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9 similar compounds to monomer 152536

Compile data set for download or QSAR
Wt: 318.3
BDBM152537
Wt: 318.3
BDBM152538
Wt: 334.3
BDBM152544
Wt: 322.2
BDBM152539
Wt: 322.2
BDBM152540
Wt: 338.7
BDBM152541
Wt: 338.7
BDBM152542
Wt: 334.3
BDBM152543
Wt: 364.3
BDBM152546

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 152537,152538,152544,152539,152540,152541,152542,152543,152546   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152537
PNG
(10-(3-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Cc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C18H14N4O2/c1-11-5-4-6-12(9-11)10-22-14-8-3-2-7-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 1.16E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152546
PNG
(10-(3,4-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Show SMILES COc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1OC
Show InChI InChI=1S/C19H16N4O4/c1-26-14-8-7-11(9-15(14)27-2)10-23-13-6-4-3-5-12(13)20-16-17(23)21-19(25)22-18(16)24/h3-9H,10H2,1-2H3,(H,22,24,25)
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n/an/a 8.55E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152539
PNG
(10-(2-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Fc1ccccc1Cn1c2ccccc2nc2c1nc(=O)[nH]c2=O
Show InChI InChI=1S/C17H11FN4O2/c18-11-6-2-1-5-10(11)9-22-13-8-4-3-7-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 7.28E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152540
PNG
(10-(3-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Fc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C17H11FN4O2/c18-11-5-3-4-10(8-11)9-22-13-7-2-1-6-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 1.15E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152541
PNG
(10-(3-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Clc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C17H11ClN4O2/c18-11-5-3-4-10(8-11)9-22-13-7-2-1-6-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 4.73E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152542
PNG
(10-(4-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Clc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C17H11ClN4O2/c18-11-7-5-10(6-8-11)9-22-13-4-2-1-3-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 3.00E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152543
PNG
(10-(2-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Show SMILES COc1ccccc1Cn1c2ccccc2nc2c1nc(=O)[nH]c2=O
Show InChI InChI=1S/C18H14N4O3/c1-25-14-9-5-2-6-11(14)10-22-13-8-4-3-7-12(13)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 1.88E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152544
PNG
(10-(4-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Show SMILES COc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C18H14N4O3/c1-25-12-8-6-11(7-9-12)10-22-14-5-3-2-4-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 9.34E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152546
PNG
(10-(3,4-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Show SMILES COc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1OC
Show InChI InChI=1S/C19H16N4O4/c1-26-14-8-7-11(9-15(14)27-2)10-23-13-6-4-3-5-12(13)20-16-17(23)21-19(25)22-18(16)24/h3-9H,10H2,1-2H3,(H,22,24,25)
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n/an/a 3.26E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152537
PNG
(10-(3-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Cc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C18H14N4O2/c1-11-5-4-6-12(9-11)10-22-14-8-3-2-7-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 4.29E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152538
PNG
(10-(4-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Cc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C18H14N4O2/c1-11-6-8-12(9-7-11)10-22-14-5-3-2-4-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 7.89E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152539
PNG
(10-(2-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Fc1ccccc1Cn1c2ccccc2nc2c1nc(=O)[nH]c2=O
Show InChI InChI=1S/C17H11FN4O2/c18-11-6-2-1-5-10(11)9-22-13-8-4-3-7-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 2.16E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152540
PNG
(10-(3-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Fc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C17H11FN4O2/c18-11-5-3-4-10(8-11)9-22-13-7-2-1-6-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 8.26E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152541
PNG
(10-(3-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Clc1cccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)c1
Show InChI InChI=1S/C17H11ClN4O2/c18-11-5-3-4-10(8-11)9-22-13-7-2-1-6-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 1.05E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152542
PNG
(10-(4-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Clc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C17H11ClN4O2/c18-11-7-5-10(6-8-11)9-22-13-4-2-1-3-12(13)19-14-15(22)20-17(24)21-16(14)23/h1-8H,9H2,(H,21,23,24)
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n/an/a 7.39E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152543
PNG
(10-(2-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Show SMILES COc1ccccc1Cn1c2ccccc2nc2c1nc(=O)[nH]c2=O
Show InChI InChI=1S/C18H14N4O3/c1-25-14-9-5-2-6-11(14)10-22-13-8-4-3-7-12(13)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 8.39E+3n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Butyrylcholinesterase (BChE)


(Equus caballus (Horse))
BDBM152544
PNG
(10-(4-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Show SMILES COc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C18H14N4O3/c1-25-12-8-6-11(7-9-12)10-22-14-5-3-2-4-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 4.72E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair
Acetylcholinesterase


(Homo sapiens (Human))
BDBM152538
PNG
(10-(4-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Show SMILES Cc1ccc(Cn2c3ccccc3nc3c2nc(=O)[nH]c3=O)cc1
Show InChI InChI=1S/C18H14N4O2/c1-11-6-8-12(9-7-11)10-22-14-5-3-2-4-13(14)19-15-16(22)20-18(24)21-17(15)23/h2-9H,10H2,1H3,(H,21,23,24)
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n/an/a 2.94E+4n/an/an/an/a8.025



The M. S. University of Baroda



Assay Description
Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...


Bioorg Chem 61: 7-12 (2015)


Article DOI: 10.1016/j.bioorg.2015.05.005
BindingDB Entry DOI: 10.7270/Q2WS8S05
More data for this
Ligand-Target Pair