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117 molecules are shown

Wt: 193.1
BDBM50408433
Wt: 193.1
BDBM50403720
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Wt: 163.1
BDBM50403110
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Wt: 163.1
BDBM50403114
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Wt: 231.3
BDBM50442352
Wt: 191.2
BDBM50437447
Wt: 191.2
BDBM50437448
Wt: 205.2
BDBM50437449
Wt: 205.2
BDBM50437450
Wt: 191.2
BDBM50437451
Wt: 309.3
BDBM50036147
Wt: 309.3
BDBM50036139
<<  First   |  Previous   |  Displayed 106 to 117 (of 117 total )

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50408433,50403720,50403110,50403114,50442352,50437447,50437448,50437449,50437450,50437451,50036147,50036139   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50403114
PNG
(CHEMBL1337303)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5+,6-/m1/s1
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5.30E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Alpha-Fucosidase


Bioorg Med Chem Lett 2: 33-36 (1992)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50403110
PNG
(CHEMBL179085)
Show SMILES OC[C@@H]1NC[C@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m0/s1
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9.00E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition constant against Alpha-Fucosidase


Bioorg Med Chem Lett 2: 33-36 (1992)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50437449
PNG
(CHEMBL2409342)
Show SMILES CCC[C@@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C9H19NO4/c1-2-3-5-7(12)9(14)8(13)6(4-11)10-5/h5-14H,2-4H2,1H3/t5-,6-,7-,8+,9+/m0/s1
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n/an/a 7.13E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50437450
PNG
(CHEMBL2409346)
Show SMILES CCC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C9H19NO4/c1-2-3-5-7(12)9(14)8(13)6(11)4-10-5/h5-14H,2-4H2,1H3/t5-,6+,7-,8+,9+/m0/s1
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n/an/a 5.41E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50437451
PNG
(CHEMBL2409348)
Show SMILES CC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(10)3-9-4/h4-13H,2-3H2,1H3/t4-,5+,6-,7+,8+/m0/s1
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n/an/a 5.26E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-galactosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair
Glucosylceramidase


(Bos taurus)
BDBM50437451
PNG
(CHEMBL2409348)
Show SMILES CC[C@@H]1NC[C@@H](O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(10)3-9-4/h4-13H,2-3H2,1H3/t4-,5+,6-,7+,8+/m0/s1
PDB
MMDB

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n/an/a 4.87E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine liver beta-glucosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair
Neutral alpha-glucosidase C


(Mus musculus)
BDBM50403720
PNG
(CHEMBL2111688)
Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7-/m1/s1
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n/an/a<5.00E+4n/an/an/an/an/an/a



Institut de Chimie Organique et Analytique (I.C.O.A.)

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-glucosidase from rat intestinal maltase at concentration 1 mM


Citation and Details
More data for this
Ligand-Target Pair
β-galactosidase


(Bos taurus (Bovine))
BDBM50403720
PNG
(CHEMBL2111688)
Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7-/m1/s1
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n/an/a 1.60E+5n/an/an/an/an/an/a



Institut de Chimie Organique et Analytique (I.C.O.A.)

Curated by ChEMBL


Assay Description
Inhibitory activity against beta-galactosidase from bovine liver


Citation and Details
More data for this
Ligand-Target Pair
Neutral alpha-glucosidase C


(Homo sapiens)
BDBM50403720
PNG
(CHEMBL2111688)
Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7-/m1/s1
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n/an/a 8.00E+4n/an/an/an/an/an/a



Institut de Chimie Organique et Analytique (I.C.O.A.)

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-galactosidase from coffee bean.


Citation and Details
More data for this
Ligand-Target Pair
Alpha-galactosidase A


(Rattus norvegicus)
BDBM50403720
PNG
(CHEMBL2111688)
Show SMILES OC[C@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4-,5-,6+,7-/m1/s1
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n/an/a 6.70E+4n/an/an/an/an/an/a



Institut de Chimie Organique et Analytique (I.C.O.A.)

Curated by ChEMBL


Assay Description
Inhibitory activity against alpha-galactosidase from rat epididymis.


Citation and Details
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50408433
PNG
(CHEMBL2093897)
Show SMILES OC[C@H]1N[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4+,5-,6+,7+
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n/an/a 8.20E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibitory activity measured against alpha-glucosidase of rat liver lysosomal by colorimetric assay using the D-glucose oxidase-peroxidase method


J Med Chem 41: 2565-71 (1998)

More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50408433
PNG
(CHEMBL2093897)
Show SMILES OC[C@H]1N[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4+,5-,6+,7+
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n/an/a 1.50E+4n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibitory activity measured against alpha-glucosidase of rat intestinal maltase by colorimetric assay using the D-glucose oxidase-peroxidase method


J Med Chem 41: 2565-71 (1998)

