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32 similar compounds to monomer 50303565

Compile data set for download or QSAR
Wt: 354.4
BDBM21311
Purchase
Wt: 370.4
BDBM21312
Wt: 370.4
BDBM21313
Wt: 310.3
BDBM71639
Purchase
Wt: 378.5
BDBM50303576
Wt: 366.4
BDBM50303577
Wt: 382.5
BDBM50303580
Wt: 368.5
BDBM50303581
Wt: 354.4
BDBM50303582
Wt: 340.4
BDBM50303583
Wt: 312.4
BDBM50303520
Wt: 326.4
BDBM50303521
Wt: 352.4
BDBM50303522
Wt: 366.4
BDBM50303523
Wt: 283.4
BDBM50303524
Displayed 1 to 15 (of 32 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 54 hits for monomerid = 21311,21312,21313,71639,50303576,50303577,50303580,50303581,50303582,50303583,50303520,50303521,50303522,50303523,50303524   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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4.40n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB2 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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4.40n/an/an/a 17.5n/an/an/an/a



Abbott Laboratories



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1904-12 (2008)


Article DOI: 10.1021/jm7011613
BindingDB Entry DOI: 10.7270/Q2C827K2
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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4.60n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303524
PNG
((1-Propyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C19H25NO/c1-6-11-20-12-14(13-9-7-8-10-15(13)20)16(21)17-18(2,3)19(17,4)5/h7-10,12,17H,6,11H2,1-5H3
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9.20n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303582
PNG
(CHEMBL570659 | Cycloheptyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H30N2O2/c25-22(18-7-3-1-2-4-8-18)20-17-24(21-10-6-5-9-19(20)21)12-11-23-13-15-26-16-14-23/h5-6,9-10,17-18H,1-4,7-8,11-16H2
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11n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303581
PNG
((trans-4-Ethylcyclohexyl)(1-(2-morpholinoethyl)-1H...)
Show SMILES CC[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H32N2O2/c1-2-18-7-9-19(10-8-18)23(26)21-17-25(22-6-4-3-5-20(21)22)12-11-24-13-15-27-16-14-24/h3-6,17-19H,2,7-16H2,1H3/t18-,19-
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16n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB2 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303581
PNG
((trans-4-Ethylcyclohexyl)(1-(2-morpholinoethyl)-1H...)
Show SMILES CC[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H32N2O2/c1-2-18-7-9-19(10-8-18)23(26)21-17-25(22-6-4-3-5-20(21)22)12-11-24-13-15-27-16-14-24/h3-6,17-19H,2,7-16H2,1H3/t18-,19-
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16n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303576
PNG
(CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...)
Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3
Show InChI InChI=1/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2
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22n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303577
PNG
((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....)
Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2
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35n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303522
PNG
(1-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCCC3=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H28N2O2/c1-21(2)20(22(21,3)4)19(26)16-14-24(17-9-6-5-8-15(16)17)13-12-23-11-7-10-18(23)25/h5-6,8-9,14,20H,7,10-13H2,1-4H3
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55n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21312
PNG
(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccc(O)cc23)C1(C)C
Show InChI InChI=1S/C22H30N2O3/c1-21(2)20(22(21,3)4)19(26)17-14-24(8-7-23-9-11-27-12-10-23)18-6-5-15(25)13-16(17)18/h5-6,13-14,20,25H,7-12H2,1-4H3
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92n/an/an/a>1.00E+4n/an/an/an/a



Abbott Laboratories



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1904-12 (2008)


