BindingDB logo
myBDB logout

26 similar compounds to monomer 109265

Compile data set for download or QSAR
Wt: 293.4
BDBM109238
Wt: 307.4
BDBM109239
Wt: 279.3
BDBM109237
Wt: 295.3
BDBM109243
Wt: 309.4
BDBM109244
Wt: 293.4
BDBM109245
Wt: 293.4
BDBM109246
Wt: 291.3
BDBM109247
Wt: 291.3
BDBM109248
Wt: 279.3
BDBM109240
Wt: 265.3
BDBM109241
Wt: 277.3
BDBM109242
Wt: 331.4
BDBM109249
Wt: 293.4
BDBM109251
Wt: 293.4
BDBM109252
Displayed 1 to 15 (of 26 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 109238,109239,109237,109243,109244,109245,109246,109247,109248,109240,109241,109242,109249,109251,109252   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109237
PNG
(US8609710, 1)
Show SMILES NCCCC(Cc1cn(cn1)C1CCCCC1)C(O)=O
Show InChI InChI=1S/C15H25N3O2/c16-8-4-5-12(15(19)20)9-13-10-18(11-17-13)14-6-2-1-3-7-14/h10-12,14H,1-9,16H2,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 21n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109252
PNG
(US8609710, 15 (2S form))
Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(C[C@H](CCCN)C(O)=O)c1
Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13-,15-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 7.80n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109239
PNG
(US8609710, 3)
Show SMILES CC[C@H]1CC[C@@H](CC1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C17H29N3O2/c1-2-13-5-7-16(8-6-13)20-11-15(19-12-20)10-14(17(21)22)4-3-9-18/h11-14,16H,2-10,18H2,1H3,(H,21,22)/t13-,14?,16-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.80n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109240
PNG
(US8609710, 4)
Show SMILES CCC1CC(C1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C15H25N3O2/c1-2-11-6-14(7-11)18-9-13(17-10-18)8-12(15(19)20)4-3-5-16/h9-12,14H,2-8,16H2,1H3,(H,19,20)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109241
PNG
(US8609710, 5)
Show SMILES CC1CC(C1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C14H23N3O2/c1-10-5-13(6-10)17-8-12(16-9-17)7-11(14(18)19)3-2-4-15/h8-11,13H,2-7,15H2,1H3,(H,18,19)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 35n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109242
PNG
(US8609710, 6)
Show SMILES NCCCC(Cc1cn(cn1)[C@H]1C[C@@H]2C[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C15H23N3O2/c16-3-1-2-10(15(19)20)5-13-8-18(9-17-13)14-6-11-4-12(11)7-14/h8-12,14H,1-7,16H2,(H,19,20)/t10?,11-,12+,14-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 21n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109243
PNG
(US8609710, 7)
Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC[C@H](O)CC1)C(O)=O
Show InChI InChI=1S/C15H25N3O3/c16-7-1-2-11(15(20)21)8-12-9-18(10-17-12)13-3-5-14(19)6-4-13/h9-11,13-14,19H,1-8,16H2,(H,20,21)/t11?,13-,14-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 26n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109244
PNG
(US8609710, 8)
Show SMILES CC1(O)CCC(CC1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C16H27N3O3/c1-16(22)6-4-14(5-7-16)19-10-13(18-11-19)9-12(15(20)21)3-2-8-17/h10-12,14,22H,2-9,17H2,1H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 19n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109245
PNG
(US8609710, 9)
Show SMILES CC1CCCC(C1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C16H27N3O2/c1-12-4-2-6-15(8-12)19-10-14(18-11-19)9-13(16(20)21)5-3-7-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 18n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109246
PNG
(US8609710, 10)
Show SMILES NCCCC(Cc1cn(cn1)C1CCCCCC1)C(O)=O
Show InChI InChI=1S/C16H27N3O2/c17-9-5-6-13(16(20)21)10-14-11-19(12-18-14)15-7-3-1-2-4-8-15/h11-13,15H,1-10,17H2,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 21n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109247
PNG
(US8609710, 11)
Show SMILES NCCCC(Cc1cn(cn1)[C@@H]1CC2CCC1C2)C(O)=O
Show InChI InChI=1S/C16H25N3O2/c17-5-1-2-13(16(20)21)8-14-9-19(10-18-14)15-7-11-3-4-12(15)6-11/h9-13,15H,1-8,17H2,(H,20,21)/t11?,12?,13?,15-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 14n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109248
PNG
(US8609710, 12)
Show SMILES NCCCC(Cc1cn(cn1)[C@H]1CC2CCC1C2)C(O)=O
Show InChI InChI=1S/C16H25N3O2/c17-5-1-2-13(16(20)21)8-14-9-19(10-18-14)15-7-11-3-4-12(15)6-11/h9-13,15H,1-8,17H2,(H,20,21)/t11?,12?,13?,15-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 25n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109249
PNG
(US8609710, 13)
Show SMILES NCCCC(Cc1cn(cn1)C1C2CC3CC(C2)CC1C3)C(O)=O
Show InChI InChI=1S/C19H29N3O2/c20-3-1-2-14(19(23)24)9-17-10-22(11-21-17)18-15-5-12-4-13(7-15)8-16(18)6-12/h10-16,18H,1-9,20H2,(H,23,24)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 12n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109251
PNG
(US8609710, 15 (2R form))
Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(C[C@@H](CCCN)C(O)=O)c1
Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13-,15-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>100n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair
Thrombin-activable fibrinolysis inhibitor (TAFIa)


(Homo sapiens (Human))
BDBM109238
PNG
(US8609710, 2)
Show SMILES C[C@H]1CC[C@@H](CC1)n1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C16H27N3O2/c1-12-4-6-15(7-5-12)19-10-14(18-11-19)9-13(16(20)21)3-2-8-17/h10-13,15H,2-9,17H2,1H3,(H,20,21)/t12-,13?,15-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8.30n/an/an/an/an/an/a



Daiichi Sankyo Company, Limited

US Patent


Assay Description
Enzyme inhibition assay using TAFIa.


US Patent US8609710 (2013)


BindingDB Entry DOI: 10.7270/Q2KW5DPP
More data for this
Ligand-Target Pair