BindingDB logo
myBDB logout

17 similar compounds to monomer 50386292

Wt: 162.1
BDBM23990
Purchase
Wt: 246.1
BDBM50386294
Wt: 212.6
BDBM50386296
Wt: 192.2
BDBM50386297
Wt: 178.1
BDBM50386299
Purchase
Wt: 192.2
BDBM50386300
Wt: 192.2
BDBM50386301
Purchase
Wt: 192.2
BDBM50386302
Wt: 196.1
BDBM50386303
Wt: 192.2
BDBM50386306
Wt: 246.1
BDBM50386307
Wt: 212.6
BDBM50386308
Wt: 192.2
BDBM50386309
Purchase
Wt: 212.6
BDBM50386311
Wt: 192.2
BDBM50386312
Purchase
Displayed 1 to 15 (of 17 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 23990,50386294,50386296,50386297,50386299,50386300,50386301,50386302,50386303,50386306,50386307,50386308,50386309,50386311,50386312   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bacterial leucyl aminopeptidase


(Vibrio proteolyticus)
BDBM23990
PNG
(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Show SMILES NC1Cc2ccccc2NC1=O
Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
8.00E+4n/an/an/an/an/an/an/an/a



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)

More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM23990
PNG
(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Show SMILES NC1Cc2ccccc2NC1=O
Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)

More data for this
Ligand-Target Pair
Leukotriene A4 hydrolase


(Homo sapiens (human))
BDBM23990
PNG
(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Show SMILES NC1Cc2ccccc2NC1=O
Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)