Article DOI: 10.1021/jm7011613
BindingDB Entry DOI: 10.7270/Q2C827K2
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303583
PNG
(CHEMBL570874 | Cyclohexyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C21H28N2O2/c24-21(17-6-2-1-3-7-17)19-16-23(20-9-5-4-8-18(19)20)11-10-22-12-14-25-15-13-22/h4-5,8-9,16-17H,1-3,6-7,10-15H2
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138n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303523
PNG
(1-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3C(=O)CCC3=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H26N2O3/c1-21(2)20(22(21,3)4)19(27)15-13-23(16-8-6-5-7-14(15)16)11-12-24-17(25)9-10-18(24)26/h5-8,13,20H,9-12H2,1-4H3
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170n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303580
PNG
((trans-4-Isopropylcyclohexyl)(1-(2-morpholinoethyl...)
Show SMILES CC(C)[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C24H34N2O2/c1-18(2)19-7-9-20(10-8-19)24(27)22-17-26(23-6-4-3-5-21(22)23)12-11-25-13-15-28-16-14-25/h3-6,17-20H,7-16H2,1-2H3/t19-,20-
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190n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303582
PNG
(CHEMBL570659 | Cycloheptyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H30N2O2/c25-22(18-7-3-1-2-4-8-18)20-17-24(21-10-6-5-9-19(20)21)12-11-23-13-15-26-16-14-23/h5-6,9-10,17-18H,1-4,7-8,11-16H2
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362n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303581
PNG
((trans-4-Ethylcyclohexyl)(1-(2-morpholinoethyl)-1H...)
Show SMILES CC[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H32N2O2/c1-2-18-7-9-19(10-8-18)23(26)21-17-25(22-6-4-3-5-20(21)22)12-11-24-13-15-27-16-14-24/h3-6,17-19H,2,7-16H2,1H3/t18-,19-
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616n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303581
PNG
((trans-4-Ethylcyclohexyl)(1-(2-morpholinoethyl)-1H...)
Show SMILES CC[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H32N2O2/c1-2-18-7-9-19(10-8-18)23(26)21-17-25(22-6-4-3-5-20(21)22)12-11-24-13-15-27-16-14-24/h3-6,17-19H,2,7-16H2,1H3/t18-,19-
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616n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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845n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Displacement of [3H]CP 55940 from human CB1 receptor in cell free system


Eur J Med Chem 46: 547-55 (2011)


Article DOI: 10.1016/j.ejmech.2010.11.034
BindingDB Entry DOI: 10.7270/Q2CF9QCJ
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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845n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1904-12 (2008)


Article DOI: 10.1021/jm7011613
BindingDB Entry DOI: 10.7270/Q2C827K2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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945n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303521
PNG
(CHEMBL584534 | Cyclopentyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C20H26N2O2/c23-20(16-5-1-2-6-16)18-15-22(19-8-4-3-7-17(18)19)10-9-21-11-13-24-14-12-21/h3-4,7-8,15-16H,1-2,5-6,9-14H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303520
PNG
(CHEMBL571346 | Cyclobutyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C19H24N2O2/c22-19(15-4-3-5-15)17-14-21(18-7-2-1-6-16(17)18)9-8-20-10-12-23-13-11-20/h1-2,6-7,14-15H,3-5,8-13H2
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>1.00E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303583
PNG
(CHEMBL570874 | Cyclohexyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C21H28N2O2/c24-21(17-6-2-1-3-7-17)19-16-23(20-9-5-4-8-18(19)20)11-10-22-12-14-25-15-13-22/h4-5,8-9,16-17H,1-3,6-7,10-15H2
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1.63E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303577
PNG
((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....)
Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2
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3.09E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303524
PNG
((1-Propyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclop...)
Show SMILES CCCn1cc(C(=O)C2C(C)(C)C2(C)C)c2ccccc12
Show InChI InChI=1S/C19H25NO/c1-6-11-20-12-14(13-9-7-8-10-15(13)20)16(21)17-18(2,3)19(17,4)5/h7-10,12,17H,6,11H2,1-5H3
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4.30E+3n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303522
PNG
(1-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCCC3=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H28N2O2/c1-21(2)20(22(21,3)4)19(26)16-14-24(17-9-6-5-8-15(16)17)13-12-23-11-7-10-18(23)25/h5-6,8-9,14,20H,7,10-13H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21313
PNG
(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3cc(O)ccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O3/c1-21(2)20(22(21,3)4)19(26)17-14-24(8-7-23-9-11-27-12-10-23)18-13-15(25)5-6-16(17)18/h5-6,13-14,20,25H,7-12H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1904-12 (2008)


Article DOI: 10.1021/jm7011613
BindingDB Entry DOI: 10.7270/Q2C827K2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21312
PNG
(1-[2-(morpholin-4-yl)ethyl]-3-[(2,2,3,3-tetramethy...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccc(O)cc23)C1(C)C
Show InChI InChI=1S/C22H30N2O3/c1-21(2)20(22(21,3)4)19(26)17-14-24(8-7-23-9-11-27-12-10-23)18-6-5-15(25)13-16(17)18/h5-6,13-14,20,25H,7-12H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories



Assay Description
IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...


