingDB Entry DOI: 10.7270/Q28916SC
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50394322
PNG
(CHEMBL2159365)
Show SMILES NC(=N)c1ccc(cc1)S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C13H13N3O2S/c14-13(15)10-6-8-12(9-7-10)19(17,18)16-11-4-2-1-3-5-11/h1-9,16H,(H3,14,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Bonn

Curated by ChEMBL


Assay Description
Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry


Bioorg Med Chem 20: 6489-505 (2012)


Article DOI: 10.1016/j.bmc.2012.08.042
BindingDB Entry DOI: 10.7270/Q2SB46VD
More data for this
Ligand-Target Pair
Cytochrome b-c1 complex subunit 7


(Homo sapiens)
BDBM50027958
PNG
(CHEMBL3360255)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc(O)cc1
Show InChI InChI=1S/C13H13NO3S/c1-10-2-8-13(9-3-10)18(16,17)14-11-4-6-12(15)7-5-11/h2-9,14-15H,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



Yonsei University

Curated by ChEMBL


Assay Description
Modulation of UQCRB in human HepG2 cells assessed as inhibition of HIF-1alpha for 4 hrs under 1%O2 by Western blot analysis


J Med Chem 57: 7990-8 (2014)


Article DOI: 10.1021/jm500863j
BindingDB Entry DOI: 10.7270/Q24Q7WK4
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase mTOR


(Homo sapiens (human))
BDBM50078825
PNG
(CHEMBL83148 | N-Phenyl-benzenesulfonamide | phenyl...)
Show SMILES O=S(=O)(Nc1ccccc1)c1ccccc1
Show InChI InChI=1S/C12H11NO2S/c14-16(15,12-9-5-2-6-10-12)13-11-7-3-1-4-8-11/h1-10,13H
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/a 1.00E+6n/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Dissociation constant when binding to FK506 binding protein (FKBP).


J Med Chem 42: 2498-503 (1999)


Article DOI: 10.1021/jm990073x
BindingDB Entry DOI: 10.7270/Q2639NZB
More data for this
Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI)


(Homo sapiens (Human))
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.24E+4n/an/an/an/an/an/a



Ataturk University



Assay Description
Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...


J Enzyme Inhib Med Chem 27: 818-24 (2012)


Article DOI: 10.3109/14756366.2011.617745
BindingDB Entry DOI: 10.7270/Q2G73CKP
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 612n/an/an/an/an/an/a



Ataturk University



Assay Description
Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...


J Enzyme Inhib Med Chem 27: 818-24 (2012)


Article DOI: 10.3109/14756366.2011.617745
BindingDB Entry DOI: 10.7270/Q2G73CKP
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (human))
BDBM50465
PNG
(MLS000673672 | N-[4-(dimethylamino)phenyl]-4-methy...)
Show SMILES CN(C)c1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C15H18N2O2S/c1-12-4-10-15(11-5-12)20(18,19)16-13-6-8-14(9-7-13)17(2)3/h4-11,16H,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

PCBioAssay
n/an/a 1.07E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q23X8539
More data for this
Ligand-Target Pair
transient receptor potential cation channel, subfamily N, member 1


(Danio rerio)
BDBM46877
PNG
(MLS000530990 | N,4-dimethyl-N-(4-methylphenyl)benz...)
Show SMILES CN(c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C15H17NO2S/c1-12-4-8-14(9-5-12)16(3)19(17,18)15-10-6-13(2)7-11-15/h4-11H,1-3H3
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/an/an/a 2.99E+4n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2Z60MG3
More data for this
Ligand-Target Pair
MCOLN3 protein


(Homo sapiens)
BDBM46877
PNG
(MLS000530990 | N,4-dimethyl-N-(4-methylphenyl)benz...)
Show SMILES CN(c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1
Show InChI InChI=1S/C15H17NO2S/c1-12-4-8-14(9-5-12)16(3)19(17,18)15-10-6-13(2)7-11-15/h4-11H,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/an/an/a 5.10E+3n/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q21834W4
More data for this
Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme


(Homo sapiens)
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/a>1.00E+5n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q2CR5RRG
More data for this
Ligand-Target Pair
Carbonic anhydrase 1


(Homo sapiens (human))
BDBM45795
PNG
(4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Show InChI InChI=1S/C17H15NO2S/c1-13-6-10-17(11-7-13)21(19,20)18-16-9-8-14-4-2-3-5-15(14)12-16/h2-12,18H,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.22E+5n/an/an/an/an/an/a



Ataturk University



Assay Description
Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...


J Enzyme Inhib Med Chem 27: 818-24 (2012)


Article DOI: 10.3109/14756366.2011.617745
BindingDB Entry DOI: 10.7270/Q2G73CKP
More data for this
Ligand-Target Pair