BindingDB logo
myBDB logout

1 similar compounds to monomer 130199

Compile data set for download or QSAR
Wt: 418.8
BDBM130215

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130215   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-secretase 2


(Homo sapiens (Human))
BDBM130215
PNG
(US8815881, 150)
Show SMILES COc1ccc(Cl)cc1Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)N(C)C(=O)C1(C)C
Show InChI InChI=1S/C21H24ClFN4O2/c1-20(2)18(28)27(4)19(24)26-21(20,3)14-11-13(7-8-15(14)23)25-16-10-12(22)6-9-17(16)29-5/h6-11,25H,1-5H3,(H2,24,26)/t21-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 21n/an/an/an/an/a4



Hoffmann-La Roche Inc.; Siena Biotech S.p.A.

US Patent


Assay Description
BACE2 enzyme ectodomain (derived from plasmid pET17b-T7-hu proBACE2) was prepared as described in Ostermann et al., Crystal Structure of Human BACE2 ...


US Patent US8815881 (2014)


BindingDB Entry DOI: 10.7270/Q2NZ86B5
More data for this
Ligand-Target Pair