Wt: 482.5 BDBM17054 ![]() | Wt: 570.6 BDBM31094 ![]() | Wt: 466.5 BDBM32337 ![]() | Wt: 466.5 BDBM50059889 ![]() | Wt: 482.5 BDBM50280450 ![]() |
Wt: 508.5 BDBM50283893 ![]() | Wt: 480.5 BDBM50283894 ![]() | Wt: 495.5 BDBM50283895 ![]() | Wt: 544.6 BDBM50283896 ![]() | Wt: 605.0 BDBM50283897 ![]() |
Wt: 605.0 BDBM50283898 ![]() | Wt: 509.6 BDBM50283899 ![]() | Wt: 494.5 BDBM50283900 ![]() | Wt: 623.6 BDBM50283901 ![]() | Wt: 556.6 BDBM50283902 ![]() |
Displayed 1 to 15 (of 47 total ) | Next | Last >> |
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50059889![]() ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human N-terminal His-tagged non-phosphorylated VEGFR2 after 10 mins by Global fit analysis | Bioorg Med Chem 19: 5342-51 (2011) Article DOI: 10.1016/j.bmc.2011.08.002 BindingDB Entry DOI: 10.7270/Q21R6QW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 5.60 | -11.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
GlaxoSmithKline | Assay Description In vitro Chk1 enzymatic assay using purified enzyme, was incubated with substrate, and test compounds in the presence of 10 uM ATP/ [gamma-32P] ATP. ... | J Biol Chem 277: 46609-15 (2002) Article DOI: 10.1074/jbc.M201233200 BindingDB Entry DOI: 10.7270/Q2D798PF | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50059889![]() ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vertex Pharmaceuticals Inc Curated by ChEMBL | Assay Description Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay | Bioorg Med Chem Lett 20: 1661-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.072 BindingDB Entry DOI: 10.7270/Q2TX3G9B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-Dependent Kinase 2 (CDK2) (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 30 | -10.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
GlaxoSmithKline | Assay Description In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ... | J Biol Chem 277: 46609-15 (2002) Article DOI: 10.1074/jbc.M201233200 BindingDB Entry DOI: 10.7270/Q2D798PF | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-Dependent Kinase 1 (CDK1) (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 95 | -9.48 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
GlaxoSmithKline | Assay Description In vitro CDK enzymatic assay using purified CDK mixed with cyclin A, was incubated with substrate, and test compounds in the presence of 1.4 uM ATP/ ... | J Biol Chem 277: 46609-15 (2002) Article DOI: 10.1074/jbc.M201233200 BindingDB Entry DOI: 10.7270/Q2D798PF | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Cyclin-Dependent Kinase 4 (CDK4) (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.60E+3 | -7.55 | n/a | n/a | n/a | n/a | n/a | 7.5 | 30 |
GlaxoSmithKline | Assay Description CDK4 and cyclin D1 were expressed in a baculovirus expression system and subsequently purified. The catalytic activity of the CDK4 protein was assaye... | J Biol Chem 277: 46609-15 (2002) Article DOI: 10.1074/jbc.M201233200 BindingDB Entry DOI: 10.7270/Q2D798PF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 7.70E+3 | -6.97 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK3 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GB22FT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GCN2(Kin.Dom.2 S808G) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q28W3BP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 9.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M32T55 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 1.50E+5 | -5.21 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 2.20E+5 | -4.99 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Non-receptor tyrosine-protein kinase TYK2 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2TD9VQC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha 1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 6.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2959FZG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 7.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25D8Q75 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 7.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21N7ZHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ribosomal protein S6 kinase alpha 6 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 1.50E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2WW7G1J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | 1.60E+6 | -3.81 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human)) | BDBM50059889![]() ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyung Hee University Curated by ChEMBL | Assay Description Inhibition of CDK5/p25 (unknown origin)-mediated incorporation of gamma33P into substrate after 20 mins by scintillation counting analysis in presenc... | Bioorg Med Chem Lett 23: 5150-4 (2013) Article DOI: 10.1016/j.bmcl.2013.07.020 BindingDB Entry DOI: 10.7270/Q27M09CN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-phosphoinositide-dependent protein kinase 1 (aa 51-359) (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Dundee | Assay Description In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco... | Biochem J 375: 255-62 (2003) Article DOI: 10.1042/BJ20031119 BindingDB Entry DOI: 10.7270/Q2X928JB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
3-phosphoinositide-dependent protein kinase 1 (aa 51-359) (Homo sapiens (Human)) | BDBM17054![]() ((2S,3R,4R,6R,18R)-18-hydroxy-3-methoxy-2-methyl-4-...) | PDB GoogleScholar | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.5 | 30 |
University of Dundee | Assay Description In vitro PDK1 assay using purified enzyme, was incubated with substrate PDKtide, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P inco... | Structure 12: 215-26 (2004) Article DOI: 10.1016/j.str.2004.01.005 BindingDB Entry DOI: 10.7270/Q2SJ1HV2 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
ABL Mutant (T315I) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 270 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 120 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase B (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora Kinase C (Aurora-C) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB NCI pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 170 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage colony stimulating factor receptor (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 330 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
EGF-R Tyrosine Kinase Mutant (G719C) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase D1 (Homo sapiens (Human)) | BDBM32337![]() (MLS000028832 | SMR000058536 | STAUROSPORINE | cid_...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid PDB UniChem Patents Similars | PCBioAssay | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.2 | 23 |
University of Pittsburgh Curated by PubChem BioAssay | Assay Description The PKD HTS assay was developed and run at the University of Pittsburgh Molecular Screening Center (PMLSC) as part of the Molecular Library Screening... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2FJ2F43 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CLK1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB DrugBank GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 350 | n/a | n/a | n/a | 7.4 | 23 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein kinase CLK4 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 410 | n/a | n/a | n/a | 7.4 | 23 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine Kinase FLT3 Mutant (N841I) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 670 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase FRK (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 450 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 11 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
FLT3(D835H) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
FLT3(D835Y) (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 15 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 11 | n/a | n/a | n/a | 7.4 | 25 |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2NC5ZHH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2SX6BK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fgr (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JD4V4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Fyn (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2DN43D1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lck (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q25719CM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21G0JNW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5'-AMP-activated protein kinase catalytic subunit alpha-1 (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2M61HMX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CaM kinase I alpha (Homo sapiens (Human)) | BDBM31094![]() (PKC-412 | cid_24202429) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
Ambit Biosciences Curated by PubChem BioAssay | Assay Description Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BR8QJ6 | |||||||||||
More data for this Ligand-Target Pair |
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