More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50036139
PNG
(CHEMBL3358660)
Show SMILES O[C@@H]1C[C@H](N[C@H]2C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5+,6+,7-,8+,9-,10+,11-,12+/m0/s1
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n/an/a 3.70E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)

More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Rattus norvegicus (Rat))
BDBM50036147
PNG
(CHEMBL3358661)
Show SMILES O[C@H]1C[C@H](N[C@H]2C[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H23NO8/c14-5-1-3(7(16)11(20)9(5)18)13-4-2-6(15)10(19)12(21)8(4)17/h3-21H,1-2H2/t3-,4-,5-,6+,7+,8-,9+,10-,11+,12-/m0/s1
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n/an/a 4.00E+3n/an/an/an/an/an/a



Chulalongkorn University

Curated by ChEMBL


Assay Description
Inhibition of rat intestinal sucrase using sucrose substrate incubated for 10 mins


Bioorg Med Chem Lett 24: 5530-3 (2014)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Homo sapiens)
BDBM50442352
PNG
(CHEMBL2442775)
Show SMILES CCCCCC[C@H]1N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H25NO3/c1-3-4-5-6-7-9-11(15)12(16)10(14)8(2)13-9/h8-16H,3-7H2,1-2H3/t8-,9+,10+,11+,12+/m0/s1
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n/an/a 890n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of human lysosome alpha-L-fucosidase using 4-methylumbelliferyl-alpha-L-fucopyranoside by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase I


(Rattus norvegicus)
BDBM50442352
PNG
(CHEMBL2442775)
Show SMILES CCCCCC[C@H]1N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H25NO3/c1-3-4-5-6-7-9-11(15)12(16)10(14)8(2)13-9/h8-16H,3-7H2,1-2H3/t8-,9+,10+,11+,12+/m0/s1
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n/an/a 4.10E+3n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of rat epididymis alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50442352
PNG
(CHEMBL2442775)
Show SMILES CCCCCC[C@H]1N[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C12H25NO3/c1-3-4-5-6-7-9-11(15)12(16)10(14)8(2)13-9/h8-16H,3-7H2,1-2H3/t8-,9+,10+,11+,12+/m0/s1
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n/an/a 1.40E+3n/an/an/an/an/an/a



University of Toyama

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase assessed as inhibition of release of p-nitrophenol by spectrophotometry


Bioorg Med Chem 21: 6565-73 (2013)

More data for this
Ligand-Target Pair
Alpha-mannosidase 2C1


(Rattus norvegicus)
BDBM50403114
PNG
(CHEMBL1337303)
Show SMILES OC[C@H]1NC[C@@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5+,6-/m1/s1
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n/an/a 1.50E+5n/an/an/an/an/an/a



CSIRO Division of Chemicals and Polymers

Curated by ChEMBL


Assay Description
Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)


Citation and Details
More data for this
Ligand-Target Pair
Acidic alpha-glucosidase


(Rattus norvegicus)
BDBM50408433
PNG
(CHEMBL2093897)
Show SMILES OC[C@H]1N[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4+,5-,6+,7+
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n/an/a 7.20E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibitory activity measured against alpha-glucosidase of rat intestinal sucrase by colorimetric assay using the D-glucose oxidase-peroxidase method


J Med Chem 41: 2565-71 (1998)

More data for this
Ligand-Target Pair
Maltase-glucoamylase


(Homo sapiens (Human))
BDBM50408433
PNG
(CHEMBL2093897)
Show SMILES OC[C@H]1N[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C7H15NO5/c9-1-3-5(11)7(13)6(12)4(2-10)8-3/h3-13H,1-2H2/t3-,4+,5-,6+,7+
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n/an/a 8.40E+3n/an/an/an/an/an/a



Hokuriku University

Curated by ChEMBL


Assay Description
Inhibitory activity measured against alpha-glucosidase of rice by colorimetric assay using the D-glucose oxidase-peroxidase method


J Med Chem 41: 2565-71 (1998)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50437447
PNG
(CHEMBL2409343)
Show SMILES CC[C@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(3-10)9-4/h4-13H,2-3H2,1H3/t4-,5+,6+,7-,8-/m1/s1
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n/an/a 2.08E+5n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair
Alpha-L-fucosidase 1


(Bos taurus)
BDBM50437448
PNG
(CHEMBL2409344)
Show SMILES CC[C@@H]1N[C@@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C8H17NO4/c1-2-4-6(11)8(13)7(12)5(3-10)9-4/h4-13H,2-3H2,1H3/t4-,5-,6-,7+,8+/m0/s1
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n/an/a 7.20E+4n/an/an/an/an/an/a



Universit£ de Poitiers

Curated by ChEMBL


Assay Description
Inhibition of bovine kidney alpha-L-fucosidase


Bioorg Med Chem 21: 4803-12 (2013)

More data for this
Ligand-Target Pair