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2 similar compounds to monomer 23515

Compile data set for download or QSAR
Wt: 167.1
BDBM26118
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Wt: 137.1
BDBM50216534
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26118,50216534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone Lysine Demethylase


(Homo sapiens (Human))
BDBM26118
PNG
(pyridine carboxylate, 6f | pyridine-3,5-dicarboxyl...)
Show SMILES OC(=O)c1cncc(c1)C(O)=O
Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-5(7(11)12)3-8-2-4/h1-3H,(H,9,10)(H,11,12)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+7n/an/an/an/a7.537



University of Oxford



Assay Description
A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...


J Med Chem 51: 7053-6 (2008)


Article DOI: 10.1021/jm800936s
BindingDB Entry DOI: 10.7270/Q2959FV4
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50216534
PNG
(5-methylnicotinic acid | CHEMBL247132)
Show SMILES Cc1cncc(c1)C(O)=O
Show InChI InChI=1S/C7H7NO2/c1-5-2-6(7(9)10)4-8-3-5/h2-4H,1H3,(H,9,10)
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a 1.60E+4n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test


Bioorg Med Chem Lett 17: 4914-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.028
BindingDB Entry DOI: 10.7270/Q2NP244M
More data for this
Ligand-Target Pair
D-Aspartate Oxidase (DDO)


(Homo sapiens (Human))
BDBM50216534
PNG
(5-methylnicotinic acid | CHEMBL247132)
Show SMILES Cc1cncc(c1)C(O)=O
Show InChI InChI=1S/C7H7NO2/c1-5-2-6(7(9)10)4-8-3-5/h2-4H,1H3,(H,9,10)
KEGG

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 5.47E+6n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...


J Med Chem 58: 7328-40 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00871
BindingDB Entry DOI: 10.7270/Q2WM1G6R
More data for this
Ligand-Target Pair
D-Aspartate Oxidase (DDO)


(Homo sapiens (Human))
BDBM26118
PNG
(pyridine carboxylate, 6f | pyridine-3,5-dicarboxyl...)
Show SMILES OC(=O)c1cncc(c1)C(O)=O
Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-5(7(11)12)3-8-2-4/h1-3H,(H,9,10)(H,11,12)
KEGG

GoogleScholar
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+7n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...


J Med Chem 58: 7328-40 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00871
BindingDB Entry DOI: 10.7270/Q2WM1G6R
More data for this
Ligand-Target Pair
D-amino-acid oxidase


(Homo sapiens (Human))
BDBM50216534
PNG
(5-methylnicotinic acid | CHEMBL247132)
Show SMILES Cc1cncc(c1)C(O)=O
Show InChI InChI=1S/C7H7NO2/c1-5-2-6(7(9)10)4-8-3-5/h2-4H,1H3,(H,9,10)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

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DrugBank
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Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.50E+6n/an/an/an/an/an/a



Kitasato University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DAO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...


J Med Chem 58: 7328-40 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00871
BindingDB Entry DOI: 10.7270/Q2WM1G6R
More data for this
Ligand-Target Pair