Compounds in cluster

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2 similar compounds to monomer 50383271

Wt: 229.0
BDBM21623

Wt: 270.7
BDBM67779

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 21623,67779
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hematopoietic prostaglandin D synthase (Homo sapiens (Human))	BDBM21623 (2,4-dichloro-6-(1H-pyrazol-5-yl)phenol \| Phenol, 1...) Show SMILES Oc1c(Cl)cc(Cl)cc1-c1cc[nH]n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	7.2	22
AstraZeneca					Assay Description The PGDS glutathione-S-transferase (GST) activity was measured by using MonoChloroBimane (MCB) as a chromogenic substrate. The assay was run at 384-w...				J Med Chem 51: 2178-86 (2008) Article DOI: 10.1021/jm701509k BindingDB Entry DOI: 10.7270/Q2Z036FR
AstraZeneca					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM67779 ((6Z)-4-chloranyl-6-(5-phenyl-1,2-dihydropyrazol-3-...) Show SMILES Oc1ccc(Cl)cc1-c1cc([nH]n1)-c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN
Emory University Curated by PubChem BioAssay					More data for this Ligand-Target Pair
X-box-binding protein 1 (Homo sapiens (Human))	BDBM67779 ((6Z)-4-chloranyl-6-(5-phenyl-1,2-dihydropyrazol-3-...) Show SMILES Oc1ccc(Cl)cc1-c1cc([nH]n1)-c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB
Emory University Curated by PubChem BioAssay					More data for this Ligand-Target Pair
DNA damage-inducible transcript 3 protein (Mus musculus)	BDBM67779 ((6Z)-4-chloranyl-6-(5-phenyl-1,2-dihydropyrazol-3-...) Show SMILES Oc1ccc(Cl)cc1-c1cc([nH]n1)-c1ccccc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ
Emory University Curated by PubChem BioAssay					More data for this Ligand-Target Pair