J Med Chem 51: 1904-12 (2008)


Article DOI: 10.1021/jm7011613
BindingDB Entry DOI: 10.7270/Q2C827K2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303576
PNG
(CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...)
Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3
Show InChI InChI=1/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303523
PNG
(1-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3C(=O)CCC3=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H26N2O3/c1-21(2)20(22(21,3)4)19(27)15-13-23(16-8-6-5-7-14(15)16)11-12-24-17(25)9-10-18(24)26/h5-8,13,20H,9-12H2,1-4H3
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303521
PNG
(CHEMBL584534 | Cyclopentyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C20H26N2O2/c23-20(16-5-1-2-6-16)18-15-22(19-8-4-3-7-17(18)19)10-9-21-11-13-24-14-12-21/h3-4,7-8,15-16H,1-2,5-6,9-14H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303520
PNG
(CHEMBL571346 | Cyclobutyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C19H24N2O2/c22-19(15-4-3-5-15)17-14-21(18-7-2-1-6-16(17)18)9-8-20-10-12-23-13-11-20/h1-2,6-7,14-15H,3-5,8-13H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50303580
PNG
((trans-4-Isopropylcyclohexyl)(1-(2-morpholinoethyl...)
Show SMILES CC(C)[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C24H34N2O2/c1-18(2)19-7-9-20(10-8-19)24(27)22-17-26(23-6-4-3-5-21(22)23)12-11-25-13-15-28-16-14-25/h3-6,17-20H,7-16H2,1-2H3/t19-,20-
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>1.00E+4n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/a 0.770n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Binding affinity to CB2 receptor


Bioorg Med Chem 16: 1111-24 (2008)


Article DOI: 10.1016/j.bmc.2007.10.087
BindingDB Entry DOI: 10.7270/Q208665C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/a 0.770n/an/an/an/an/an/a



University of Innsbruck

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB2 receptor


J Med Chem 52: 369-78 (2009)


Article DOI: 10.1021/jm801044g
BindingDB Entry DOI: 10.7270/Q2VQ33M2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/a 330n/an/an/an/an/an/a



University of Innsbruck

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human recombinant CB1 receptor


J Med Chem 52: 369-78 (2009)


