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117 molecules are shown

Wt: 191.2
BDBM50437448
Wt: 205.2
BDBM50437449
Wt: 205.2
BDBM50437450
Wt: 191.2
BDBM50437451
Wt: 309.3
BDBM50036147
Wt: 309.3
BDBM50036139
Wt: 358.4
BDBM50024130
Wt: 251.2
BDBM50024140
Purchase
Wt: 291.3
BDBM50024127
Wt: 289.3
BDBM50024114
Wt: 291.3
BDBM50024119
Wt: 275.3
BDBM50024117
<<  First   |  Previous   |  Displayed 106 to 117 (of 117 total )

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50437448,50437449,50437450,50437451,50036147,50036139,50024130,50024140,50024127,50024114,50024119,50024117   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50437448
PNG
(CHEMBL2409344)
Show SMILES CC[C@@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(3-10)9-4/h4-13H,2-3H2,1H3/t4-,5-,6-,7+,8+/m0/s1
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n/an/a 7.20E+4n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair
Dopamine receptor


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)
BDBM50024130
PNG
(CHEMBL46911)
Show SMILES Cc1nn(C)c(NC(=O)CCN2CCCC2)c1C(=O)c1ccccc1F
Show InChI InChI=1S/C10H21NO6/c12-2-5-1-7(11-6(3-13)4-14)9(16)10(17)8(5)15/h5-17H,1-4H2/t5?,7-,8+,9?,10+/m0/s1
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n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity for dopamine receptor in rat striatal membrane using [3H]haloperidol as radioligand


J Med Chem 29: 1628-37 (1986)


Article DOI: 10.1021/jm00159a011
BindingDB Entry DOI: 10.7270/Q2319TVF
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50437450
PNG
(CHEMBL2409346)
Show SMILES CCC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C9H19NO4/c1-2-3-5-7(12)9(14)8(13)6(11)4-10-5/h5-14H,2-4H2,1H3/t5-,6+,7-,8+,9+/m0/s1
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n/an/a 5.41E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50437451
PNG
(CHEMBL2409348)
Show SMILES CC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(10)3-9-4/h4-13H,2-3H2,1H3/t4-,5+,6-,7+,8+/m0/s1
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n/an/a 5.26E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair
Glucosylceramidase


(Bos taurus)
BDBM50437451
PNG
(CHEMBL2409348)
Show SMILES CC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(10)3-9-4/h4-13H,2-3H2,1H3/t4-,5+,6-,7+,8+/m0/s1
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n/an/a 4.87E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-glucosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50036139
PNG
(CHEMBL3358660)
Show SMILES O[C@@H]1C[C@H](N[C@H]2C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5+,6+,7-,8+,9-,10+,11-,12+/m0/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50036147
PNG
(CHEMBL3358661)
Show SMILES O[C@H]1C[C@H](N[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5-,6+,7+,8-,9+,10-,11+,12-/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.09.064
BindingDB Entry DOI: 10.7270/Q2MS3VCJ
More data for this
Ligand-Target Pair
Sucrase-isomaltase


(Homo sapiens)
BDBM50024114
PNG
(5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohe...)
Show SMILES OC[C@@]1(O)C[C@H](NCC2CCCCC2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C14H27NO5/c16-8-14(20)6-10(11(17)12(18)13(14)19)15-7-9-4-2-1-3-5-9/h9-13,15-20H,1-8H2/t10-,11?,12-,13-,14?/m0/s1
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n/an/a 9.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucrase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Sucrase-isomaltase


(Homo sapiens)
BDBM50024117
PNG
(5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,...)
Show SMILES OC[C@@]1(O)C[C@H](NC2CCCCC2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO5/c15-7-13(19)6-9(10(16)11(17)12(13)18)14-8-4-2-1-3-5-8/h8-12,14-19H,1-7H2/t9-,10?,11-,12-,13?/m0/s1
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n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucrase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50024119
PNG
(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Show SMILES OC[C@@]1(O)C[C@H](N[C@@H]2CCCC[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO6/c15-6-13(20)5-8(10(17)11(18)12(13)19)14-7-3-1-2-4-9(7)16/h7-12,14-20H,1-6H2/t7-,8-,9-,10?,11-,12-,13?/m0/s1
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n/an/a 6.10n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against porcine maltase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50024127
PNG
(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Show SMILES OC[C@@]1(O)C[C@H](N[C@H]2CCCC[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO6/c15-6-13(20)5-8(10(17)11(18)12(13)19)14-7-3-1-2-4-9(7)16/h7-12,14-20H,1-6H2/t7-,8+,9?,10?,11+,12+,13?/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against porcine maltase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Sucrase-isomaltase


(Homo sapiens)
BDBM50024119
PNG
(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Show SMILES OC[C@@]1(O)C[C@H](N[C@@H]2CCCC[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO6/c15-6-13(20)5-8(10(17)11(18)12(13)19)14-7-3-1-2-4-9(7)16/h7-12,14-20H,1-6H2/t7-,8-,9-,10?,11-,12-,13?/m0/s1
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n/an/a 5.20n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucrase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50024114
PNG
(5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohe...)
Show SMILES OC[C@@]1(O)C[C@H](NCC2CCCCC2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C14H27NO5/c16-8-14(20)6-10(11(17)12(18)13(14)19)15-7-9-4-2-1-3-5-9/h9-13,15-20H,1-8H2/t10-,11?,12-,13-,14?/m0/s1
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n/an/a 240n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against porcine maltase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Sucrase-isomaltase


(Homo sapiens)
BDBM50024140
PNG
(5-(2-Hydroxy-1-hydroxymethyl-ethylamino)-1-hydroxy...)
Show SMILES OCC(CO)N[C@H]1C[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7?,8-,9-,10?/m0/s1
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n/an/a 180n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucrase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Sucrase-isomaltase


(Homo sapiens)
BDBM50024127
PNG
(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Show SMILES OC[C@@]1(O)C[C@H](N[C@H]2CCCC[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO6/c15-6-13(20)5-8(10(17)11(18)12(13)19)14-7-3-1-2-4-9(7)16/h7-12,14-20H,1-6H2/t7-,8+,9?,10?,11+,12+,13?/m1/s1
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n/an/a 160n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucrase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50024117
PNG
(5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,...)
Show SMILES OC[C@@]1(O)C[C@H](NC2CCCCC2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C13H25NO5/c15-7-13(19)6-9(10(16)11(17)12(13)18)14-8-4-2-1-3-5-8/h8-12,14-19H,1-7H2/t9-,10?,11-,12-,13?/m0/s1
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n/an/a 410n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against porcine maltase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50024140
PNG
(5-(2-Hydroxy-1-hydroxymethyl-ethylamino)-1-hydroxy...)
Show SMILES OCC(CO)N[C@H]1C[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7?,8-,9-,10?/m0/s1
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n/an/a 550n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against porcine maltase


J Med Chem 29: 1038-46 (1986)


Article DOI: 10.1021/jm00156a023
BindingDB Entry DOI: 10.7270/Q27P8ZZV
More data for this
Ligand-Target Pair
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50437449
PNG
(CHEMBL2409342)
Show SMILES CCC[C@@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C9H19NO4/c1-2-3-5-7(12)9(14)8(13)6(4-11)10-5/h5-14H,2-4H2,1H3/t5-,6-,7-,8+,9+/m0/s1
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n/an/a 7.13E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)


Article DOI: 10.1016/j.bmc.2013.03.035
BindingDB Entry DOI: 10.7270/Q2GQ7053
More data for this
Ligand-Target Pair