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1 similar compounds to monomer 50412079

Compile data set for download or QSAR
Wt: 263.3
BDBM1396

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1396   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HIV-1 Reverse Transcriptase


(Human immunodeficiency virus type 1)
BDBM1396
PNG
(1,2,3,10b-Tetrahydropyrido[2,1-a]isoindol-6(2H)-on...)
Show SMILES O=C1N2CCCCC2(c2ccccc12)c1ccccc1
Show InChI InChI=1S/C18H17NO/c20-17-15-10-4-5-11-16(15)18(12-6-7-13-19(17)18)14-8-2-1-3-9-14/h1-5,8-11H,6-7,12-13H2
PDB
MMDB

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.55E+4n/an/an/an/an/an/a



Boehringer Mannheim GmbH



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 36: 2526-35 (1993)


Article DOI: 10.1021/jm00069a011
BindingDB Entry DOI: 10.7270/Q2BR8QCZ
More data for this
Ligand-Target Pair