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1 similar compounds to monomer 17681

Compile data set for download or QSAR
Wt: 404.7
BDBM17679

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)


(Homo sapiens (Human))
BDBM17679
PNG
(2-aminobenzimidazole, 4 | N-[4-chloro-3-(trifluoro...)
Show SMILES FC(F)(F)c1cc(Nc2nc3ccc(Oc4ccncc4)cc3[nH]2)ccc1Cl
Show InChI InChI=1S/C19H12ClF3N4O/c20-15-3-1-11(9-14(15)19(21,22)23)25-18-26-16-4-2-13(10-17(16)27-18)28-12-5-7-24-8-6-12/h1-10H,(H2,25,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
160 -9.17n/an/an/an/an/a7.522



Amgen



Assay Description
The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...


J Med Chem 50: 4351-4373 (2007)


Article DOI: 10.1021/jm070034i
BindingDB Entry DOI: 10.7270/Q21V5C74
More data for this
Ligand-Target Pair