More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386294
PNG
(CHEMBL2049095)
Show SMILES N[C@H]1Cc2cc(ccc2N(O)C1=O)C(F)(F)F
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-1-2-8-5(3-6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 29n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386296
PNG
(CHEMBL2049097)
Show SMILES N[C@H]1Cc2c(Cl)cccc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-3-8-5(6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 349n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386297
PNG
(CHEMBL2049098)
Show SMILES Cc1cccc2N(O)C(=O)[C@@H](N)Cc12
Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-9-7(6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 319n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386299
PNG
(CHEMBL2047852)
Show SMILES N[C@@H]1Cc2ccccc2N(O)C1=O
Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.17E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386300
PNG
(CHEMBL2047853)
Show SMILES CON1C(=O)[C@@H](N)Cc2ccccc12
Show InChI InChI=1S/C10H12N2O2/c1-14-12-9-5-3-2-4-7(9)6-8(11)10(12)13/h2-5,8H,6,11H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386301
PNG
(CHEMBL2047854)
Show SMILES CC1(N)Cc2ccccc2N(O)C1=O
Show InChI InChI=1S/C10H12N2O2/c1-10(11)6-7-4-2-3-5-8(7)12(14)9(10)13/h2-5,14H,6,11H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386302
PNG
(CHEMBL2047855)
Show SMILES C[C@@H]1[C@H](N)C(=O)N(O)c2ccccc12
Show InChI InChI=1S/C10H12N2O2/c1-6-7-4-2-3-5-8(7)12(14)10(13)9(6)11/h2-6,9,14H,11H2,1H3/t6-,9-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.33E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386303
PNG
(CHEMBL2047856)
Show SMILES N[C@H]1Cc2cccc(F)c2N(O)C1=O
Show InChI InChI=1S/C9H9FN2O2/c10-6-3-1-2-5-4-7(11)9(13)12(14)8(5)6/h1-3,7,14H,4,11H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 631n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386306
PNG
(CHEMBL2047859)
Show SMILES Cc1cccc2C[C@H](N)C(=O)N(O)c12
Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-7-5-8(11)10(13)12(14)9(6)7/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386307
PNG
(CHEMBL2047860)
Show SMILES N[C@H]1Cc2cccc(c2N(O)C1=O)C(F)(F)F
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-3-1-2-5-4-7(14)9(16)15(17)8(5)6/h1-3,7,17H,4,14H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>6.81E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386308
PNG
(CHEMBL2047861)
Show SMILES N[C@H]1Cc2ccc(Cl)cc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-5-3-7(11)9(13)12(14)8(5)4-6/h1-2,4,7,14H,3,11H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 118n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386312
PNG
(CHEMBL2049094)
Show SMILES Cc1ccc2N(O)C(=O)[C@@H](N)Cc2c1
Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-9-7(4-6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 30n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386311
PNG
(CHEMBL2049093)
Show SMILES N[C@H]1Cc2cc(Cl)ccc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-1-2-8-5(3-6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 258n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386312
PNG
(CHEMBL2049094)
Show SMILES Cc1ccc2N(O)C(=O)[C@@H](N)Cc2c1
Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-9-7(4-6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 402n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386294
PNG
(CHEMBL2049095)
Show SMILES N[C@H]1Cc2cc(ccc2N(O)C1=O)C(F)(F)F
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-1-2-8-5(3-6)4-7(14)9(16)15(8)17/h1-3,7,17H,4,14H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 488n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386296
PNG
(CHEMBL2049097)
Show SMILES N[C@H]1Cc2c(Cl)cccc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-3-8-5(6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>7.97E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386297
PNG
(CHEMBL2049098)
Show SMILES Cc1cccc2N(O)C(=O)[C@@H](N)Cc12
Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-9-7(6)5-8(11)10(13)12(9)14/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386299
PNG
(CHEMBL2047852)
Show SMILES N[C@@H]1Cc2ccccc2N(O)C1=O
Show InChI InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 219n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386300
PNG
(CHEMBL2047853)
Show SMILES CON1C(=O)[C@@H](N)Cc2ccccc12
Show InChI InChI=1S/C10H12N2O2/c1-14-12-9-5-3-2-4-7(9)6-8(11)10(12)13/h2-5,8H,6,11H2,1H3/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386301
PNG
(CHEMBL2047854)
Show SMILES CC1(N)Cc2ccccc2N(O)C1=O
Show InChI InChI=1S/C10H12N2O2/c1-10(11)6-7-4-2-3-5-8(7)12(14)9(10)13/h2-5,14H,6,11H2,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386302
PNG
(CHEMBL2047855)
Show SMILES C[C@@H]1[C@H](N)C(=O)N(O)c2ccccc12
Show InChI InChI=1S/C10H12N2O2/c1-6-7-4-2-3-5-8(7)12(14)10(13)9(6)11/h2-6,9,14H,11H2,1H3/t6-,9-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.28E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386303
PNG
(CHEMBL2047856)
Show SMILES N[C@H]1Cc2cccc(F)c2N(O)C1=O
Show InChI InChI=1S/C9H9FN2O2/c10-6-3-1-2-5-4-7(11)9(13)12(14)8(5)6/h1-3,7,14H,4,11H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 40n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386306
PNG
(CHEMBL2047859)
Show SMILES Cc1cccc2C[C@H](N)C(=O)N(O)c12
Show InChI InChI=1S/C10H12N2O2/c1-6-3-2-4-7-5-8(11)10(13)12(14)9(6)7/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.05E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386307
PNG
(CHEMBL2047860)
Show SMILES N[C@H]1Cc2cccc(c2N(O)C1=O)C(F)(F)F
Show InChI InChI=1S/C10H9F3N2O2/c11-10(12,13)6-3-1-2-5-4-7(14)9(16)15(17)8(5)6/h1-3,7,17H,4,14H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 174n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386308
PNG
(CHEMBL2047861)
Show SMILES N[C@H]1Cc2ccc(Cl)cc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-2-1-5-3-7(11)9(13)12(14)8(5)4-6/h1-2,4,7,14H,3,11H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 29n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386309
PNG
(CHEMBL2047862)
Show SMILES Cc1ccc2C[C@H](N)C(=O)N(O)c2c1
Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-7-5-8(11)10(13)12(14)9(7)4-6/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 37n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM50386311
PNG
(CHEMBL2049093)
Show SMILES N[C@H]1Cc2cc(Cl)ccc2N(O)C1=O
Show InChI InChI=1S/C9H9ClN2O2/c10-6-1-2-8-5(3-6)4-7(11)9(13)12(8)14/h1-3,7,14H,4,11H2/t7-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 36n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair
Cytosol aminopeptidase


(Bos taurus (bovine))
BDBM23990
PNG
(3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...)
Show SMILES NC1Cc2ccccc2NC1=O
Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+6n/an/an/an/a8.030



ENSCMu



Assay Description
Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...


Bioorg Med Chem 14: 7241-57 (2006)

More data for this
Ligand-Target Pair
Kynurenine/alpha-aminoadipate aminotransferase


(Rattus norvegicus)
BDBM50386309
PNG
(CHEMBL2047862)
Show SMILES Cc1ccc2C[C@H](N)C(=O)N(O)c2c1
Show InChI InChI=1S/C10H12N2O2/c1-6-2-3-7-5-8(11)10(13)12(14)9(7)4-6/h2-4,8,14H,5,11H2,1H3/t8-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 368n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrs


Citation and Details
More data for this
Ligand-Target Pair