BindingDB logo
myBDB logout

6 similar compounds to monomer 109467

Compile data set for download or QSAR
Wt: 258.2
BDBM109405
Wt: 272.2
BDBM109439
Wt: 286.2
BDBM109448
Wt: 272.2
BDBM109456
Wt: 286.2
BDBM109457
Wt: 397.3
BDBM109431

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 109405,109439,109448,109456,109457,109431   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM109439
PNG
(US8604061, 165)
Show SMILES CC(C[C@H]1COC(N)=N1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C13H15F3N2O/c1-8(6-11-7-19-12(17)18-11)9-2-4-10(5-3-9)13(14,15)16/h2-5,8,11H,6-7H2,1H3,(H2,17,18)/t8?,11-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
1.20n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay using TAAR1.


US Patent US8604061 (2013)


BindingDB Entry DOI: 10.7270/Q22V2DRF
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM109405
PNG
(US8604061, 120)
Show SMILES NC1=N[C@@H](CCc2cccc(c2)C(F)(F)F)CO1
Show InChI InChI=1/C12H13F3N2O/c13-12(14,15)9-3-1-2-8(6-9)4-5-10-7-18-11(16)17-10/h1-3,6,10H,4-5,7H2,(H2,16,17)/t10-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
1.40n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay using TAAR1.


US Patent US8604061 (2013)


BindingDB Entry DOI: 10.7270/Q22V2DRF
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM109456
PNG
(US8604061, 193)
Show SMILES CC(C[C@H]1COC(N)=N1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1/C13H15F3N2O/c1-8(5-11-7-19-12(17)18-11)9-3-2-4-10(6-9)13(14,15)16/h2-4,6,8,11H,5,7H2,1H3,(H2,17,18)/t8?,11-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
4.30n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay using TAAR1.


US Patent US8604061 (2013)


BindingDB Entry DOI: 10.7270/Q22V2DRF
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM109448
PNG
(US8604061, 184)
Show SMILES CCC(C[C@H]1COC(N)=N1)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C14H17F3N2O/c1-2-9(7-12-8-20-13(18)19-12)10-3-5-11(6-4-10)14(15,16)17/h3-6,9,12H,2,7-8H2,1H3,(H2,18,19)/t9?,12-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
6.30n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay using TAAR1.


US Patent US8604061 (2013)


BindingDB Entry DOI: 10.7270/Q22V2DRF
More data for this
Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM109457
PNG
(US8604061, 194)
Show SMILES CCC(C[C@H]1COC(N)=N1)c1cccc(c1)C(F)(F)F
Show InChI InChI=1/C14H17F3N2O/c1-2-9(7-12-8-20-13(18)19-12)10-4-3-5-11(6-10)14(15,16)17/h3-6,9,12H,2,7-8H2,1H3,(H2,18,19)/t9?,12-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
7.30n/an/an/an/an/an/an/an/a



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay using TAAR1.


US Patent US8604061 (2013)


BindingDB Entry DOI: 10.7270/Q22V2DRF
More data for this
Ligand-Target Pair
HIF-PH2


(Homo sapiens (Human))
BDBM109431
PNG
(US9695170 140)
Show SMILES COc1cc2c(O)c(ncc2n(Cc2ccccc2)c1=O)C(=O)NCCC(O)=O
Show InChI InChI=1S/C20H19N3O6/c1-29-15-9-13-14(23(20(15)28)11-12-5-3-2-4-6-12)10-22-17(18(13)26)19(27)21-8-7-16(24)25/h2-6,9-10,26H,7-8,11H2,1H3,(H,21,27)(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.20E+3n/an/an/an/a7.4n/a



FibroGen Inc

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...


US Patent US9695170 (2017)


BindingDB Entry DOI: 10.7270/Q2P55KN0
More data for this
Ligand-Target Pair