Article DOI: 10.1021/jm801044g
BindingDB Entry DOI: 10.7270/Q2VQ33M2
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303576
PNG
(CHEMBL583473 | [1-(2-Morpholin-4-ylethyl)-1H-indol...)
Show SMILES O=C(c1cn(CCN2CCOCC2)c2ccccc12)C12CC3CC1CC(C2)C3
Show InChI InChI=1/C24H30N2O2/c27-23(24-14-17-11-18(15-24)13-19(24)12-17)21-16-26(22-4-2-1-3-20(21)22)6-5-25-7-9-28-10-8-25/h1-4,16-19H,5-15H2
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n/an/an/an/a 68n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303577
PNG
((R)-(1-(2-Morpholinoethyl)-1H-indol-3-yl)(spiro[2....)
Show SMILES O=C(C1CC11CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H30N2O2/c26-22(20-16-23(20)8-4-1-5-9-23)19-17-25(21-7-3-2-6-18(19)21)11-10-24-12-14-27-15-13-24/h2-3,6-7,17,20H,1,4-5,8-16H2
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n/an/an/an/a 42n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303580
PNG
((trans-4-Isopropylcyclohexyl)(1-(2-morpholinoethyl...)
Show SMILES CC(C)[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C24H34N2O2/c1-18(2)19-7-9-20(10-8-19)24(27)22-17-26(23-6-4-3-5-21(22)23)12-11-25-13-15-28-16-14-25/h3-6,17-20H,7-16H2,1-2H3/t19-,20-
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n/an/an/an/a>1.00E+4n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303582
PNG
(CHEMBL570659 | Cycloheptyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C22H30N2O2/c25-22(18-7-3-1-2-4-8-18)20-17-24(21-10-6-5-9-19(20)21)12-11-23-13-15-26-16-14-23/h5-6,9-10,17-18H,1-4,7-8,11-16H2
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n/an/an/an/a 31n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303581
PNG
((trans-4-Ethylcyclohexyl)(1-(2-morpholinoethyl)-1H...)
Show SMILES CC[C@H]1CC[C@@H](CC1)C(=O)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1/C23H32N2O2/c1-2-18-7-9-19(10-8-18)23(26)21-17-25(22-6-4-3-5-20(21)22)12-11-24-13-15-27-16-14-24/h3-6,17-19H,2,7-16H2,1H3/t18-,19-
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n/an/an/an/a 85n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303583
PNG
(CHEMBL570874 | Cyclohexyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C21H28N2O2/c24-21(17-6-2-1-3-7-17)19-16-23(20-9-5-4-8-18(19)20)11-10-22-12-14-25-15-13-22/h4-5,8-9,16-17H,1-3,6-7,10-15H2
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n/an/an/an/a 86n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303521
PNG
(CHEMBL584534 | Cyclopentyl(1-(2-morpholinoethyl)-1...)
Show SMILES O=C(C1CCCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C20H26N2O2/c23-20(16-5-1-2-6-16)18-15-22(19-8-4-3-7-17(18)19)10-9-21-11-13-24-14-12-21/h3-4,7-8,15-16H,1-2,5-6,9-14H2
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n/an/an/an/a 819n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/an/an/a 16n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303520
PNG
(CHEMBL571346 | Cyclobutyl(1-(2-morpholinoethyl)-1H...)
Show SMILES O=C(C1CCC1)c1cn(CCN2CCOCC2)c2ccccc12
Show InChI InChI=1S/C19H24N2O2/c22-19(15-4-3-5-15)17-14-21(18-7-2-1-6-16(17)18)9-8-20-10-12-23-13-11-20/h1-2,6-7,14-15H,3-5,8-13H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/an/an/a 1.60n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at rat CB2 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/an/an/a 248n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at rat CB1 receptor assessed as inhibition of forskolin-induced cAMP production by cell based assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/an/an/a 0.520n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM21311
PNG
(4-(2-{3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3CCOCC3)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H30N2O2/c1-21(2)20(22(21,3)4)19(25)17-15-24(18-8-6-5-7-16(17)18)10-9-23-11-13-26-14-12-23/h5-8,15,20H,9-14H2,1-4H3
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n/an/a 330n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Binding affinity to CB1 receptor


Bioorg Med Chem 16: 1111-24 (2008)


Article DOI: 10.1016/j.bmc.2007.10.087
BindingDB Entry DOI: 10.7270/Q208665C
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50303523
PNG
(1-(2-(3-(2,2,3,3-Tetramethylcyclopropanecarbonyl)-...)
Show SMILES CC1(C)C(C(=O)c2cn(CCN3C(=O)CCC3=O)c3ccccc23)C1(C)C
Show InChI InChI=1S/C22H26N2O3/c1-21(2)20(22(21,3)4)19(27)15-13-23(16-8-6-5-7-14(15)16)11-12-24-17(25)9-10-18(24)26/h5-8,13,20H,9-12H2,1-4H3
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n/an/an/an/a 77n/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant CB2 receptor expressed in HEK293 cells coexpressing Galphaq/o5 assessed as calcium mobilization by FLIPR assay


J Med Chem 53: 295-315 (2010)


Article DOI: 10.1021/jm901214q
BindingDB Entry DOI: 10.7270/Q2KD1Z00
More data for this
Ligand-Target Pair
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